Streptomyces galilaeus: CP966_20860
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Entry
CP966_20860 CDS
T06932
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sgal
Streptomyces galilaeus
Pathway
sgal00860
Porphyrin metabolism
sgal01100
Metabolic pathways
sgal01110
Biosynthesis of secondary metabolites
sgal01120
Microbial metabolism in diverse environments
sgal01240
Biosynthesis of cofactors
Module
sgal_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sgal_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sgal00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CP966_20860
Enzymes [BR:
sgal01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CP966_20860
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CP966_20860
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QEU67414
UniProt:
A0A5J6EV00
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Position
4560146..4561849
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AA seq
567 aa
AA seq
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MSPTTLPAGPEHGHVTFLGAGPGDPGLLTLRAVEALANADVLVAEHEVLDVVRTHARPGV
AVVHTEAGPFPGPLPGTGTPHPTIVDGTSTTAGSPAVRDAAHLVMEAARGGRRVVRAVSG
DPGLDTYAAEEMLACVAAGVPFEVVPGISAAVGVPAYAGVPLRDAQGADVRFIDARTASD
RCWTEVGVSDGTVVVSTTLDSVAAAAGELVAAGRKPDTPMTVTVAGTTTRQRTWCATLGT
IAQTLKQAKVLPSPEGGRPVIAVVGERSAPAQRDQLAWFESKPLFGWKVLVPRTKEQAAS
LSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFE
EYGLDARAFAGIKVAAVGEATAQALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPID
RVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSS
STVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALAEFGLRR
RAAAREAGDAVSRPSERRPGARRRRAT
NT seq
1704 nt
NT seq
+upstream
nt +downstream
nt
gtgagccccaccacacttcccgccggtcctgaacacgggcacgtcaccttccttggtgcc
ggacccggggatccgggactgctgactcttcgcgccgtggaggcgctggcgaacgcggac
gtcctcgtcgccgagcacgaggtgctcgacgtcgtccggacgcacgccaggccaggcgtc
gccgtcgtgcatacggaagccggtccgttcccgggccctcttccgggcacgggcacgccg
cacccgacgatcgttgacggcacgtcaacaaccgctgggagccccgctgtgcgggatgcc
gcacatcttgtcatggaggccgcacggggcggcaggcgggtcgtccgtgcggtgtccggg
gacccgggacttgatacgtacgcggccgaggaaatgctcgcctgtgtcgccgccggtgtt
cccttcgaggtcgtccccggcatctcggccgccgtcggcgtgcccgcgtacgccggtgtg
ccgctgcgcgacgcgcagggcgcggacgtccggttcatcgacgcgcggaccgcgtccgac
cggtgctggaccgaggtcggcgtgtccgacgggaccgtcgtcgtgtccacgacgctggac
tccgtggccgcggccgccggcgaactggtcgcggccgggcgcaagcccgacaccccgatg
accgtcaccgtcgccggtacgacgacccgtcagcggacctggtgcgccaccctcggcacc
atcgcgcagacgctgaagcaggcgaaggtgctgccctctcccgagggcggccgaccggtc
atagccgtggtcggtgagcgttccgctcccgcgcagcgcgaccagctggcctggttcgag
tcgaagccgctgttcggctggaaggtgctcgtgccgcgcaccaaggagcaggcggcctca
ctctccgaccagctgcggtcctacggggccgtgccgcacgaggtgccgaccatcgccgtc
gaaccgccgcggacgccccaacagatggagcgggcggtgaaggggctcgtcaccggtcgg
tacgagtggatcgccttcacctccgtcaacgccgtcaaggccgtgcgggagaagttcgag
gagtacgggctcgacgcccgcgccttcgccgggatcaaggtcgcggcggtgggggaagcc
accgcccaggcgctgatcgcgttcggtgtgaagccggacctggtgccgagcggggagcag
tccgcggccgggctgctggaggactggcctccctacgacccggtgttcgatccgatcgac
cgggtgttcctgccgcgggccgacatcgccaccgagacgctcgtcgccgggctcatcgag
ctgggctgggaggtcgacgacgtcacggcctaccggaccgtgcgggcctcgccgccgccg
gccgagacgcgtgaggcgatcaagggcggcgggttcgacgccgtgctgttcacgtcgtcg
tccaccgtgcgcaacctggtcgggatcgccgggaagccgcacaacgtgacggtcatcgcg
tgtatcgggccggctacggccaagacggccgaggagcacgggcttcgggtggacgtgatg
gctcccgagccgtccgtgcacaagctggccgaggcgctggcggagttcgggctgcggcgg
agggctgcggcgcgggaggccggggacgcggtcagtcggcctagcgagcggcggccgggg
gctcggcggcgtcgggccacctga
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