Streptomyces ficellus: EIZ62_20605
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Entry
EIZ62_20605 CDS
T06929
Name
(GenBank) uroporphyrinogen-III synthase
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
sfic
Streptomyces ficellus
Pathway
sfic00860
Porphyrin metabolism
sfic01100
Metabolic pathways
sfic01110
Biosynthesis of secondary metabolites
sfic01120
Microbial metabolism in diverse environments
sfic01240
Biosynthesis of cofactors
Module
sfic_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sfic_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sfic00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
EIZ62_20605
Enzymes [BR:
sfic01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
EIZ62_20605
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Gene cluster
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Motif
Pfam:
HEM4
Trans_reg_C
Motif
Other DBs
NCBI-ProteinID:
QGV80363
UniProt:
A0A6I6F8T0
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All DBs
Position
4569055..4570203
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AA seq
382 aa
AA seq
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MHEQQDGSHGPLAGFTVGVTAARRADELGALLERRGGAVQHAPALRIVPLADDTELLHAT
KALVGHAPDIVVATTAIGFRGWLEAADGWGYGEELRSRLRGAQVLARGPKVKGAVRAAGL
TEEWSPASDSMAEVLDRLLGQDVTGRRIALQLHGEPLPGFVEALRAAGAEVVVVPVYRWM
PPEDLAPLDRLIDATVARSLDAVTFTSAPAGASLLSRAQDRGLLPGLLDALRGDVLAACV
GPVTALPLQAHGIETVQPARFRLGPLVQLLCQELPARARTLPVAGRRIEIRGHAVLVDGD
LRPVPPAGMSLLHSLARRPGWVVSRADLLRALPGAGRDEHAVETAMARLRSALGAPKLIQ
TVVKRGYRLALDPGADAKYADG
NT seq
1149 nt
NT seq
+upstream
nt +downstream
nt
atgcacgagcaacaggatggttcccacggcccgctggccggcttcaccgtcggcgtcacc
gccgcccgccgcgccgacgagctgggcgcgctgctggaacgccgcgggggagcggtccag
cacgccccggcactgcgcatcgtgccgctcgccgacgacaccgagctcctccacgccacc
aaggccctcgtgggccacgccccggacatcgtggtcgccaccaccgcgatcggcttccgc
ggctggctggaggcggccgacggctgggggtacggggaggagctccggagccggctgcgc
ggcgcccaggtcctcgcccggggccccaaggtcaagggcgcggtacgggccgccgggctc
accgaggagtggtcgcccgcctccgactccatggccgaagtcctcgaccggctcctcggg
caggacgtgacggggcgccgcatcgcgctccagctgcacggcgagccgctgccggggttc
gtggaggccctgcgggcggcgggcgccgaggtggtggtcgttcccgtctaccggtggatg
ccgcccgaggacctcgcgcccctggaccggctcatcgacgcgacggtcgcccggtcgctg
gacgcggtgaccttcaccagcgccccggccggcgcctcgctgctgtcccgcgcccaggac
cggggcctgctgcccggactgctcgacgcgctgcgcggcgacgtgctggccgcctgcgtc
gggccggtcaccgccctgccgctccaggcgcacggcatcgagaccgtccagccggcccgg
ttccggctcggcccgctggtccagctgttgtgccaggagctgcccgcgcgggcccgtacg
ctcccggtcgcggggcgccgcatcgagatccggggccacgccgtcctggtcgacggcgac
ctgcggcccgtgccgcccgcgggcatgtccctgctccactctctggcccgccgccccggc
tgggtcgtctcccgcgccgacctgctgcgcgccctgcccggcgcgggccgcgacgagcac
gccgtggagaccgcgatggcccgcctccgctcggccctgggcgcgcccaagctcatccag
accgtcgtcaagcgcggctaccgtctcgccctggacccgggcgccgacgccaagtacgcg
gacgggtga
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