Streptomyces malaysiensis: SMALA_3638
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Entry
SMALA_3638 CDS
T05189
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
smal
Streptomyces malaysiensis
Pathway
smal00290
Valine, leucine and isoleucine biosynthesis
smal00660
C5-Branched dibasic acid metabolism
smal01100
Metabolic pathways
smal01110
Biosynthesis of secondary metabolites
smal01210
2-Oxocarboxylic acid metabolism
smal01230
Biosynthesis of amino acids
Module
smal_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
smal00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
SMALA_3638
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SMALA_3638
Enzymes [BR:
smal01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
SMALA_3638
4.2.1.35 (R)-2-methylmalate dehydratase
SMALA_3638
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GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
ATL83872
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Position
4653432..4654682
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AA seq
416 aa
AA seq
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MNLVEKILARASGKPSVEPGEIVIAEVDMLLMHDLSGYLTSGVYDKQVGLPIPHPERTLM
VFDHHYSPPTEQQADVLHHNREWARRTGINLLDCGNGNLHHAAVRGGFVKPGMIVVGSDS
HTPVHGALGALAVALGNDSHAGTVLPYGKAWFRVPETVRIELTGEPRPGTTPRDIALWLT
AEIGEGAMNYKALEFTGPYVKQLGFWDRWLFPLLCVDLGAKSSYVEPDEVTEAFVRTLPG
GLPYDLPRGDGGEAATVLRYDVSDVVPQVACPPTVGNAKAVSDVAGRQVRYAELGGHGGG
RIEDIRTAAEVLHGRTVHPDTRFNIVPSSREVFAQAVREGLVLALHEAGATWFPPSTGSN
QAINMGAMAAGEAMISTHARNFPGRNGSTRAEMYLASARTVAASAVAGEIAERSTR
NT seq
1251 nt
NT seq
+upstream
nt +downstream
nt
gtgaacctggtcgagaagatcctcgcacgggcgagcggcaaaccgtccgtggagcccggc
gagatcgtcatcgccgaggtggacatgctgctgatgcacgacctcagcggctatctcacc
tccggcgtctacgacaagcaggtcggtctgccgatcccgcatcccgagcgcaccctgatg
gtcttcgaccaccactactcgccgcccaccgagcagcaggccgatgtgctccaccacaac
cgcgagtgggcccgccgcaccggtatcaacctcctggactgcggcaacggcaacctccac
cacgccgcggtgcgcggcggcttcgtcaagcccggcatgatcgtcgtcggctccgacagc
cacacgcccgtgcacggcgcgctcggcgccctcgccgtggcgctcggcaacgactcgcac
gccggcacggtgctcccgtacggcaaggcgtggttccgggtgcccgagaccgtgcggatc
gagctgacgggggagccacggcccggcacgacgccccgggacatcgccctgtggctgacc
gcggagatcggcgagggcgcgatgaactacaaggcgctggagttcaccgggccctacgtc
aagcagctgggcttctgggaccgctggctgttcccgctgctctgcgtggacctgggcgcc
aagagcagctacgtggagcccgacgaggtcaccgaggcgttcgtgcgcaccctgccgggc
ggcctgccgtacgacctgccgcgcggtgacggcggcgaggccgcgaccgtgctgcggtac
gacgtgagcgatgtggtgccccaggtcgcctgcccgccgacggtcggcaacgccaaggcc
gtctcggacgtggccggccgccaggtgcggtacgcggagctcggcggccacggcggcggc
cggatcgaggacatcaggacggccgctgaggtgctgcacggccgcaccgtccacccggac
acccgtttcaacatcgtgccgtcgagccgcgaggtgttcgcgcaggccgtgcgggagggt
ctggtgctcgcgctgcacgaggccggagccacgtggttcccgccgagcaccggctccaac
caggccatcaacatgggcgcgatggcggcgggcgaagccatgatctccacccatgcccgc
aacttccccgggcgcaacggcagcacccgggccgagatgtacctggcgtccgcgcggacc
gtggcggcgtcggccgtggcgggcgagatcgccgagaggagcacccggtga
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