Streptomyces genisteinicus: IAG43_17925
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Entry
IAG43_17925 CDS
T07903
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sgj
Streptomyces genisteinicus
Pathway
sgj00860
Porphyrin metabolism
sgj01100
Metabolic pathways
sgj01110
Biosynthesis of secondary metabolites
sgj01120
Microbial metabolism in diverse environments
sgj01240
Biosynthesis of cofactors
Module
sgj_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sgj_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sgj00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
IAG43_17925
Enzymes [BR:
sgj01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
IAG43_17925
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
IAG43_17925
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QNP64605
UniProt:
A0A7H0HVN9
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Position
4119418..4121079
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AA seq
553 aa
AA seq
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MSPTTSNHPALPAHGHVTFLGAGPGDPGLLTLRAVEALSGADVLVAEPAVLEVVRAHARA
GVSTPELTVVDDASVSAGIPVLRDAANLVMEAARGGKRVVRAVTGDPGLDTDTGREMLAC
AAAGIPFEVVPGVATAVGVPAYAGVPLRDAEGADVRFVDARTASDRCWTEVGASDGTAVV
STTLDSVAAAAGEMVAAGRKPDTPLTVTIAGTTTRQRTWTATLGTIAQTLKQAKVLPSPE
GHQPVIAVVGERSAAAQRDQLAWFESKPLFGWKVLVPRTKEQAASLSDQLRSYGAVPHEV
PTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKVA
AVGEQTAAALVDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATETLV
AGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHN
VTVIACIGPATAKTAEEHGLRVDVLSPEPSVHRLAEALAEFGAARRAAAVEAGEHVTRPS
ERRPGGRRRRTTT
NT seq
1662 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccacctcgaaccatccggccctcccggcacacgggcacgtcaccttcctg
ggcgccggtcccggcgaccccggtctgctgaccctgcgcgccgtggaggccctctccggc
gcggacgtcctggtcgccgaacccgctgtgctggaggtcgtccgcgctcatgcccgggcg
ggcgtaagcacgcctgagctgacggtggttgacgacgcgtcagtgtccgccggcatcccc
gttctcagggacgcggccaatcttgtcatggaggccgcacggggcggcaagcgggtcgtg
cgtgccgtcacgggggacccgggcctggacacggacacggggcgggagatgctcgcctgc
gccgccgcgggcatccccttcgaggtcgtgccgggtgtcgcgaccgccgtcggcgtgccc
gcgtacgccggtgtcccgctgcgggacgcggagggcgccgacgtccggttcgtcgacgcc
cgcacggcgtccgaccgctgctggaccgaggtcggggcgagcgacggcaccgccgtcgtc
tccaccacgctcgactcggtcgccgcggcggcgggcgagatggtggcggccggccgcaag
ccggacaccccgctgacggtcacgatcgccggcaccaccacccgccagcggacctggacg
gcgacgctcgggaccatcgcgcagaccctgaagcaggcgaaggtgctgccctcgccggaa
gggcaccagccggtcatagccgtcgtcggcgaacgcagcgccgcggcccagcgcgaccag
ctcgcctggttcgagtccaagccgctcttcggctggaaggtgctggtgccgcgcaccaag
gagcaggcggcctcgctctccgaccagctgcgttcctacggcgcggtcccgcacgaggtc
ccgaccatcgcggtcgagcccccgcgcacgccccagcagatggagcgcgccgtcaagggc
ctggtcaccggccgctacgagtggatcgcgttcacctcggtcaacgccgtcaaggcggtg
cgggagaagttcgaggagtacgggctcgacgcgcgcgccttcgccggcatcaaggtggcg
gcggtcggcgagcagacggcggcggcgctggtcgacttcggcgtcaagccggacctggtc
ccgagcggcgagcagtccgcggccgggctcttggaggactggccgccctacgacccggtc
ttcgacccgatcgaccgcgtcttcctgccgcgtgccgacatcgcgaccgagacgctggtc
gccggactgatcgaactcgggtgggaggtcgacgacgtcaccgcctaccggaccgtccgc
gcctcgccgccgccggccgagacccgcgaggcgatcaagggcggcgggttcgacgcggtg
ctcttcacctcctcgtcgaccgtgcggaacctcgtcggcatcgccggcaagccgcacaac
gtgaccgtgatcgcgtgcatcggcccggcgaccgcgaagacggcggaggagcacggcctg
cgggtcgacgtcctgtcgccggagccgtcggtgcaccgcctcgccgaggccctggcggag
ttcggcgccgcacgccgcgccgcggccgtggaggccggcgagcacgtgacccggccgtcg
gagcggcgtccgggtgggcggaggcgtcgcacgacgacgtga
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