Streptomyces flavofungini: QUY26_10590
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Entry
QUY26_10590 CDS
T09698
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sfp
Streptomyces flavofungini
Pathway
sfp00290
Valine, leucine and isoleucine biosynthesis
sfp00660
C5-Branched dibasic acid metabolism
sfp01100
Metabolic pathways
sfp01110
Biosynthesis of secondary metabolites
sfp01210
2-Oxocarboxylic acid metabolism
sfp01230
Biosynthesis of amino acids
Module
sfp_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sfp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
QUY26_10590 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
QUY26_10590 (leuC)
Enzymes [BR:
sfp01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
QUY26_10590 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
QUY26_10590 (leuC)
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Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
WJV45944
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Position
complement(2716114..2717538)
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRQAGRQVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVDGELPDGVTA
KDLILAIIARIGTGGGQGYILEYRGPAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYIKDRAHAPQGADWDEAVAYWKTLRTDDDAVFDAEVYIDAAELSPFVTWGTNPGQGLPL
SGHVPDPASYEDASERLAAEKALEYMGLSAGQRLRDIKVDTVFVGSCTNGRIEDLRSAAA
VLDGRKVADGVRMLVVPGSVRVALQAVEEGLDKVFTAAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVTGHLASPADLADAPTTAGV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggactctcgcggagaaggtctgggacgaccacgtcgtccggcgcgccgaaggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgacgagcccgcaggcg
ttcgacggcctccggcaggcaggacgccaggtgcggcgcctcgatctgaccatcgccacc
gaggaccacaacaccccgaccctcgacatcgacaagcccatcgccgaccccgtctcccgc
gcccagctggagacgctgcgcaagaactgcgccgagttcggcgtccggctgcacccgctc
ggcgacgtcgagcagggcgtcgtccacgtggtgggaccgcagctgggactgacccagccc
ggcaccacggtggtctgcggcgactcccacacctccacgcacggcgccttcggcgcgctg
gccttcggcatcggcacctcccaggtggagcacgtcctcgcgacccagacgctgccgctg
gcccgccccaagaccatggccatcaccgtcgacggcgaactgcccgacggcgtcaccgcc
aaggacctgatcctcgccatcatcgcccggatcggcaccggcggcggccagggctacatc
ctggagtaccgcggcccggccatcgagaagctctcgatggaggcccgcatgaccatctgc
aacatgtccatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagacgaccttc
gcgtacatcaaggaccgcgcccacgccccgcagggcgccgactgggacgaggccgtcgcg
tactggaagacgctgcgcaccgacgacgacgccgtcttcgacgccgaggtctacatcgac
gccgccgagctctccccgttcgtcacctggggcaccaacccgggccagggcctgcccctg
tcgggacacgtccccgacccggcttcgtacgaagacgcttcggagcggctcgccgccgaa
aaggccctggagtacatggggttgagcgccggacagcggctgcgggacatcaaggtggac
accgtcttcgtaggctcctgcaccaacggccgtatcgaagacctccgatcagccgccgcc
gtcctcgacgggcgcaaagtcgccgacggcgtacggatgctggtggtgcccggctcggtg
cgggtcgccctgcaggccgtcgaggagggcctggacaaggtgttcaccgcggcgggcgcc
gaatggcggcacgcgggctgctcgatgtgcctgggcatgaaccccgaccaactcgccccc
ggcgagcgctccgcgtccacgtccaaccgcaacttcgagggccgtcagggcaagggcgga
cgcacccatctggtgtcgccgcaggtcgccgccgccaccgcggtcaccggccacctggca
tcgcccgccgacctcgccgacgcccccacgaccgccggagtctga
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