Streptomyces harbinensis: HUT13_15645
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Entry
HUT13_15645 CDS
T07389
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
shar
Streptomyces harbinensis
Pathway
shar00860
Porphyrin metabolism
shar01100
Metabolic pathways
shar01110
Biosynthesis of secondary metabolites
shar01120
Microbial metabolism in diverse environments
shar01240
Biosynthesis of cofactors
Module
shar_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
shar_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
shar00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
HUT13_15645
Enzymes [BR:
shar01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
HUT13_15645
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
HUT13_15645
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GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
QKV70042
UniProt:
A0A1I6WBV8
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Position
3460452..3462110
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AA seq
552 aa
AA seq
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MSPTAARILAAQPAGHSGPYQGHVTFLGAGPGDPGLLTLRAVEALARADVLVAEPRAYDV
VRAHLRPGTDTPLQNGALATTASDAADLVMRAARSGKRVVRAVAGDPGMDTDATADMLAL
AAEGITFEVVPGIAHAVGVAAYAGVPLRDPEGTDVRFVDAATADERCWTEVGASDATVVV
SAVLETVAGTAARLISSGRKPDTPVSVTIAGTTTRQRTWSATLGTVERTLKSAKVLPSPE
GDRPVIAVVGERGANARRDELAWFESKPLFGWKVLVPRTKEQAASLSEQLRSYGAVPSEV
PTIAVEPPRTPQQMDRAVKGLVTGRYEWIAFTSVNAVRAIREKFEEYGLDARAFAGIKVA
AVGEQTARALIDFGVRPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATETLV
AGLVEMGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHN
VTVIACIGPATAKTAQEHGLRVDVLAPEPSVHALAEALAQYGEQRRAAALEAGEVLKRPS
EKRPQRRRARTS
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccgccgcacgcatcctggcggcccagccggccggtcactccggtccgtac
caagggcacgtcacctttctcggggccggaccgggcgatccgggcctgctgaccctgcgc
gccgtggaggcgctcgcccgggccgatgtcctggtcgccgagccacgggcgtacgacgtg
gtgcgcgcgcatctgcggccggggacggacaccccgctgcagaacggcgctctcgccacc
acggcgagtgatgccgccgatcttgtcatgcgggccgcgcgcagcggcaagcgggtggtc
cgtgcggtcgccggtgaccccggtatggacacggacgccaccgccgacatgctggcgctg
gccgccgagggcatcaccttcgaggtggtgccgggcatcgcgcacgccgtgggcgtggcc
gcgtacgccggggtgccgctgcgtgatcccgagggcaccgatgtgcggttcgtggacgcg
gcgaccgccgacgagcggtgctggacggaggtcggcgcgagcgacgccacggtggtggtg
tcggcggtgctggagacggtggccggcacggccgcgcggctgatctcctcgggccgcaag
ccggacaccccggtgtcggtgacgatcgcgggcaccacgacccggcagcggacctggtcg
gcgacgctgggcacggtcgagcggacgctgaagtcggcgaaggtgctgccctcgccggag
ggcgaccggccggtgatagccgtcgtgggcgagcgcggggcgaacgcccggcgcgatgag
ctggcgtggttcgagtccaagccgctgttcggctggaaggtgctggtgccgcggacgaag
gagcaggcggcctcgctctcggagcagctgcggtcctacggcgcggtgcccagcgaggtg
ccgacgatcgcggtggagccgccgcgtaccccgcagcagatggaccgggcggtcaagggc
ctggtgaccgggcgctacgagtggatcgcgttcacctcggtgaacgcggtgcgggcgatc
cgggagaagttcgaggagtacggtcttgacgcgcgggcgttcgccgggatcaaggtggcg
gcggtcggtgagcagaccgcccgggcgctgatcgacttcggggtgcgcccggacctggtg
cccagcggtgagcagtcggccgccgggctgctggaggactggccgccgtacgacccggtg
ttcgacccgatcgaccgggtgttcctgccgcgggccgacatcgccaccgagacgctggtg
gcgggcctggtcgagatgggctgggaggtggacgacgtgacggcgtaccggacggtgcgc
gcctcgccgccgccggccgagacccgggaggcgatcaagggcggcgggttcgacgcggtg
ctgttcacctcctcgtccacggtgcggaacctggtcgggatcgcgggcaagccgcacaat
gtgacggtgatcgcgtgcatcggcccggcgacggcgaagaccgcgcaggagcacgggctg
cgggtggacgtactggcgcccgagccgtcggtgcacgcgctggccgaggcgctggcccag
tacggggagcagcgccgggcggcggccctggaggccggtgaggtgctgaagcggccgagc
gagaagcgtccgcagcgacggagggcccgtacgtcatga
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