Streptomyces lunaelactis: SLUN_28180
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Entry
SLUN_28180 CDS
T06347
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
slk
Streptomyces lunaelactis
Pathway
slk00290
Valine, leucine and isoleucine biosynthesis
slk00660
C5-Branched dibasic acid metabolism
slk01100
Metabolic pathways
slk01110
Biosynthesis of secondary metabolites
slk01210
2-Oxocarboxylic acid metabolism
slk01230
Biosynthesis of amino acids
Module
slk_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
slk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
SLUN_28180 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SLUN_28180 (leuC)
Enzymes [BR:
slk01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
SLUN_28180 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
SLUN_28180 (leuC)
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Motif
Pfam:
Aconitase
AcnX
DUF4946
Motif
Other DBs
NCBI-ProteinID:
AVZ75508
UniProt:
A0A2R4T8Q5
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Position
6097196..6098620
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLYIDLHLLHEVTSPQAFDGLRQNGRQVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRIQLETLRKNCADFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVEGELPETVTA
KDLILAIIARIGTGGGQGYILEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDRTTF
DYLQGRDHAPEGADWDAAVEYWQTLRTDDDAVFDAEVFIDATELAPFVTWGTNPGQGAPL
SANVPDPASYEDASERHAAEKALEYMGLSAGQPLRDIKVDTVFVGSCTNGRIEDLRNVAS
ILDGRKVADGVRMLVVPGSVRVALQAVSEGLDKVFTAAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDAPATAGV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccacgtcgtccggcgcgcagagggc
gagcccgacctcctctacatcgatctgcatctgctgcacgaggtgaccagcccccaggct
ttcgacgggctccggcagaacggccgccaggtccgccgcctcgacctcaccatcgctacc
gaggaccacaacaccccgacgctggacatcgacaagcccatcgcggacccggtctcccgc
atccagttggagacgctccgcaagaactgtgccgacttcggcgtccgtctgcacccgctg
ggcgacgtcgagcagggcgtcgtccacgtcgtgggcccgcagctgggcctgacccagccc
ggcaccaccgtggtctgcggcgactcccacacctccacgcacggcgccttcggcgccctc
gcgttcggcatcggcacctcccaggtggagcatgtgctggccacccagacgctgccgctg
gcccgccccaagaccatggccatcacggtcgagggcgaactgcccgagaccgtcaccgcc
aaggacctgatcctggccatcatcgccaggatcggcaccggcggcggccagggctacatc
ctggaataccgcggctccgccatcgagaagctctcgatggaggcccggatgaccatctgc
aacatgtcgatcgaggcgggcgcccgggccggaatgatcgccccggaccgcaccaccttc
gactatctgcagggccgcgaccacgcccccgagggcgcggactgggacgcggccgtcgag
tactggcagaccctgcgcaccgacgacgacgccgtattcgacgccgaggtgttcatcgac
gccaccgaactggcgccgttcgtcacctggggcaccaaccccggccagggcgcgcccctg
tcggcgaacgtccccgaccctgcttcgtacgaggacgcttcggagcgccacgccgccgaa
aaggccctggagtacatggggttgagcgccggccagccgctgcgcgacatcaaggtcgac
accgtcttcgtaggctcctgcaccaacggccgtatcgaggacctgcgcaacgttgcctcg
atcctggacggccgcaaagtcgccgacggcgtacggatgctggtggtccccggctccgta
cgagtcgccctgcaggccgtctcggagggcctggacaaggtcttcaccgccgcgggcgcc
gaatggcggcacgcgggctgctcgatgtgtctgggcatgaaccccgaccaactggcccct
ggcgagcgctccgcgtcgacctccaaccgcaacttcgagggcaggcagggcaagggcgga
cgcacccatctggtctcgccccaggtcgccgcggccaccgcggtactgggccatctggcc
tcgcccgccgatctgtccgacgcccccgcgaccgccggagtctga
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