Streptomyces griseofuscus: HEP81_02481
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Entry
HEP81_02481 CDS
T07010
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sgf
Streptomyces griseofuscus
Pathway
sgf00290
Valine, leucine and isoleucine biosynthesis
sgf00660
C5-Branched dibasic acid metabolism
sgf01100
Metabolic pathways
sgf01110
Biosynthesis of secondary metabolites
sgf01210
2-Oxocarboxylic acid metabolism
sgf01230
Biosynthesis of amino acids
Module
sgf_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sgf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
HEP81_02481 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
HEP81_02481 (leuC)
Enzymes [BR:
sgf01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
HEP81_02481 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
HEP81_02481 (leuC)
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GFIT
Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
QNT92803
UniProt:
A0A7H1PXM3
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Position
complement(2826051..2827475)
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRAQGEPDLLYIDLHLLHEVTSPQAFDGLRQNGRQVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPMARPKTMAITVDGELPEGVSA
KDLILAIIARIGTGGGQGYILEYRGSAIERLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLKGRPHAPEGAEWDAAVEYWKTLRTDEDAEFDAEVVIDAAALSPFVTWGTNPGQGAPL
SADVPDPASYEDASERLAAEKALEYMGLEAGAPLRSIKVDTVFVGSCTNGRIEDLRTVAE
ILKDRKVADGVRMLVVPGSARVGLQAAAEGLDVVFKEAGAEWRYAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLTDDRTPAGV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggaaaaggtctgggacgaccacgtcgtccggcgcgcccagggc
gagcccgacctcctctacatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacgggctgcgccagaacggccgccaggtgcgccgcctcgacctcaccatcgcgacc
gaggaccacaacacccccaccctcgacatcgacaagcccatcgccgacccggtctcgcgc
gcccagctggagacgctgcgcaagaactgcgccgagttcggggtgcggctgcacccgctg
ggcgacgtcgagcagggcgtcgtgcacgtggtcggcccccagctgggcctgacccagccc
ggtacgaccgtggtgtgcggcgactcccacacgtccacgcacggcgcgttcggcgcgctg
gcgttcggcatcggcacctcccaggtcgagcatgtgctggccacccagacgctgccgatg
gcccgcccgaagaccatggcgatcaccgtggacggcgaactgcccgagggcgtcagcgcc
aaggacctgatcctggcgatcatcgcgcggatcggcaccggcggcggccagggctacatc
ctggagtaccgcggctccgccatcgagaggctctcgatggaggcccggatgaccatctgc
aacatgtcgatcgaggcgggcgcccgcgcgggcatgatcgcccccgacgagaccaccttc
gcgtacctcaagggccgcccgcacgcccccgagggcgccgagtgggacgcggccgtcgag
tactggaagacgctgcgcacggacgaggacgcggaattcgacgccgaggtcgtcatcgac
gccgccgcgctgtccccgttcgtcacctggggcaccaaccccggccagggtgcgccgctt
tcggcggacgtccccgatccggcttcgtacgaagacgcatcggagcgcctggccgccgaa
aaggccctggaatacatggggttggaggccggagcgccgctgcgctccatcaaggtggac
accgtcttcgtaggctcgtgcaccaacggccggatcgaggatctgcgcactgtcgccgag
atcctgaaggaccgcaaagtcgccgacggcgtacggatgctggtcgtgccgggctccgcg
cgggtcggcctccaggcggccgccgagggtctggacgtggtcttcaaggaggccggcgcc
gagtggcggtacgcgggctgctcgatgtgcctgggcatgaacccggaccagctggccccg
ggggagcgctccgcgtccacctccaaccgcaacttcgagggccggcagggcaagggcggt
cgtacccacctggtgtcgccgcaggtcgcggcggccaccgccgtcctgggccatctggcc
tccccggccgacctgaccgacgaccgtacgcccgctggagtctga
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