Streptomyces globisporus: WQO_14795
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Entry
WQO_14795 CDS
T04209
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sgb
Streptomyces globisporus
Pathway
sgb00860
Porphyrin metabolism
sgb01100
Metabolic pathways
sgb01110
Biosynthesis of secondary metabolites
sgb01120
Microbial metabolism in diverse environments
sgb01240
Biosynthesis of cofactors
Module
sgb_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
sgb_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sgb_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sgb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
WQO_14795
Enzymes [BR:
sgb01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
WQO_14795
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
WQO_14795
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
ALU94501
UniProt:
A0A0U3BXY0
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Position
complement(3439708..3441378)
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AA seq
556 aa
AA seq
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MSPTGPAASDFPVLSAQGQVTFLGAGPGDPGLLTLRAVEALASADVLVAEPDVLDVVRSH
AREGVSTPELTLVDVSSTSAGVPVLRDAANLVMEAAKGGRRVVRAVAGDPGLDGDAGAEM
LACAAAGVPFEVVPGIANAVGVPAYAGVPLRDAHGADVRFVDARTASDRCWSEVGASDAT
AVVSTTLDSVAAAAGELVSAGRKPDTPLTVTIAGTTTRQRTWTATLGTIAQTLKQAKVLP
SPEGHRPVIAVVGERSSAAQRDQLAWFESKPLFGWRVLVPRTKEQAASLSDQLRSYGAVP
HEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGI
KVAAVGEQTAAALIDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATE
TLVAGLIELGWEVDDVTAYRTVRASPPPADTREAIKGGGFDAVLFTSSSTVRNLVGIAGK
PHNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVHKLAEALAAFGAQRRDAAKEAGDPVT
RPSERRPGARRRRTTT
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccggccccgccgcatccgactttccggtcctgtccgcccaaggccaggtc
accttcctcggcgccggtcccggcgacccgggactgctgactctgcgcgctgtcgaagcg
ctcgcgagcgcggacgtccttgtcgccgagcccgatgtgctcgacgtcgttcgcagccat
gcgcgggaaggcgtgagcacgcctgagctgacgcttgttgacgtctcgtcaacaagcgcc
ggtgtacccgttctcagggatgcggccaatcttgtcatggaggccgcgaagggcggcagg
cgggtggtccgtgccgtcgcgggcgatccgggtctggacggcgacgcgggcgcggagatg
ctcgcctgcgccgccgccggggtgcccttcgaggtggtcccgggcatcgcgaacgccgtc
ggcgtgcccgcgtacgccggggtgccgctccgcgacgcgcatggcgcggacgtccgcttc
gtcgacgcccgtacggcctccgaccggtgctggagcgaggtcggcgcgagcgacgccacc
gccgtcgtctccaccacgctggactcggtggcggccgccgccggtgagctggtctcggcg
ggccgcaagcccgacaccccgctcaccgtgacgatcgcgggcaccaccacccgccagcgc
acctggacggcgaccctcgggacgatcgcccagaccctcaagcaggccaaggtgctcccc
tcgcccgagggccaccggccggtcatagcagtggtcggagagcgcagctccgccgcacag
cgcgaccagctcgcgtggttcgagtccaagccgctgttcggctggcgggtgctcgtcccg
cggaccaaggagcaggccgcgtcgctctccgaccagctgcgctcctacggtgcggtgccg
cacgaggtcccgacgatcgccgtcgagccgccgcgtacgccccagcagatggagcgcgcg
gtcaagggcctggtcaccggccgctacgagtggatcgccttcaccagcgtgaacgccgtc
aaggcggtccgggagaagttcgaggagtacggtctcgacgcccgggccttcgccgggatc
aaggtcgccgccgtcggcgagcagaccgccgccgcgctgatcgacttcggcgtcaagccg
gacctggtgccctccggcgagcagtccgccgccgggctgctggaggactggccgccctac
gacccggtcttcgacccgatcgaccgggtgttcctgccgcgcgccgacatcgccaccgag
accctggtggccgggctcatcgagctgggctgggaggtcgacgacgtcaccgcgtaccgc
acggtccgcgcctcgccgccgccggccgacacccgcgaggcgatcaagggcggcggcttc
gacgcggtcctgttcacctcgtcctcgacggtgcgcaacctggtcggcatcgcgggcaag
ccgcacaacgtgaccgtgatcgcgtgtatcggcccggccaccgcgaagaccgccgaggag
cacggtctgcgggtggacgtcctgtccccggagccgtcggtgcacaagctcgccgaggcg
ctcgccgccttcggcgcgcagcgccgggacgccgcgaaggaggccggcgacccggtgacc
cggccgagcgagcgccgcccgggggcgcgcaggcgtcggacgacgacctaa
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