KEGG   Streptomyces globosus: C0216_02155
Entry
C0216_02155       CDS       T06864                                 
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
  KO
K13542  uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
Organism
sgz  Streptomyces globosus
Pathway
sgz00860  Porphyrin metabolism
sgz01100  Metabolic pathways
sgz01110  Biosynthesis of secondary metabolites
sgz01120  Microbial metabolism in diverse environments
sgz01240  Biosynthesis of cofactors
Module
sgz_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
sgz_M00926  Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:sgz00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    C0216_02155
Enzymes [BR:sgz01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     C0216_02155
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.75  uroporphyrinogen-III synthase
     C0216_02155
SSDB
Motif
Pfam: HEM4 TP_methylase
Other DBs
NCBI-ProteinID: AXE22401
UniProt: A0A344TUT0
LinkDB
Position
455827..457497
AA seq 556 aa
MNPSRPTTSALPVAAAGHGHVTFLGAGPGDPGLLTLRAVEALAAADVLIAEPEVLEVVRT
HARAGVDTPQLTIADEASAAAGVPVIRDAANLVMEAARSGKRVVRAVTGDPGLDGNAASE
MLACAGEGIPFEVVPGVATAVGVPAYAGVPLRGEQGADVRFVDARNASAQCWSEVGSGHG
VVVVSATLETVPAACAELVAAGRAGDTPLTVTVGGTTTRQRTWNATLGTIAQVFKQGKVL
PSPEGTRPVIAVVGEQGAAARREELAWFESKPLFGWRVLVPRTKEQAASLSDQLRSYGAV
PHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAG
IKVAAVGEQTAAALVEFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIAT
ETLVAGLIELGWEVDDVTAYRTVRASPPPADTREAIKGGGFDAVLFTSSSTVRNLVGIAG
KPHNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVGKLAEALAEYGAARREAAKEAGESV
SRPSERRPGARRRRTT
NT seq 1671 nt   +upstreamnt  +downstreamnt
ttgaacccctcacgtcccaccacctccgctctccccgtcgccgccgccgggcacgggcac
gtcaccttcctcggtgcgggccccggcgacccgggactgctgacgctgcgcgccgtcgag
gcgctcgccgccgcggatgtgctcatcgcggagcccgaggtgctcgaggtcgtccgcacg
cacgcgcgcgccggagtggacacgccacagctgacgatcgctgacgaggcgtcagcggcc
gccggagtaccggtgatccgggacgccgccaatcttgtcatggaggccgcgcgctccggc
aagcgggtcgtccgtgccgtcaccggcgaccccggcctcgacggcaacgccgcctccgaa
atgctcgcctgcgccggcgagggcatccccttcgaggtcgtgcccggcgtcgccaccgcc
gtcggcgtccccgcctacgcgggcgtcccgctgcgcggcgaacagggcgccgacgtccgc
ttcgtcgacgcccgcaacgcctccgcgcagtgctggagcgaggtcggctccggccacggc
gtcgtcgtcgtctccgccaccctggagaccgtccccgccgcctgcgccgagctcgtcgcc
gccggccgcgccggcgacaccccgctcaccgtcaccgtcggcggcaccaccacccgccag
cggacctggaacgccaccctcggcaccatcgcccaggtcttcaagcagggcaaggtcctg
ccctcccccgagggcacccgcccggtgatagccgtcgtcggcgagcagggcgccgccgcc
cgccgcgaggagctcgcctggttcgagtcgaagccgctgttcggctggcgggtgctcgtc
ccccgcaccaaggagcaggccgcctccctctccgaccagctccgctcctacggcgccgtg
ccgcacgaggtccccaccatcgccgtggagccgccgcgcaccccgcagcagatggagcgc
gccgtcaagggcctcgtcaccggccgctacgagtggatcgccttcacctcggtgaacgcc
gtcaaggcggtacgcgagaagttcgaggagtacgggctcgacgcgcgcgccttcgccggc
atcaaggtcgcagcggtgggggagcagaccgccgccgccctcgtcgagttcggcgtcaag
cccgacctcgtgccgagcggcgagcagtccgccgccggactgctggaggactggccgccg
tacgacccggtcttcgacccgatcgaccgcgtcttcctgccgcgcgccgacatcgccacc
gagaccctcgtcgccgggctgatagagctcggttgggaggtcgacgacgtcaccgcctac
cggaccgtgcgcgcctcgcccccgccggcggacacgcgcgaggcgatcaagggcggcggc
ttcgacgccgtgctcttcacctcgtcctcgacggtgcgcaacctcgtcggcatcgccggc
aagccgcacaacgtcaccgtcatcgcctgcatcggcccggcgaccgccaagaccgccgag
gagcacggcctccgcgtcgacgtcctgtcgccggagccgagcgtgggcaagctcgccgaa
gccctcgccgagtacggcgcggcgcgccgcgaggccgccaaggaggccggcgagtcggtg
tcccggccgagcgagcgccggccgggggcgcggcggcgccggacgacctga

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