Streptomyces hawaiiensis: CEB94_23355
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Entry
CEB94_23355 CDS
T06917
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
shaw
Streptomyces hawaiiensis
Pathway
shaw00860
Porphyrin metabolism
shaw01100
Metabolic pathways
shaw01110
Biosynthesis of secondary metabolites
shaw01120
Microbial metabolism in diverse environments
shaw01240
Biosynthesis of cofactors
Module
shaw_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
shaw_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
shaw00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CEB94_23355
Enzymes [BR:
shaw01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CEB94_23355
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CEB94_23355
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QCD57455
UniProt:
A0A6G5RH52
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Position
4981343..4983049
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AA seq
568 aa
AA seq
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MSPTTLSAGPEHGHVTFLGAGPGDPGLLTLRAVEALAHADVLVAEHEVLDVVRQHARQGV
SEVHTDPDPSQDPAPGTGAPQLTVVDGTSTSAAVPVVRDAAHLVMEAARGGRRVVRAVSG
DPGLDTYAAEEMLACAAAGVPFEVVPGIASAVGVPAYAGVPLRDAQGADVRFVDARTASD
RCWTEVGASDGTVVVSTTLDSVAAAAGELVSAGRKPDTPMTVTVAGTTTRQRTWTATLGT
IAQTLKQAKVLPSPDGGRPVIAVVGERSSAAQRDQLAWFESKPLFGWKVLVPRTKEQAVS
LSDQLRSYGAVPYEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFE
EYGLDARAFAGIKVAAVGEQTAKALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPID
RVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSS
STVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVLKLAEALADFGAKR
RAAAVEAGDPVTRPSERRPGARRRRSTT
NT seq
1707 nt
NT seq
+upstream
nt +downstream
nt
gtgagccccaccaccctttccgccggtcctgaacacgggcacgtcaccttcctgggtgcc
ggacccggagatccgggactgctgactctgcgcgccgtggaggcgctggcgcacgcggac
gtcctcgtcgccgagcacgaggtgctcgacgtcgtacgtcagcacgccaggcagggcgtc
tccgaagtgcacacggacccggatccttcccaggacccggcgccgggcacaggagcgccc
cagctgacggtagttgacggcacgtcaacctccgcagccgtccccgtggtgcgggatgcc
gcacatcttgtcatggaggccgcgcggggcggcaggcgggtcgtgcgtgcggtgtccggg
gacccgggcctcgacacgtacgccgccgaggagatgctggcgtgcgccgccgccggggtg
cccttcgaggtcgtccccggcatcgcgagcgccgtcggcgtgcccgcctacgccggtgtg
ccgctgcgcgacgcgcagggcgcggacgtgcggttcgtggacgcgcgcacggcgtcggac
cggtgctggacggaggtcggggcgtcggacggcacggtcgtcgtctccacgacgctggac
tccgtcgccgcggcggccggcgaactcgtctccgccgggcgcaagccggacaccccgatg
acggtcaccgtcgccggtacgaccacccggcagcgcacctggaccgccacgctcggcacg
atcgcgcagacgctgaagcaggccaaggtgctgccctcgcccgacggcggccggccggtg
atagccgtggtcggggagcgttcctccgccgcccagcgcgaccagctcgcgtggttcgag
tccaagccgctgttcggctggaaggtgctcgttccgcgtacgaaggagcaggcggtgtcg
ctctccgaccagctgcggtcgtacggggccgtgccgtacgaggtgccgaccatcgccgtc
gagccgccgcgcacgccccagcagatggagcgcgcggtcaagggcctggtgacgggccgc
tacgagtggatcgccttcacctcggtgaacgcggtcaaggccgtgcgggagaagttcgag
gagtacgggctcgacgcgcgtgccttcgcgggcatcaaggtcgcggccgtcggcgagcag
acggccaaggcgctgatcgcgttcggcgtgaagccggacctggtgccgagcggtgagcag
tcggccgccggtctgctggaggactggccgccctacgacccggtcttcgacccgatcgac
agagtgttcctgccgcgtgccgacatcgccacggagacgctggtggccgggctgatcgag
ctcggctgggaggtcgacgacgtcacggcctaccggaccgtgcgggcctcgccgccgccg
gcggagacccgcgaggcgatcaagggcggtggcttcgacgccgttctcttcacctcgtcc
tccaccgtgcgcaacctggtcggcatcgccggcaagccgcacaacgtcaccgtgatcgcc
tgtatcggcccggccacggccaagaccgccgaggagcacggactccgggtggacgtcatg
gctccggaaccgtccgtgctcaagctggcggaggccctggccgacttcggcgcgaagcgc
cgggcggcggctgtggaggccggggacccggtgacgcggccgagcgagcggcggccgggg
gctcggcgcaggcgctctacgacgtaa
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