Streptomyces formicae: KY5_4542
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Entry
KY5_4542 CDS
T05416
Name
(GenBank) Uroporphyrinogen-III methyltransferase / Uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sfk
Streptomyces formicae
Pathway
sfk00860
Porphyrin metabolism
sfk01100
Metabolic pathways
sfk01110
Biosynthesis of secondary metabolites
sfk01120
Microbial metabolism in diverse environments
sfk01240
Biosynthesis of cofactors
Module
sfk_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sfk_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sfk00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
KY5_4542
Enzymes [BR:
sfk01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
KY5_4542
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
KY5_4542
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
ATL29560
UniProt:
A0A291QCP5
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Position
5333363..5335021
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AA seq
552 aa
AA seq
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MSPTSNLPGTPAHGHVTFLGAGPGDPGLLTLRAVEALARADVLIAEPDVLDVVRPHARGG
VDTPRPTVADEASAAVDTPSARAAANLVMEAARGGRRVVRAVSGDPGLDTYAAGEMLACA
AEGISFEVVPGIAAAVGVPAYAGVPLRDAEGTDVRFVDARTASDRCWNEVGVSDGTVVVS
TSLDSVASAAGELVSAGRKPDTPMTVTVAGTTTRQRTWTATLGTIAQVLKQAKVLPSPDG
GQPVIVVVGERSAAAQRDQLSWFESKPLFGWRVLVPRTKEQAASLSDQLRSYGAVPHEVP
TIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKVAA
VGEQTAAALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATETLVA
GLIDLGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHNV
TVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALAEFGSRRRAASLEAGDPVTRPSE
RRPGSRRRRTAP
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccacctcgaaccttcccggcactcccgcacacgggcacgtcaccttcctgggt
gccggacccggagatccgggactgctgaccctgcgcgccgtcgaggcgctggcccgagcg
gatgtgctgatcgccgagcccgatgtgctcgacgtcgtccgcccgcacgccaggggaggt
gtggacacaccccggccgacggttgctgacgaggcgtcagcggccgttgacacgccctct
gcccgagccgccgccaatcttgtcatggaggcagcgaggggcggcaggcgggtcgtgcgc
gcggtcagcggcgatccgggcctcgacacctacgcggcgggcgagatgctcgcctgcgcc
gccgagggcatctccttcgaggtggtgcccggcatcgcggccgccgtcggcgtgcccgcc
tacgcgggtgtgccgctgcgcgacgcggagggcacggacgtgcgcttcgtcgacgcccgt
acggcgtcggaccgttgctggaacgaggtgggtgtctcggacggcactgtcgtcgtctcc
acgtcgctcgactcggtggcgtcggccgccggtgagctggtgtccgcgggccgcaagccc
gacaccccgatgaccgtgacggtggccggtacgacgacgcgccagcgcacctggaccgcg
acgctcggcaccatcgcgcaggtcctcaagcaggccaaggtgctgccgtcgccggacggc
gggcagcccgtcatagtcgtggtcggcgaacgctcggccgccgcccagcgcgaccagctg
tcgtggttcgagtcgaagccgctcttcgggtggcgggtgctggtgccgcgcacgaaggag
caggcggcctcgctctccgaccagctgcgttcgtacggcgcggtgccgcacgaggtgccg
accatcgcggtcgaaccgccgcgcacgccccagcagatggagcgcgcggtcaagggcctc
gtcacgggtcgctacgagtggatcgccttcaccagcgtcaacgcggtcaaggcggtgcgc
gagaagttcgaggagtacgggctcgacgcgcgggccttcgccgggatcaaggtcgcggcc
gtcggcgagcagaccgccgccgcgctgatcgccttcggcgtcaagccggacctggtgccc
agcggtgagcagtccgccgccggtctccttgaggactggccgccgtacgacccggtcttc
gacccgatcgaccgcgtcttcctgccgcgggccgacatcgccacggagactctggtcgcg
ggcctgatcgacctcggctgggaggtcgacgacgtcaccgcctaccggaccgtgcgcgct
tcgccgccgccggccgagacgcgcgaggcgatcaagggcggtggcttcgacgccgtgctc
ttcacctcctcgtcgaccgtgcggaacctcgtcggcatcgcgggcaagccgcacaacgtg
accgtgatcgcgtgtatcggcccggcgacggccaagaccgcggaggagcacgggctccgg
gtggacgtgatggctcccgagccgtcggtccacaagctggccgaggcgttggccgagttc
ggatctcggcggagagccgcgtcgctggaggcgggggaccctgtcacccggcccagtgag
cgtcggcccggttcgcgtcggcgacgcaccgcgccgtag
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