Streptomyces griseorubiginosus: DWG14_03700
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Entry
DWG14_03700 CDS
T06099
Symbol
nasF
Name
(GenBank) Uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sge
Streptomyces griseorubiginosus
Pathway
sge00860
Porphyrin metabolism
sge01100
Metabolic pathways
sge01110
Biosynthesis of secondary metabolites
sge01120
Microbial metabolism in diverse environments
sge01240
Biosynthesis of cofactors
Module
sge_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sge_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sge00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
DWG14_03700 (nasF)
Enzymes [BR:
sge01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
DWG14_03700 (nasF)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
DWG14_03700 (nasF)
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AYC39463
UniProt:
A0A385ZKN1
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Position
complement(4226382..4228088)
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AA seq
568 aa
AA seq
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MSPTTLPAGPEHGHVTFLGAGPGDPGLLTLRAVEALTNADVLVAGHEVLDVVRAHARSGV
AVVNTDTESPSAPVPGTGAPQLTVVDSTSTTAPAPAVRDAAHLVMEAARGGRRVVRAVSG
DPGLDAYAAEEMLACARAGVPFEVVPGVAAAVGVPAYAGVPLRDAHGADVRFVDARTASD
RCWTEVGASDGTVVVSTSLDSVGAAAGELVAAGRKPDTPMTVTVAGTTTRQRTWTATLGT
IAQTLKQAKVLPSPEGGRPVIAVVGERSAAAQREQLSWFESKPLFGWRVLVPRTKEQAAS
LSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFE
EYGLDARAFAGIKVAAVGEQTAKALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPID
RVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSS
STVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHRLAEALADFGLKR
RAAAVEAGDPVTRPSERRPGARRRRSTT
NT seq
1707 nt
NT seq
+upstream
nt +downstream
nt
gtgagccccaccacccttcccgccggtcctgaacacgggcacgtcaccttcctcggtgcc
ggacccggagatccgggactgctgactctgcgcgccgtggaggcgctcacgaacgcggac
gtcctcgtcgccgggcacgaagtgctcgacgtcgtgcgcgcccacgctcggtcgggcgtc
gccgtcgtgaacacggacacggagtcgccttcggctccggttccgggcacgggcgcgccc
caactgacagttgttgacagcacgtcaacaaccgcccctgcccccgctgtacgggatgcg
gcacatcttgtcatggaggccgcgcggggcggcaggcgggtcgtacgtgcggtgtccggg
gaccccgggctcgacgcgtacgccgccgaggagatgctggcctgcgcccgcgcgggcgtg
ccgttcgaggtcgtgcccggtgtcgccgcggccgtcggcgtgcccgcgtacgccggtgtg
ccgctgcgggacgcgcacggcgcggacgtgcggttcgtcgacgcgcgcacggcctccgac
cggtgctggacggaggtgggggcgtccgacgggaccgtggtcgtgtcgacgtccctggac
tccgtcggcgccgccgccggtgagctggtcgcggccggccgtaagcccgacaccccgatg
acggtcaccgtcgccggtacgacgacccggcagcggacctggacggcgaccctgggcacc
atcgcccagacgctcaagcaggccaaggtgctgccctcgcccgagggcgggcggccggtg
atagccgtggtcggtgagcggtccgccgcggctcagcgcgagcagttgtcgtggttcgag
tccaagccgctgttcgggtggcgggtgctcgtgccgcgtacgaaggagcaggcggcgtcg
ctctccgaccagctgcggtcctacggggccgtgccgcacgaggtgccgacgatcgccgtc
gagccgccgcggactccgcagcagatggagcgggcggtcaaggggctcgtcaccgggcgc
tacgagtggatcgcgttcacctcggtcaacgcggtgaaggcggtgcgggagaagttcgag
gagtacgggctcgatgcccgggccttcgcggggatcaaggtcgccgcggtgggggagcag
acggcgaaggcgttgatcgcgttcggtgtgaagccggatctcgtgccgagcggtgagcag
tcggccgcggggctccttgaggactggccgccgtacgaccctgtcttcgacccgatcgac
cgggtgttcctgccgcgggccgacatcgccacggagacgctggtcgccgggctgatcgag
ctcgggtgggaggtcgacgacgtcaccgcgtaccggaccgtgcgggcgtcgccgccgccg
gcggagacgcgggaggcgatcaaggggggcgggttcgatgccgtgctcttcacgtcgtcg
tccacggtgcggaacctggtgggtatcgcggggaagccgcacaacgtgaccgtgatcgcg
tgtattggtcctgctacggcgaagaccgctgaggagcacgggctgcgggtcgatgtgatg
gctcctgagccgtccgtgcaccggctggccgaggcgctcgcggacttcgggctgaagcgg
cgggcggcggcggtggaggcgggcgatccggtgacgcggccgagtgagcggcggccgggg
gcgcggcgtcggcggtcgacgacctga
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