Streptomyces incarnatus: ABB07_11260
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Entry
ABB07_11260 CDS
T09785
Name
(GenBank) isopropylmalate isomerase
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sinn
Streptomyces incarnatus
Pathway
sinn00290
Valine, leucine and isoleucine biosynthesis
sinn00660
C5-Branched dibasic acid metabolism
sinn01100
Metabolic pathways
sinn01110
Biosynthesis of secondary metabolites
sinn01210
2-Oxocarboxylic acid metabolism
sinn01230
Biosynthesis of amino acids
Module
sinn_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sinn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
ABB07_11260
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ABB07_11260
Enzymes [BR:
sinn01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
ABB07_11260
4.2.1.35 (R)-2-methylmalate dehydratase
ABB07_11260
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
AKJ10574
UniProt:
A0A0G3AI49
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Position
complement(2609038..2610462)
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRQNGRQVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVEGELPEGVTA
KDLILAIIAKIGTGGGQGYVLEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLKGRPHAPEGADWDAAVEYWKTLRTDDDAEFDAEVVIDAAELSPFVTWGTNPGQGAPL
SASVPDPASYEDASERLAAEKALEYMGLEAGQPLRSIKVDTVFVGSCTNGRIEDLRAAAE
LLKGRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDAPVPAGV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccacgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacgggctgcgccagaacggccgccaggtgcggcgcctcgacctcaccatcgccacc
gaggaccacaacacccccaccctcgacatcgacaagcccatcgccgacccggtctcccgc
gcccagctggagacgctgcgcaagaactgcgccgagttcggggtgcggctgcacccgctg
ggcgacgtcgagcagggcgtcgtgcacgtcgtcggcccccagctgggtctgacccagccc
ggtacgaccgtggtctgcggtgactcccacacctccacgcacggcgcgttcggcgcgctg
gcgttcggcatcggcacctcccaggtcgagcacgtgctggccacccagacgctgccgctg
gcccgccccaagaccatggcgatcacggtcgagggcgagctgcccgagggtgtcaccgcc
aaggacctgatcctggcgatcatcgcgaagatcggtacgggtggcggccagggctacgtc
ctggagtaccgcggctccgccatcgagaagctctcgatggaggcccggatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagaccaccttc
gcctacctcaagggccgcccgcacgcccccgagggcgccgactgggacgcggcggtcgag
tactggaagacgctgcgcaccgacgacgacgccgagttcgacgccgaggtcgtgatcgac
gccgccgagctgtcgccgttcgtcacctggggcaccaaccccggccagggcgcgccgctt
tcggcgtccgtccccgacccggcttcgtacgaagacgcttcggagcgcctcgccgccgaa
aaggccctggagtacatggggttggaggccggccagccgctgcgctccatcaaggtggac
accgtcttcgtaggctcctgcaccaacggccgcatcgaggacctgcgcgccgccgccgag
ctcctcaagggccgcaaagtcgccgacggcgtacggatgctggtcgtcccgggctccgcg
cgcgtgggtctgcaggccgtctccgagggcctggacgtggtcttcaaggaggccggcgcc
gaatggcggcacgcgggctgctcgatgtgcctcggcatgaaccccgaccagctggccccg
ggcgagcgctccgcctccacctccaaccgcaacttcgagggccggcagggcaagggcggt
cgtacgcacctggtgtcgccgcaggtcgcggccgcgaccgccgtcctgggccacctggcc
tcgcccgccgacctgtccgacgcccccgtgcccgctggagtctga
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