Streptococcus mutans NN2025 (serotype c): SmuNN2025_0026
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Entry
SmuNN2025_0026 CDS
T01185
Symbol
purL
Name
(GenBank) putative phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
smc
Streptococcus mutans NN2025 (serotype c)
Pathway
smc00230
Purine metabolism
smc01100
Metabolic pathways
smc01110
Biosynthesis of secondary metabolites
Module
smc_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
smc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
SmuNN2025_0026 (purL)
Enzymes [BR:
smc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
SmuNN2025_0026 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
GATase_3
DJ-1_PfpI
Motif
Other DBs
NCBI-ProteinID:
BAH87052
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Position
32475..36200
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AA seq
1241 aa
AA seq
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MDRRIFVEKKANFSIKSESLVKELTHNLQLTSLKILRIVQVYDIFNLEESLFARAQKHVF
SEQVTDTILDEATVQADLNNHAFFAIEALPGQFDQRAASSQEALLLLGSDSNVTVNTAQL
YLVNKDIDASELEAVKHYLLNPVDSRFKDITLPIRPQEFSNSDKTIPNLDFFKTYTAEDF
AAYKAEQGLAMEVDDLVFIQDYFKSIGRVPTETELKVLDTYWSDHCRHTTFETELKNINF
SASKFQKQLQATYDKYIAMRDELGRSEKPQTLMDMATIFGRYERANGRLNDMEVSDEINA
CSVEIEVDVDGIKEPWLLMFKNETHNHPTEIEPFGGAATCIGGAIRDPLSGRSYVYQAMR
ISGAGDITASIAETRSGKLPQQVISKTAAHGYSSYGNQIGLATTYVKEYFHPGFVAKRME
LGAVVGAAPKENVVREKPEPGDVVILLGGKTGRDGVGGATGSSKVQTVESVETAGAEVQK
GNAIEERKIQRLFRNGNVTRLIKKSNDFGAGGVCVAIGELADGLEIDLDKVPLKYQGLNG
TEIAISESQERMSVVVRPSDVDAFIAACHKENIDAVVVATVTEKPNLVMTWKGETIVDLE
RAFLDTNGVRVVVDANVVDKDVALPEVRTTSAATLEADTVKVLSDLNHASQKGLQTIFDS
SVGRSTVNHPIGGRYQITPTESSVQKLPVQNGVTTTASVMAQGFNPYIAEWSPYHGAAYA
VIEATARLVATGADWSRARFSYQEYFERMDKQADRFGQPVAALLGSIEAQIQLGLPSIGG
KDSMSGTFEELTVPPTLVAFGVTTVDSRQVLSPEFKTVGENIYYISGQAISEDIDFDYIK
ANFAQFEAVQAKHKVTAASAIKYGGVLESLALMSFGNHIGASVELTELDSNLTAQLGGFV
FTSDEAIADAVKIGQTVADFTVTVNGVNLSAAKLLAAFEGKLEDVYPTEFEQSTALEEVP
AVVSDAVIKAKERIAQPLVYIPVFPGSNSEYDSAKAFEQAGAKVNSVPFVTLNEAAIEAS
VDTMVDNIAKANIIFFVGGFSAADEPDGSAKFIINILLNEKVRSAIDSFIERGGLIIGIC
NGFQALVKSGLLPYGDFEEVGETSPTLFYNDANQHVAKMVETRITNTNSPWLAGVKIGDI
HVIPVSHGEGKFVVTAEEFAELCDNGQIWSQYVDFDGKPSMDSKYNPNGSLNAIEGITSK
NGQIIGKMGHSERYENGLFQNIPGNKDQGLFESAVKYFTGK
NT seq
3726 nt
NT seq
+upstream
nt +downstream
nt
atggatagacgtatttttgttgagaaaaaagctaactttagcattaaatcggagtcactg
gtcaaagaactaacacataatttgcagttaacctccttaaaaattttacgtattgtgcag
gtttatgatatctttaatttagaagaaagcctgtttgcgcgtgcgcaaaagcatgtcttt
tctgagcaggtgacagatacaattttagatgaagcaactgtgcaggcggatcttaacaac
catgctttttttgctattgaagctttgccgggtcagtttgaccagcgggcagcaagttca
caagaagctttgctcttacttggtagtgacagcaacgtaacggttaatactgcccagctt
tatctggttaataaggatattgatgcatctgagttggaagcggtgaagcattatcttttg
aatccagttgattcgcgtttcaaagatatcaccttgcctattcgtccacaggaattttca
aattctgacaaaacaattccaaatttggatttctttaagacttatacagctgaagatttt
gcggcttacaaggcggaacaaggtttggctatggaagtggatgatcttgtttttattcaa
gattattttaaatcaattgggcgtgtgccaacagaaacggaattgaaagttttggatacc
tactggtctgaccactgccgtcacacgacttttgagacagaattgaaaaatattaacttt
tcagcttctaagttccaaaaacaattgcaggcaacttatgataaatatattgccatgcgt
gacgaattgggacgttctgaaaagccacagacgcttatggatatggcgacaatctttggt
cgttatgagcgtgctaacggtcgtttgaacgacatggaagtgtcggacgaaatcaatgcc
tgctcggttgaaattgaggtagatgtagatggcatcaaagaaccttggctgctcatgttc
aaaaatgaaacccacaatcacccaacggaaattgagcctttcggtggagctgcaacttgt
attggtggtgctattcgtgacccattgtcaggtcgttcttatgtttaccaagctatgcgt
atatcaggtgcaggtgatattaccgcatcaatagcagaaacacgctctggtaaattgcca
caacaagtcatctctaaaacggcggcgcacggctattcgtcatacgggaaccaaatagga
cttgcgactacctatgtcaaagagtacttccatccaggcttcgttgctaagcgtatggag
ctaggtgctgttgtcggtgcagcaccaaaagaaaatgtcgtgcgtgaaaaaccagaacct
ggtgatgtggtcatccttcttggtggaaaaacaggacgtgacggtgtcggtggtgctaca
ggctcatctaaggttcaaacggttgaatcggttgagacagcaggtgccgaagtgcaaaaa
gggaatgctattgaagaacgtaagattcaacgtcttttccgcaatggcaatgtcactcgt
ctcatcaagaaatcaaatgactttggtgctggcggcgtctgtgtggctattggtgaattg
gcagatggtcttgaaattgacttggacaaagtgccactaaaataccaaggtcttaacggt
accgaaattgccatttctgagtcacaagaacgcatgtctgttgttgttcgtccaagtgat
gtggacgcctttattgcagcatgtcataaagagaacattgatgcagttgttgtcgcgact
gttactgaaaaaccaaaccttgtcatgacttggaagggtgaaaccatcgttgacttggaa
cgtgctttccttgatactaacggtgtgcgtgtggttgttgatgcaaacgttgtggataag
gatgttgcccttcctgaggtgcgtacaacatcagcagcaacacttgaagcagacacagtg
aaagttctgtctgatcttaaccacgctagtcaaaaagggttgcaaactatctttgacagc
tcggttgggcgttcaacagttaatcatccaatcggcggtcgttatcaaattacgcctact
gaaagctctgtgcaaaaattgccagtacaaaatggtgtcacaacgacagcttctgtcatg
gcacagggattcaatccttatattgcggagtggtcaccttatcatggtgcagcttacgct
gttattgaagcaacagctcgcttggtagcaacaggtgctgattggtctcgtgcgcgtttc
tcttaccaagaatactttgaacgcatggataaacaagcggatcgctttggtcagccagta
gctgctctgcttggttcgatcgaggcacaaatccaacttggtttgccatcaatcggtggt
aaggactccatgtcaggtacctttgaagaattgacggtaccgccaaccttggttgccttt
ggtgtgacaacagtagatagtcgtcaggttctttcaccagaattcaagactgttggtgag
aacatttactacatctcaggacaggctatttcagaagacattgattttgattatatcaag
gctaactttgcacaatttgaagccgttcaagctaagcataaagtaacagcagcttcagct
attaaatacggcggtgttcttgaaagcctagcactcatgagctttggtaatcatattggt
gcttctgtagaattgacagagcttgacagcaacttgacagcgcagcttggtggttttgtc
tttacatctgatgaagccattgctgacgcagtgaaaattggtcaaactgtggcagacttt
acagtaactgtcaacggtgtcaacttgtccgctgcgaaattgcttgcagcctttgaaggc
aagttggaagatgtttatccaactgagtttgaacagtcaacagctcttgaagaagtacct
gctgtggtatctgatgctgttattaaagctaaagaaagaattgcacagcctctggtttat
atcccagttttccctggttccaattcagaatatgattcagctaaggcctttgaacaagct
ggtgccaaagtcaactcagtgccatttgtgactcttaatgaagcagcaattgaggcttct
gttgacaccatggttgacaacattgctaaagccaatattatcttctttgtcggcggcttc
tcagcggcagatgagccagatggttcggctaagtttatcatcaatatcttacttaatgaa
aaagttcgctctgctattgacagcttcattgaaaggggtggtctcatcattggtatctgt
aatgggtttcaagctcttgtcaaatccgggcttctgccttatggtgactttgaagaagtt
ggtgagacaagccccaccctcttctacaatgatgccaaccagcacgtggctaagatggtg
gaaacccgtatcactaataccaactctccatggttggcaggtgttaagatcggtgatatc
catgtaattccagtctctcacggtgaagggaaatttgtcgtgacagctgaagaatttgcg
gaactgtgtgacaatggtcaaatctggagccaatacgtggactttgatggtaagccttct
atggattctaaatacaatccaaacggttcgctcaacgctatcgaagggattacgagcaag
aacggtcaaatcattggtaagatgggacactcggaacgctatgaaaacgggctctttcaa
aacatcccaggtaacaaagaccaaggcctatttgaaagtgcagtgaaatactttactggg
aaatag
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