Streptomyces gardneri: H4W23_17905
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Entry
H4W23_17905 CDS
T07252
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sgx
Streptomyces gardneri
Pathway
sgx00860
Porphyrin metabolism
sgx01100
Metabolic pathways
sgx01110
Biosynthesis of secondary metabolites
sgx01120
Microbial metabolism in diverse environments
sgx01240
Biosynthesis of cofactors
Module
sgx_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
sgx_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sgx_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sgx00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
H4W23_17905
Enzymes [BR:
sgx01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
H4W23_17905
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
H4W23_17905
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QPK46317
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Position
complement(3986271..3987941)
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AA seq
556 aa
AA seq
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MNPTRPTTSPVSSAFTGHGHVTFLGAGPGDPGLLTLRAVEALAGADVLIAEPEVLEVVRD
HARAGVSTPELTVVDEASTAAGVPVLRDAANLVMEAARGGRRVVRAVTGDPGLDGNAGAE
MLACAAEGIPFEVVPGVATAVGVPAYAGVPLRDAQGTDVRFVDARTADERCWAEVGASDG
TVVVSTSLDSVAAAAGELVAAGRKPDTPLTVTIAGTTTRQRTWTATLGTIAQVFKQGKIL
PSPEGHRPVIAVVGERSAPAQRDQLSWFESKPLFGWRVLVPRTKEQAASLSDQLRSYGAV
PHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAG
IKVAAVGEQTAAALVDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIAT
ETLVAGLIELGWEVDDVTAYRTVRASPPPADTREAIKGGGFDAVLFTSSSTVRNLVGIAG
KPHNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVHKLAEALADFGLRRREAALEAGDPV
TRPSERRPGARRRRTT
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
ttgaaccccacccgcccgaccaccagccctgtgtcctcggccttcaccggccacgggcac
gtcacgttcctcggcgcaggaccgggagaccccggactgctgaccctcagggccgtcgag
gccctcgcgggcgcggacgtcctgatcgccgagccggaggtgctcgaggtcgttcgcgac
catgcgcgtgcgggggtgagcacgcctgagctgacggttgttgacgaggcgtcaacagcc
gccggagtccccgtgttgagggatgccgccaatcttgtcatggaggccgcgaggggcggc
aggcgggtcgtccgtgcggtgaccggcgaccccggtctcgacgggaacgcgggagccgag
atgctcgcctgcgccgccgagggcatccccttcgaggtcgtccccggtgtcgccaccgcc
gtcggcgtgcccgcctacgccggcgtcccgctgcgtgacgcgcagggcacggacgtgcgg
ttcgtcgacgccaggaccgccgacgagcggtgctgggccgaggtcggtgcctccgacgga
accgtcgtcgtgtccacctcgctcgactcggtggccgcggctgccggtgaactggtggcg
gcaggccgtaagccggacaccccgctcaccgtcacgatcgcgggcacgaccacccggcag
cggacctggaccgcgacgctcggcacgatcgcccaggtcttcaagcagggcaagatcctc
ccctcgcccgagggccaccgacccgtcatagccgtggtcggcgagcgcagcgccccggcg
cagcgggaccagctgtcgtggttcgagtcgaagccgctcttcgggtggcgggtgctcgtg
ccgcgtaccaaggagcaggccgcctcgctctccgaccagctgcgttcgtacggcgcggtg
ccgcacgaggtgccgacgatcgccgtcgagccgccgcggaccccgcagcagatggagcgg
gccgtcaaggggctcgtcaccggacggtacgagtggatcgccttcacctcggtgaacgcg
gtgaaggccgtacgggagaagttcgaggagtacgggctcgacgcgcgcgccttcgccggg
atcaaggtcgcggcggtgggcgagcagaccgcggcggcgctggtcgacttcggtgtgaag
ccggatctcgtgccgagtggtgagcagtcggcggcgggtctgttggaggactggccgccg
tacgaccccgtcttcgacccgatcgaccgcgtcttcctgccgcgggccgacatcgcgacc
gagacgctggtcgcgggcctgatcgagctcgggtgggaggtcgacgacgtcaccgcctac
cggaccgtacgggcttcgccgccgccggcggacacgcgggaggcgatcaagggcggtggg
ttcgatgccgttctcttcacgtcgtcttctaccgtgcggaacctggtcgggatcgccggg
aagccgcacaacgtgacggtgatcgcgtgcatcggtcccgctacggccaagacggccgag
gagcacgggctgcgggtggacgtgctgtcgcccgagccgtccgtgcacaagctggcggag
gcgctggcggacttcgggctgcggcggcgtgaggctgcgctggaggccggggatccggtg
acgcggccgagtgagcggcggccgggggcgcggaggcggcggaccacgtag
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