Streptomyces microflavus: SFUL_5447
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Entry
SFUL_5447 CDS
T02650
Name
(GenBank) LEUC 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sfi
Streptomyces microflavus
Pathway
sfi00290
Valine, leucine and isoleucine biosynthesis
sfi00660
C5-Branched dibasic acid metabolism
sfi01100
Metabolic pathways
sfi01110
Biosynthesis of secondary metabolites
sfi01210
2-Oxocarboxylic acid metabolism
sfi01230
Biosynthesis of amino acids
Module
sfi_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sfi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
SFUL_5447
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SFUL_5447
Enzymes [BR:
sfi01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
SFUL_5447
4.2.1.35 (R)-2-methylmalate dehydratase
SFUL_5447
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
AGK80335
UniProt:
N0CX99
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All DBs
Position
6041567..6042994
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AA seq
475 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRQAGRPVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCADFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVDGELPEDVTA
KDLILAIITRIGTGGGQGYILEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLEGRDRAPRGEEWDAAVAYWKTLRSDDDAVFDAEVVIDATELAPFVTWGTNPGQGAPL
SAHVPDPASYEDASERNAAEKALEYMGLTAGQPLREINVDTVFVGSCTNGRIEDLRNAAA
ILDGRKVANGVRMLVVPGSVRVALQAVSEGLDKVFTEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDTRTPAGVR
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggaaaaggtctgggacgaccatgtcgtccggcgcgcggagggc
gagcccgaccttctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggtctgcgccaggccggacgtccggtgcgacgcctcgacctcaccatcgccacc
gaggaccacaacaccccgacgctcgacatcgacaagccgatcgccgacccggtctcccgc
gcccagctggagaccctgcgcaagaactgcgcggacttcggcgtccggctgcaccccctc
ggcgacgtcgagcagggcgtcgtgcacgtggtcggcccgcagctgggcctgacccagccc
ggcaccaccgtggtctgcggcgactcccacacctccacgcacggggccttcggcgcactg
gcgttcggcatcggcaccagccaggtggagcacgtcctggccacccagacgctgccgctg
gcccgcccgaagaccatggccatcacggtcgacggcgaactgcccgaggacgtcaccgcc
aaggacctgatcctcgccatcatcacccggatcggcaccggcggcggccagggctacatc
ctcgaataccgcggctccgccatcgagaagctctcgatggaggcccggatgaccatctgc
aacatgtcgatcgaggccggtgcccgcgcgggcatgatcgccccggacgagaccaccttc
gcctacctggagggccgcgaccgcgcccccaggggcgaggagtgggacgccgccgtcgcg
tactggaagaccctgcgctcggacgacgacgcggtgttcgacgccgaggtcgtcatcgac
gccaccgaactggcgccgttcgtcacctggggcaccaacccgggccagggcgcgccgctc
tccgcgcacgtccccgaccccgcttcgtacgaggacgcctcggagcgcaacgccgcggaa
aaggccctggagtacatggggttgaccgcgggccagccgctgcgcgagatcaacgtggac
accgtcttcgtaggttcgtgcaccaatggccgcatcgaggacctgcgcaacgccgccgcc
atcctggacggccgcaaagtcgcgaacggcgtacggatgctggtcgtccccggctcggtc
cgggtcgcgctccaggccgtctccgagggcctggacaaggtcttcaccgaggccggcgcc
gaatggcggcacgcgggttgctcgatgtgcctcggcatgaaccccgaccagctggccccc
ggcgagcgctccgcctccacctcgaaccgcaacttcgagggccggcagggcaagggcggc
cgcacccacctggtctcgccccaggtcgccgccgccaccgccgtgctgggccatctggcc
tcgcccgccgacctgtccgacacccgtacccccgccggagtccgatag
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