Streptomyces laurentii: SLA_5454
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Entry
SLA_5454 CDS
T05205
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
slau
Streptomyces laurentii
Pathway
slau00290
Valine, leucine and isoleucine biosynthesis
slau00660
C5-Branched dibasic acid metabolism
slau01100
Metabolic pathways
slau01110
Biosynthesis of secondary metabolites
slau01210
2-Oxocarboxylic acid metabolism
slau01230
Biosynthesis of amino acids
Module
slau_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
slau00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
SLA_5454
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SLA_5454
Enzymes [BR:
slau01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
SLA_5454
4.2.1.35 (R)-2-methylmalate dehydratase
SLA_5454
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
BAU86327
UniProt:
A0A160P3W5
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Position
5688377..5689801
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRLGGRQVRRLDLTLAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHPLGDIEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPRTMAITVDGELPADVTA
KDLILAVIAKIGTGGGQGYVLEYRGSAIEKLSMESRMTICNMSIEAGARAGMIAPDETTF
AYLKGRAHAPEGEDWDAAVAYWKTLRTDEDAVFDAEVVIDAAELAPFVTWGTNPGQGAPL
SAHVPDPASYEDASERLAAEKALEYMGLTAGQPLRAIEVDTVFVGSCTNGRIEDLRNAAE
LLKGRKVADGVRMLVVPGSVRVALQAVEEGLDRVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDVVTPAGV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgccgaaggc
gagcccgatctcctcttcatcgatcttcacctgctgcacgaggtgaccagcccccaggcg
ttcgacgggctgcggctcggcggccggcaggtgcgcaggctcgacctgaccctggccacc
gaggaccacaacacccccaccctcgacatcgacaagccgatcgccgacccggtctcccgc
gcccagttggagaccctgcgcaagaactgcgccgagttcggcgtccggctgcacccgctc
ggcgacatcgagcagggcgtcgtccacgtggtgggaccgcagctggggctgacccagccg
ggcaccacggtggtctgcggcgactcgcacacctccacccacggcgccttcggcgcgctg
gcgttcggcatcggcaccagccaggtcgagcacgtcctcgccacccagacgctgccgctg
gcccggccccggaccatggccatcacggtcgacggcgaactgccggcggacgtcaccgcc
aaggacctgatcctggcggtcatcgcgaagatcggcaccggcggcggccaggggtacgtc
ctggaataccgcggctccgccatcgagaaactctcgatggagtcccggatgaccatctgc
aacatgtccatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagaccaccttc
gcctacctcaagggccgcgcccacgctcccgagggcgaggactgggacgccgccgtcgcg
tactggaagaccctgcgcaccgacgaggacgcggtcttcgacgccgaggtcgtcatcgac
gccgccgagctggcaccgttcgtcacctggggcaccaaccccggccagggcgccccgctt
tcggcgcacgtccccgacccggcttcgtacgaagacgcatcggagcgcctcgccgccgaa
aaggccctggaatacatggggttgaccgccgggcagccgctgcgcgccatcgaggtcgac
accgtcttcgtaggctcctgcaccaacggccgcatcgaggacctgcgcaacgccgccgag
ctcctcaagggccgcaaggtcgccgacggcgtccgcatgctggtggtccccggctccgtc
cgggtcgccctgcaggccgtcgaggagggcctggaccgggtcttcaaggaggccggcgcc
gaatggcggcacgcgggctgctcgatgtgcctgggcatgaaccccgaccaactggccccc
ggcgagcgctccgcgtccacctccaaccgcaacttcgagggccggcagggcaagggcggc
cgcacccacctggtctccccccaggtcgccgccgccaccgccgtcctcggtcacctggcc
tccccggccgacctgtccgacgtcgtcactcccgcgggggtctga
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