Salmonella enterica subsp. enterica serovar Choleraesuis: SCH_0374
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Entry
SCH_0374 CDS
T00240
Symbol
ledL
Name
(GenBank) putative 3-isopropylmalate isomerase (dehydratase), subunit with LeuD
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sec
Salmonella enterica subsp. enterica serovar Choleraesuis
Pathway
sec00290
Valine, leucine and isoleucine biosynthesis
sec00660
C5-Branched dibasic acid metabolism
sec01100
Metabolic pathways
sec01110
Biosynthesis of secondary metabolites
sec01210
2-Oxocarboxylic acid metabolism
sec01230
Biosynthesis of amino acids
Module
sec_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sec00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
SCH_0374 (ledL)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SCH_0374 (ledL)
Enzymes [BR:
sec01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
SCH_0374 (ledL)
4.2.1.35 (R)-2-methylmalate dehydratase
SCH_0374 (ledL)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
AAX64280
UniProt:
Q57SN1
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All DBs
Position
417311..418732
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AA seq
473 aa
AA seq
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MSAKTLYEKLVESHTIRELDNEGHVLLYIDRSILNEYTSPQAFSGLRERGRAVRHPDTFL
LNIDHVNPTRSQRDVLMTDPGGQLQVDYFRENAADFGITLFDVLDPRQGIEHVVAHEQGL
VMPGMVIAAGDSHTTTYGAFGALGFGIGTSEIEHLLATQTLVYRKLKTMRVSVQGELPFA
CSAKDIVLELLERIGADGATGYAIEFVGEAISALSVEGRMTLCNMAVEAGARGAIIAPDK
KVFDYIYGKPQMPVGELWQQALLEWSQLSSDADAVFDKTVAINCHDLEPKVTWGISPDQT
GSITGRVPFPEQETNPLKRLALEKALHYMGLTAGMLLKDIRISHAFIGSCTNGRIEDLRA
VAKVLEGRKIASHVRGIIVPGSTMVRRQAEEEGLAKIFIAAGFEWRQSGCSMCLAMNEDV
LSPGDRCASGTNRNFLGRQGAGARTHLMSPAMVAAAAVAGHLVDVRSLLQAGE
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
atgtctgctaaaacgctgtatgaaaaattagttgagtcacataccattcgtgaacttgat
aacgaaggacatgttttactttatattgatcgttcaatactgaatgaatataccagcccg
caggcatttagcgggttaagagaacgcggtcgcgccgttcggcaccccgacacgttttta
ttgaatattgaccatgttaatcccacgcggtcgcaacgggatgtcttaatgaccgatccg
ggaggacagctacaggttgattactttcgggaaaatgccgctgactttggcatcacatta
tttgatgtgctggatccgcgtcaggggattgaacacgtggttgctcatgaacaagggcta
gtgatgcctggcatggtgatcgccgccggggatagtcacacgacaacctacggtgcattt
ggcgcgctgggctttggtatcgggacgtcggaaattgaacatctgctggccacgcagacg
ctggtttaccgcaagctcaaaaccatgcgcgtaagtgttcagggagagctacctttcgcc
tgttccgcaaaagatattgttcttgaattgcttgaacgtattggcgctgatggcgcgacg
ggatatgccattgaatttgtgggtgaggccatcagcgcgttgagcgttgaaggacgaatg
acgctctgcaacatggcggtagaagcgggggcgcgtggtgctattattgcgccggataaa
aaggtttttgactatatctacggtaaaccgcaaatgcctgtaggtgaactctggcagcag
gcattgctggaatggtcacagttgagcagcgatgctgatgcggtatttgataagacggtg
gcgatcaactgccatgatcttgagcctaaagtcacctggggaatcagtccggatcaaaca
ggttccatcaccggacgtgttcctttcccggaacaggaaaccaatccgcttaagcgcctg
gcgcttgagaaggcccttcattacatgggattaacggctggcatgttgctgaaagatatt
cgtatctctcacgcttttattggttcatgcacaaatggtcgcattgaggatttgcgtgcc
gttgcgaaggtgcttgaagggcgcaaaatcgccagccatgttcgcgggatcattgtgcct
ggttcaacaatggtaagacgccaggcggaagaagaaggactggcgaaaatctttattgct
gccggttttgaatggcggcagtcgggttgctcaatgtgccttgcgatgaatgaagatgta
ttgtcgcccggcgatcgctgtgcatcaggtacgaatcgtaacttccttggacgacagggc
gctggagcaagaacgcatttgatgagcccggcgatggttgcggcggcggcggtagcgggg
catctggtcgatgttcggtcattacttcaggcaggggaataa
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