Streptomyces genisteinicus: IAG43_22965
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Entry
IAG43_22965 CDS
T07903
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sgj
Streptomyces genisteinicus
Pathway
sgj00290
Valine, leucine and isoleucine biosynthesis
sgj00660
C5-Branched dibasic acid metabolism
sgj01100
Metabolic pathways
sgj01110
Biosynthesis of secondary metabolites
sgj01210
2-Oxocarboxylic acid metabolism
sgj01230
Biosynthesis of amino acids
Module
sgj_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sgj00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
IAG43_22965 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
IAG43_22965 (leuC)
Enzymes [BR:
sgj01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
IAG43_22965 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
IAG43_22965 (leuC)
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Motif
Pfam:
Aconitase
DUF4946
AcnX
Motif
Other DBs
NCBI-ProteinID:
QNP65504
UniProt:
A0A7H0HY88
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All DBs
Position
5272492..5273922
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AA seq
476 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRLSGRQVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHSLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPMARPKTMAITVDGELPDGVTA
KDLILAIIARIGTGGGQGYVLEYRGSAVEKLSMEARMTICNMSIEAGARAGMIAPDETTF
DYLRGRDHAPQGEDWDAAVAYWRTLRTDDDAVFDAEVFIDAAELSPFVTWGTNPGQGAPL
GANVPDPASYEDASERLAAEKALEYMGLTAGQPLRDIRVDTVFVGSCTNGRIEDLRAVAS
ILEGRKVADGVRMLVVPGSVRVALQAVEEGLDKVFKAAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAGATAVLGHLASPADLSDADVSTPAGV
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccacgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccccaggcg
ttcgacggtctgcggctcagcggtcggcaggtgcggcgtctcgacctcaccatcgccacc
gaggaccacaacaccccgaccctcgacatcgacaagcccatcgccgacccggtctcccgc
gcccagctggagaccctgcgcaagaactgcgccgagttcggtgtgcgcctgcactcgctg
ggcgacgtcgagcagggcgtggtccacgtggtcggcccccagctgggcctgacccagccc
ggcaccaccgtggtctgcggcgactcccacacctccacccacggcgccttcggcgcgctg
gcgttcggcatcggcacctcccaggtggagcacgtgctggccacccagacgctgccgatg
gcccgcccgaagaccatggccatcaccgtcgacggcgaactgccggacggcgtgacggcc
aaggacctgatcctggcgatcatcgccaggatcggcaccggcggcggacagggctacgtc
ctggagtaccgcggctccgccgtcgagaagctctcgatggaagcccggatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgccccggacgagaccaccttc
gactacctccggggccgcgaccacgccccgcagggcgaggactgggacgccgccgtcgcg
tactggcgcaccctgcgcaccgacgacgacgcggtcttcgacgccgaggtgttcatcgac
gccgccgagctctccccgttcgtcacctggggcaccaacccgggccagggcgcaccgctc
ggggcgaacgtccccgacccggcttcgtacgaggacgcctcggagcgcctggcggccgaa
aaggccctggagtacatggggttgaccgccgggcagccgctgcgggacatccgcgtcgac
accgtcttcgtcggttcctgcaccaacggacgcatcgaggacctgcgcgcggtcgcctcg
atcctcgaaggccgcaaagtcgccgacggcgtgcggatgctggtcgtcccgggatccgtc
cgggtggcgctccaggccgtggaggagggcctggacaaggtcttcaaggcggcgggcgcc
gagtggcggcacgcgggctgctccatgtgcctcggcatgaacccggaccaactggctccc
ggcgagcgctccgcctccacctccaaccgcaacttcgagggcaggcagggcaagggcggc
cgcacccacctggtctctccgcaggtcgccggcgccaccgccgtgctgggccatctggcc
tccccggccgacctgtccgacgccgacgtctctacgcccgcgggggtctga
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