Streptomyces ferrugineus: IM697_41760
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Entry
IM697_41760 CDS
T07428
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sfeu
Streptomyces ferrugineus
Pathway
sfeu00860
Porphyrin metabolism
sfeu01100
Metabolic pathways
sfeu01110
Biosynthesis of secondary metabolites
sfeu01120
Microbial metabolism in diverse environments
sfeu01240
Biosynthesis of cofactors
Module
sfeu_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
sfeu_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sfeu_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sfeu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
IM697_41760
Enzymes [BR:
sfeu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
IM697_41760
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
IM697_41760
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
RodZ_C
Motif
Other DBs
NCBI-ProteinID:
QOV36448
UniProt:
A0A7M2SLU5
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Position
complement(9397519..9399225)
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AA seq
568 aa
AA seq
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MSPTTLPAGLEHGHVTFLGAGPGDPGLLTLRAVEALANADVLVAEHEVLDVVRKHTRTGV
AEVHTDTGPDGDAAPGTGTPQLAVVDGASTTAGSPAVRDAAHLVMEAARSGRRVVRAVSG
DPGLDAYATEEMLACAAAGVPFEVVPGVAAAVGVPAYAGVPLRDAQGTDVRFVDARTASD
RCWTEVGASDGTVVVSTTLDAVGAAAGELVSAGRKPDTPLTVTVAGTTTRQRTWSATLGT
IAQTLKQAKVLPSPEGGRPVIAVVGERSATAQRDQLSWFESKPLFGWRVLVPRTKEQAAS
LSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFE
EYGLDARAFAGIKVAAVGEQTAKALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPID
RVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSS
STVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALADFGMRR
RAAALEAGDAVTRPSERRPGARRRRSTT
NT seq
1707 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccacccttcccgccggccttgaacacgggcacgtcaccttcctcggtgcc
ggacccggggatccggggctgctgactctgcgtgccgtcgaggcgctggcgaacgccgat
gtactcgtcgccgagcacgaagtgctcgacgtggtacgcaagcacaccagaaccggtgtc
gccgaagtgcacacggacacgggtcccgatggggacgccgcgccgggcacaggcacgcct
caactagcggttgttgacggcgcgtcgacaaccgctgggtcacccgcggtgcgggatgcc
gcacatcttgtcatggaggccgcgcgcagcggcaggcgggtcgtgcgtgcggtgtccggg
gatcccgggctcgacgcgtacgccaccgaggagatgctggcgtgcgccgcggcgggcgtg
ccgttcgaggtcgtgccgggcgtggcggcggccgtgggcgtgcccgcgtatgccggggtg
ccgctgcgggacgcgcagggcacggacgtgcgattcgtggacgcgcggacggcctcggac
cggtgctggaccgaggtgggcgcgtccgacgggaccgtcgtcgtctcgacgacgctcgac
gccgtgggtgcggccgccggtgagctggtgtcggcggggcgcaagcccgatacgccgttg
acggtcaccgtcgccggtacgaccacgcgtcagcggacctggagcgcgacgctcgggacc
atcgcgcagacgctgaagcaggccaaggtgctgccgtcgcccgagggcgggcgaccggtg
atagccgtggtcggtgagcgttccgccactgctcagcgtgatcagctgtcgtggttcgag
tccaagccgctcttcgggtggcgggtgctggtgccgcggacgaaggagcaggcggcgtct
ctctccgaccagttgcggtcgtacggggccgtgccgcacgaggtgccgacgatcgccgtc
gagccgccgcggacgccccagcagatggagcgggcggtcaaggggctggtgaccgggcgg
tacgagtggatcgccttcacctcggtgaacgcggtcaaggccgtgcgggagaagttcgag
gagtacgggctcgatgcccgggcgttcgccgggatcaaggtcgcggcggtgggggagcag
acggccaaggcgctgatcgccttcggtgtgaagccggatctcgtgccgagtggggagcag
tcggccgcggggctgctggaggactggccgccgtacgatccggtctttgatccgatcgac
cgggtgttcctgcctcgggccgacatcgccacggagacgctggtcgccgggctgatcgag
ctcggctgggaggtcgacgacgtcacggcgtatcggaccgtgcgggcctcgccgccgccg
gcggagactcgggaggcgatcaaggggggtggcttcgatgccgttctcttcacgtcgtcg
tcgaccgtgcggaatctggtggggatcgccgggaagccgcacaacgtgacggtgatcgcg
tgtatcgggcccgccaccgcgaagactgccgaggagcacgggctccgggtggatgtgatg
gctccggagccgtcggtgcacaagttggccgaggcgttggccgacttcgggatgcggcgg
agggccgccgcgctggaggccggggacgcggttactcggccgagtgagcgtcggccgggg
gctcggcggcggcggtccaccacgtag
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