Streptomyces janthinus: RI060_17750
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Entry
RI060_17750 CDS
T09385
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sjn
Streptomyces janthinus
Pathway
sjn00860
Porphyrin metabolism
sjn01100
Metabolic pathways
sjn01110
Biosynthesis of secondary metabolites
sjn01120
Microbial metabolism in diverse environments
sjn01240
Biosynthesis of cofactors
Module
sjn_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sjn_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sjn00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
RI060_17750
Enzymes [BR:
sjn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
RI060_17750
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
RI060_17750
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Gene cluster
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
WND19078
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Position
complement(3901380..3903086)
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AA seq
568 aa
AA seq
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MSPTTLSAGPEHGHVTFLGAGPGDPGLLTLRAVEALASADVLVAEHEVLDVVRQHARQGV
SEVHTDSDPSQDPAPGTGTPQLTVVDGTSTTAAVPAVRDAAHLVMEAARGGRRVVRAVSG
DPGLDTYAAEEMLACAAAGVPFEVVPGIASAVGVPAYAGVPLRDAQGADVRFVDARTASD
RCWTEVGASDGTVVVSTTLDSVAAAAGELVSAGRKPDTPMTVTVAGTTTRQRTWTATLGT
IAQTLKQAKVLPSPEGGRPVIAVVGERSAAAQRDQLAWFESKPMFGWKVLVPRTKEQAAS
LSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFE
EYGLDARAFAGIKVAAVGEQTAQALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPID
RVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSS
STVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALADFGAKR
RAAAVEAGDAVTRPSERRPGARRRRSTT
NT seq
1707 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccaccctttccgccggtcctgaacacgggcacgtcaccttcctgggtgcc
ggacccggagatccgggactgcttactctgcgcgccgtagaggcgctggcgagcgcggac
gttctcgtcgccgagcacgaggtgctcgacgtcgtacgtcagcacgccaggcagggcgtc
tccgaagtgcacacggattcggatccttcccaggatccggcgccgggcacaggaacgccc
cagctgacggtagttgacggcacgtcaaccaccgccgctgtccccgcggtgcgggatgcc
gcacatcttgtcatggaggccgcgcggggcggcaggcgggtcgtgcgtgcggtgtccggt
gacccgggcctcgacacgtacgccgccgaggagatgctggcgtgcgccgccgccggggtg
cctttcgaggtggtgcccggtatcgcgagcgccgtcggtgtgcccgcgtacgccggtgtg
ccgctgcgggacgcgcagggcgcggacgtgcggttcgtggacgcgcggacggcgtcggac
cggtgctggacggaggtcggggcgtcggacggcacggtggtcgtgtccaccacgctggac
tccgtcgccgcggcggccggtgagctggtctccgcgggccgcaagccggacaccccgatg
acggtcaccgtcgccggtacgaccacccggcagcgcacctggaccgccacgctcggcacg
atcgcgcagacgctgaagcaggccaaggtgctgccctcgccggagggcggccggccggtg
atagccgtggtcggtgagcgttccgccgccgcccagcgcgaccagctcgcgtggttcgag
tccaagccgatgttcggctggaaggtactcgtgccgcgcacgaaggagcaggcggcgtcg
ctctccgaccagctgcggtcgtacggtgccgtgccgcacgaggtgccgaccatcgccgtc
gagccgccgcgcacgccccagcagatggagcgggcggtcaaggggctcgtgacgggccgc
tacgagtggatcgccttcacctcggtgaacgcggtcaaggccgtgcgggagaagttcgag
gagtacgggctcgatgcccgggccttcgcggggatcaaggtcgctgcggtcggtgagcag
acggcccaggcgctgatcgcgttcggtgtgaagccggacctggtgccgagcggggagcag
agcgctgccggtctgctggaggactggccgccgtacgacccggtcttcgacccgatcgac
cgggtgttcctgccgcgcgccgacatcgccacggagacgctggtcgccgggctgatcgag
ctgggctgggaggtcgacgacgtcacggcctaccggaccgtgcgggcctcgccgccgccg
gcggagacgcgcgaggcgatcaagggcggtgggttcgacgccgtgctgttcacgtcgtcg
tcgaccgtgcggaacctggtcggtatcgccggcaagccgcacaacgtgaccgtgatcgcg
tgtatcggcccggccacggcgaagaccgccgaggagcacgggctccgggtggacgtcatg
gcgcccgagccgtccgtgcacaagctggccgaggcgctggccgacttcggcgcgaagcgg
agagctgccgctgttgaggccggggatgcggtcacccggccgagcgagcggcggccgggg
gcgcggcggcggcgttcgacgacgtga
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