| Entry |
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| Symbol |
metL
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| Name |
(GenBank) bifunctional aspartate kinase II/homoserine dehydrogenase II,Aspartokinase II/homoserine dehydrogenase II,bifunctional aspartate kinase II/homoserine dehydrogenase II,Homoserine dehydrogenase,aspartate kinase,Homoserine dehydrogenase
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| KO |
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| Organism |
sft Shigella flexneri NCTC1 (serotype 2a)
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| Pathway |
| sft00260 | Glycine, serine and threonine metabolism |
| sft00270 | Cysteine and methionine metabolism |
| sft01110 | Biosynthesis of secondary metabolites |
| sft01120 | Microbial metabolism in diverse environments |
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| Module |
| sft_M00016 | Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine |
| sft_M00017 | Methionine biosynthesis, aspartate => homoserine => methionine |
| sft_M00018 | Threonine biosynthesis, aspartate => homoserine => threonine |
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| Brite |
KEGG Orthology (KO) [BR:sft00001]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
NCTC1_04348 (metL)
00270 Cysteine and methionine metabolism
NCTC1_04348 (metL)
00300 Lysine biosynthesis
NCTC1_04348 (metL)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
NCTC1_04348 (metL)
Enzymes [BR:sft01000]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
NCTC1_04348 (metL)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
NCTC1_04348 (metL)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
1:4061471..4063903
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| AA seq |
810 aa
MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEFSQPDDMMVVSAAGSTTNQLINW
LKLSQTDRLSAHQVQQTLRRYQCDLISGLLPAEEADSLISAFVSDLERLAALLDSGINDA
VYAEVVGHGEVWSARLMSAVLNQQGLPAAWLDAREFLRAERAAQPQVDEGLSYPLLQQLL
VQHPSKRLVVTGFISRNNAGETVLLGRNGSDYSATQIGALAGVSRVTIWSDVAGVYSADP
RKVKDACLLPLLRLDEASELARLAAPVLHARTLQPVSGSEIDLQLRCSYTPDQGSTRIER
VLASGTGARIVTSHDDVCLIEFQVPASQDFKLAHKEIDQILKRAQVRPLAVGVHNDRQLL
QFCYTSEVADSALKILDEAGLPGELRLRQGLALVAMVGAGVTRNPLHCHRFWQQLKGQPV
EFTWQSDDGISLVAVLRTGPTESLIQGLHQSVFRAEKRIGLVLFGKGNIGSRWLELFARE
QSTLSARTGFEFVLAGVVDSRRSLLSYDGLDASRALAFFNDEAVEQDEESLFLWMRAHPY
DDLVVLDVTASQQLADQYLDFASHGFHVISANKLAGASDSNKYRQIHDAFEKTGRHWLYN
ATVGAGLPINHTVRDLIDSGDTILSISGIFSGTLSWLFLQFDGSVPFTELVDQAWQQGLT
EPDPRDDLSGKDVMRKLVILAREAGYNIEPDQVRVESLVPAHCEGGSIDHFFENGDELNE
QMVQRLEAAREMGLVLRYVARFDANGKARVGVEAVREDYPLASLLPCDNVFAIESRWYRD
NPLVIRGPGAGRDVTAGAIQSDINRLAQLL |
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| NT seq |
2433 nt +upstreamnt +downstreamnt
atgagtgtgattgcgcaggcaggggcgaaaggtcgtcagctgcataaatttggtggcagt
agtctggctgatgtgaagtgttatttgcgtgtcgcgggcattatggcggagttctctcag
cctgacgatatgatggtggtttccgccgccggtagcaccactaaccagttgattaactgg
ttgaaactaagccagaccgatcgtctctctgcgcatcaggttcaacaaacgctgcgtcgc
tatcagtgcgatctgattagcggtctgctacccgctgaagaagccgatagcctcattagc
gcttttgtcagcgatcttgagcgcctggcggcgttgctcgacagtggtattaacgatgcg
gtgtatgcggaagtggtgggccacggtgaagtgtggtcggcgcgcctgatgtctgcggta
cttaatcaacaagggctgccagcggcctggcttgatgcccgtgagtttttacgcgctgaa
cgcgctgcgcaaccgcaggttgatgaagggctttcttacccgttgctgcaacagctactg
gtacaacatccgagcaaacgtctggtggtgaccgggtttatcagccgtaacaacgccggt
gaaacggtgttgctggggcgtaacggttccgactattccgcgacacaaatcggtgcgctg
gcgggtgtttctcgtgtaaccatctggagcgacgtcgccggggtatacagtgccgacccg
cgtaaagtgaaagatgcctgcctgctgccgttgctgcgtctggatgaggccagcgaactg
gcgcgtctggcggctcccgttcttcacgcccgtactttacagccagtttctggcagcgaa
atcgacctgcagctgcgctgtagctacacgccggatcaaggttccacgcgcattgaacgc
gtgctggcctccggtactggtgcgcgtattgtcaccagccacgatgatgtctgtttgatt
gagtttcaggtgcccgccagtcaggatttcaaactggcgcataaagagatcgaccagatc
ctgaaacgtgcccaggtgcgtccactggcggttggcgtgcataacgatcgccagttgttg
caattttgctacacctcagaagtggccgacagtgcgctgaaaatcctcgacgaagcggga
ttacctggagaactgcgcctgcgtcaggggctggcgctggtggcgatggtcggggcgggt
gtcacccgtaacccgctgcattgccaccgcttctggcagcaactgaaaggccagccggtc
gagtttacgtggcagtccgatgacggcatcagtctggtggcagtactgcgcaccggcccg
accgaaagcctgattcaggggctgcatcagtccgtcttccgcgcagaaaaacgcatcggc
ctggtattgttcggcaaaggcaatatcggctctcgctggctggaactgttcgcccgcgag
cagagcacgctttcggcgcgtaccggctttgaatttgtgctggcaggcgtggtggacagc
cgccgcagtctgttgagttatgacgggctggacgccagccgcgcgttagccttcttcaac
gatgaagcggtcgagcaggatgaagagtcgcttttcctgtggatgcgcgcccatccgtat
gatgatttagtggtgttggacgttaccgccagccagcagcttgctgatcagtatctcgat
ttcgccagccacggtttccacgtcatcagtgccaacaaactggcgggagcaagcgacagc
aataaatatcgccagatccacgacgccttcgaaaaaaccgggcgtcactggctatacaac
gccaccgttggtgcgggcttgccgatcaaccataccgtgcgcgatctgatcgacagcggc
gataccattttgtcgatcagtgggatcttctccggcacgctctcctggctgttcctgcaa
ttcgacggtagcgtgccgtttaccgagctggtggatcaggcgtggcagcagggcttaacc
gagcctgatccgcgtgacgacctctccggcaaagacgtaatgcgcaagctggtgattctg
gcgcgtgaagcgggttacaacattgaaccggaccaggtacgtgtggaatcgctggtgcct
gctcattgcgaaggcggcagcatcgaccatttctttgaaaatggcgatgaacttaacgag
cagatggtgcaacggctggaagcggcccgcgaaatggggctggtgctgcgctacgtggcg
cgtttcgatgccaacggcaaagcgcgtgtgggcgtggaggcggtgcgtgaagactatccg
ctggcatcactgctgccatgcgataacgtctttgccatcgaaagccgctggtaccgcgat
aatccgctggtgatccgtgggcctggcgctgggcgcgacgtcaccgccggggcgattcag
tcggatatcaaccggctggcacagttgttgtaa |
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