Shigella flexneri 2457T (serotype 2a): S0069
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Entry
S0069 CDS
T00128
Symbol
leuC
Name
(GenBank) 3-isopropylmalate isomerase (dehydratase) subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sfx
Shigella flexneri 2457T (serotype 2a)
Pathway
sfx00290
Valine, leucine and isoleucine biosynthesis
sfx00660
C5-Branched dibasic acid metabolism
sfx01100
Metabolic pathways
sfx01110
Biosynthesis of secondary metabolites
sfx01210
2-Oxocarboxylic acid metabolism
sfx01230
Biosynthesis of amino acids
Module
sfx_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sfx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
S0069 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
S0069 (leuC)
Enzymes [BR:
sfx01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
S0069 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
S0069 (leuC)
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GFIT
Motif
Pfam:
Aconitase
Spo0M
Motif
Other DBs
NCBI-ProteinID:
AAP15613
UniProt:
Q821C2
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Position
complement(76792..78192)
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AA seq
466 aa
AA seq
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MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFAT
MDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLP
GMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITA
KDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAALVAPDETTF
NYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISV
NDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAE
IAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNP
GERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atggctaaaacgttatacgaaaaattattcgacgctcacgtagtgtacgaagccgaaaac
gaaaccccgctgttatatatcgaccgccacctggtgcatgaagtgacctcaccgcaggcg
ttcgatggtctgcgcgcccacggtcgcccggtacgtcagccgggcaaaaccttcgccact
atggatcacaacgtctctacccagaccaaagacattaatgcctgtggtgaaatggcgcgc
atccagatgcaggagctgattaaaaactgcaaagaatttggcgtcgagctgtatgacctg
aatcacccgtatcaggggatcgtccacgtaatggggccggaacagggcgtcaccttgccg
gggatgaccattgtctgcggcgactcgcataccgccacccacggcgcgtttggcgcactg
gcctttggtatcggcacttccgaagttgaacacgtactggcaacacaaaccctgaaacag
ggccgtgcgaagaccatgaaaattgaagtccagggcaaagccgcgccgggcattaccgca
aaagatatcgtgctggcaattatcggtaaaactggcagcgcaggcggcaccgggcatgtg
gtggagttttgcggcgaagcaattcgtgatttaagcatggaaggtcgtatgaccctgtgc
aatatggcgatcgaaatgggcgcaaaagccgctctggttgctcctgacgaaaccaccttt
aactatgtcaaaggccgtctgcatgcgccgaaaggcaaagatttcgacgacgccgttgcc
tactggaaaaccctgcaaaccgacgaaggcgcaactttcgataccgttgtcactctgcaa
gcagaagaaatttcaccgcaggtcacctggggcaccaatcccggccaggtgatttctgtg
aacgacaatattcccgatccggcttcgtttgccgatccggttgaacgtgcgtcggcagaa
aaagcgctggcctatatggggctgaaaccgggtattccgctgaccgaagtggctatcgac
aaagtgtttatcggttcctgtaccaactctcgcattgaagatttacgcgcggcagcggag
atcgccaaagggcgaaaagtcgcgccaggcgtgcaggcactggtggttcccggctctggc
ccggtaaaagcccaggcggaagcggaaggtctggataaaatatttattgaagccggtttt
gaatggcgcttgcctggctgctcaatgtgtctggcgatgaacaacgaccgtctgaatccg
ggcgaacgttgtgcatccaccagcaaccgtaactttgaaggccgccaggggcgcggcggg
cgcacgcatctggtcagcccggcaatggctgccgctgctgctgtgaccggacatttcgcc
gacattcgcaacattaaataa
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