Streptomyces endophytica: OJ254_01535
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Entry
OJ254_01535 CDS
T09208
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
seng
Streptomyces endophytica
Pathway
seng00290
Valine, leucine and isoleucine biosynthesis
seng00660
C5-Branched dibasic acid metabolism
seng01100
Metabolic pathways
seng01110
Biosynthesis of secondary metabolites
seng01210
2-Oxocarboxylic acid metabolism
seng01230
Biosynthesis of amino acids
Module
seng_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
seng00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
OJ254_01535 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
OJ254_01535 (leuC)
Enzymes [BR:
seng01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
OJ254_01535 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
OJ254_01535 (leuC)
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Motif
Pfam:
Aconitase
YopE_N
Motif
Other DBs
NCBI-ProteinID:
UZJ29410
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Position
complement(349414..350838)
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKAGRQVRRTDLTIAT
EDHNTPTLDIDKPIADPVSRTQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLAPFKTMAITVDGELPEGVTA
KDLILAIIARIGTGGGQGYVIEYRGPAIEKLSMEARMTICNMSIEAGARAGMIAPDQTTF
DYLQGRDHAPQGADWDAAVEYWKTLRTDDDAVFDAEVRIDAAALAPFVTWGTNPGQGAPL
SAQVPDPASYEDASERLAAEKALEYMGLTAGQPLREITVDTVFVGSCTNGRIEDLRSAAS
ILEGRKVADGVRMLIVPGSVRVSLEAVAEGLDKVFTAAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDVATPAGV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggacggacactcgcggagaaggtctgggacgaccacgtcgtccggcgcgcggaaggc
gagcccgacctcctcttcattgatctgcacctgctgcacgaggtcaccagcccgcaggcg
ttcgacggcctccgcaaggccggccgccaggtgcgccggacggacctgaccatcgccacc
gaggatcacaacaccccgaccctcgacatcgacaagccgatcgccgacccggtctcgcgc
acccagctggagacgctgcgcaagaactgcgccgagttcggcgtccggctgcacccgctc
ggcgacgtcgagcagggtgtcgtccacgtcgtgggcccccagctgggactgacccagccg
ggtaccaccgtggtctgcggtgacagccacacgtccacccacggcgccttcggcgcgctg
gcgttcggtatcggcaccagtcaggtcgagcacgtgctggccacccagacgctgccgctg
gccccgttcaagacgatggcgatcaccgtcgacggcgagctgccggagggcgtgaccgcc
aaggacctgatcctggcgatcatcgcccggatcggcaccggcggcggccagggatacgtc
atcgaataccgcggtccggccatcgagaagctctcgatggaggcccggatgaccatctgc
aacatgtcgatcgaggcgggcgcccgggccggcatgatcgccccggaccagaccaccttc
gactacctccagggccgcgaccacgccccccagggcgcggactgggacgccgcggtcgag
tactggaagacgctgcgcaccgacgatgacgcggtcttcgacgccgaggtgcgcatcgac
gccgccgcgctggcgccgttcgtcacctggggcaccaacccgggccagggcgccccgctt
tcggcgcaggtccccgacccggcttcgtacgaggacgcctcggagcgactggccgccgaa
aaggccctggagtacatggggttgacggcgggtcagccgctgcgcgagatcaccgtggac
accgtcttcgtaggttcctgcaccaacggccgcatcgaggacctgcgctccgcggcgtcg
atcctggagggccgtaaggtcgcagacggcgtacggatgctgatcgttcccggctcggtc
cgggtctccctggaagcggtcgccgaggggctggacaaggtcttcaccgcggcgggcgcc
gaatggcggcacgcgggctgctcgatgtgcctgggcatgaaccccgaccagctggcgccc
ggtgagcgctcggcgtccacctccaaccgcaacttcgagggccgccagggcaagggcggt
cgtacgcacctggtctcgccgcaggtggccgccgcaacggcggttctcggccatctggcc
tcaccggccgacctgtccgacgtcgccacgcccgcgggagtctga
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