Sinorhizobium meliloti 1021: SMc03112
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Entry
SMc03112 CDS
T00058
Symbol
metH
Name
(GenBank) Probable 5-methyltetrahydrofolate--homocysteine methyltransferase (methionine synthase, vitamin-B12 dependent isozyme) protein
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
sme
Sinorhizobium meliloti 1021
Pathway
sme00270
Cysteine and methionine metabolism
sme00450
Selenocompound metabolism
sme00670
One carbon pool by folate
sme01100
Metabolic pathways
sme01110
Biosynthesis of secondary metabolites
sme01230
Biosynthesis of amino acids
sme04980
Cobalamin transport and metabolism
Module
sme_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
sme00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SMc03112 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
SMc03112 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SMc03112 (metH)
09150 Organismal Systems
09154 Digestive system
04980 Cobalamin transport and metabolism
SMc03112 (metH)
Enzymes [BR:
sme01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
SMc03112 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
DUF1129
Motif
Other DBs
NCBI-ProteinID:
CAC47560
RhizoBase:
SMc03112
UniProt:
Q92LQ0
LinkDB
All DBs
Position
complement(3225354..3229127)
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AA seq
1257 aa
AA seq
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MSAADALFGNVSPKPDGSEVFRQLAQAAAERILIMDGAMGTEIQQLGFVEDHFRGERFGG
CACHQQGNNDLLTLTQPKAIEDIHYHYAIAGADILETNTFSSTRIAQADYGMEDMVYDLN
RDGARLARRAAKRAEAEDGRRRFVAGALGPTNRTASISPDVNNPGYRAVSFDDLRLAYAE
QVRGLIDGGADIILIETIFDTLNAKAAIFATQEVFAEKGVRLPVMISGTITDLSGRTLSG
QTPTAFWYSVRHADPFTIGLNCALGANAMRAHIDELSAVADTLVCAYPNAGLPNEFGRYD
ESPEQMAAQVEGFARDGLVNIVGGCCGSTPAHIRAIAEAVAKYPPRRVPEIDRRMRLSGL
EPFTLTDEIPFVNVGERTNVTGSAKFRKLITAGDYAAALDVARDQVANGAQIIDVNMDEG
LIDSKQVMVEFLNLVASEPDIARVPVMIDSSKWEVIEAGLKCVQGKALVNSISLKEGEAA
FLHHARLVRAYGAAVVVMAFDEKGQADTKTRKVEICRRAYRLLTEEVGFPPEDIIFDPNI
FAVATGIEEHNNYGVDFIEATHEIIAALPHVHVSGGVSNLSFSFRGNEPVREAMHAIFLY
HAIQAGMDMGIVNAGQLAVYDAIDPELRETCEDVVLNRRADSTERLLEIAERYRGKGGSQ
GKEKDLAWREWPVEKRLEHALVNGITEFIEADTEEARLAAERPLHVIEGPLMAGMNVVGD
LFGSGKMFLPQVVKSARVMKQAVAVLLPHMEEEKRANGGGEARESAGKILMATVKGDVHD
IGKNIVGVVLACNNYEIIDLGVMVPSAKILEVAREQKVDIVGLSGLITPSLDEMAHVASE
LEREGFDVPLLIGGATTSRVHTAVKINPRYSLGQTVYVTDASRAVGVVSSLLSPEVRDSY
KKTVRAEYLKVADAHARNEAEKRRLPLSQARANAFRIDWDAHQPKVPSFLGTRVFEGWDL
AELARYIDWTPFFQTWELKGVFPKILDDERQGAAARQLFEDAQAMVEKIVAEAWFAPKAV
IGFWPAASMGDDVRLFADEVREAELATFFTLRQQMVKRDGRPNVALADFVAPAASGKRDY
VGGFVVTAGIEEVAIAERFERANDDYSSIMVKALADRFAEAFAERMHEYVRKELWGYAPD
EAFTPQELIAEPYAGIRPAPGYPAQPDHTEKETLFRLLDAEAAIGVRLTESYAMWPGSSV
SGLYVGHPDSYYFGVAKIERDQVEDYADRKRMSVREVERWLSPILNYVPMPETEAAE
NT seq
3774 nt
NT seq
+upstream
nt +downstream
nt
atgtccgccgccgacgccctctttggaaacgtctcgcccaagccggatggttcggaagtc
tttcggcagctcgcccaggcggcggctgaacgcatcctcatcatggatggcgccatggga
acggagatccagcagctcggtttcgtggaggatcacttccgcggcgagcgcttcggtggc
tgcgcctgccatcagcagggcaacaacgacctcctgacgctcactcagccgaaggcgatc
gaggatattcattaccactacgccatcgccggcgccgatatcctcgaaaccaacaccttc
tcctcgacgcggatcgcccaggccgattacggcatggaggacatggtctacgatctcaat
cgcgacggcgcgcggctggcgcggcgagccgcgaagcgggccgaggcggaggatggccgg
cggcgcttcgtggcaggcgcgctcggccccaccaaccgcaccgcttcgatttcgccggac
gtcaacaaccccggctatcgagccgtcagcttcgacgatctgaggctcgcctatgccgag
caggtgcggggcctcatcgacggcggtgccgacatcatcctgatcgagacgatcttcgac
acgctgaatgccaaggcggcgatcttcgcgacgcaggaagtctttgccgaaaagggcgtc
cgccttccggtgatgatctccggaacgatcaccgatctctccggccgtaccctctccggc
cagacgcctacggccttctggtattcggtgcgccatgcggatccgtttacgatcgggctc
aactgcgcgctcggcgcaaatgcgatgcgcgcccatatagacgagctttcggcggtcgcc
gacacgctcgtctgcgcctatccgaatgccggcctgccgaacgagttcggccgctatgac
gaaagccccgagcagatggcggcgcaggtcgagggcttcgcccgggacggtctcgtcaac
atcgtcggcggctgctgcggttccacgccggcccatatccgcgccattgccgaagcggtt
gccaaatatccgccgcgccgggtgcccgagatcgatcgccgcatgcggctttccggcctc
gaacccttcacgcttaccgacgagattcccttcgtcaacgtcggcgaacgcaccaacgtc
accggctcggcgaagttccgcaagctgatcaccgccggggactacgccgccgcactcgat
gtggcgcgtgatcaggtggcgaatggcgcccagatcatcgacgtcaacatggacgaaggc
ctgatcgattcgaagcaggtgatggtcgagttcctgaacctcgtcgcctccgagccggat
atcgcccgtgtaccggtgatgatcgattcgtcgaaatgggaggtgatcgaagccgggctc
aaatgcgtccagggcaaggcgctggtgaactccatctcgctcaaggaaggcgaggcggct
ttcctgcaccatgcgcgcctcgtgcgcgcctatggcgccgcggtcgtggtgatggcgttc
gacgagaagggccaggccgacacgaaaacccgcaaggtggaaatctgccggcgggcctat
cggctgctgacggaagaggttggcttccccccggaggacatcatcttcgacccgaatatc
ttcgcggtcgcgaccggcatcgaggagcacaacaattacggcgtcgacttcatcgaggcg
acgcacgagatcatcgcggcactgccgcatgtccacgtctccggcggcgtgtcgaacctc
tccttttccttccgcggcaacgagccggtgcgcgaggcgatgcacgccatcttcctttat
cacgcgatccaggccggcatggacatgggcatcgtcaatgccggacagctcgccgtctat
gatgcgatcgacccggaactgcgcgaaacctgcgaggacgtggtgctcaaccgccgggcc
gattcgaccgagcgcctcctggagatcgccgagcgctatcgcgggaagggcgggagccag
ggcaaggagaaggaccttgcctggcgcgaatggccggtggagaagcggctcgaacacgcg
ctcgtcaatggaattaccgaatttatcgaagccgatacggaagaggcccggcttgccgcc
gagcggccgctgcatgtcatcgaaggcccgctgatggccgggatgaacgtcgtgggcgat
ctcttcggttccggcaagatgttcctgccgcaggtggtcaagtccgcccgggtgatgaag
caggccgttgcggtgctgctcccccatatggaggaggagaagcgcgccaatggcggcggc
gaggcgcgcgagagtgccggcaagatcctgatggcgaccgtcaagggcgacgtgcacgac
atcggcaagaacatcgtcggcgtcgtgctcgcctgcaacaattacgagatcatcgacctc
ggcgtcatggtgccctcggctaagatcctcgaagtggcgcgcgaacagaaggtcgacatc
gtcggtctttccggcctcatcacgccgtcgctggacgagatggcgcatgtcgcttccgag
ctcgaacgggagggcttcgatgtcccgctgctgatcggcggggcgacgaccagccgcgtg
cacacggccgtgaagatcaatccgcgttacagcctcggccagacggtctatgtcaccgac
gccagccgcgcggtcggcgtcgtatcgagcctgctctcgccggaagtccgcgactcctac
aagaaaacggtccgcgcggagtatctgaaggttgccgacgcacatgcccgcaacgaagcc
gagaagcgccgtctgccgctttcccaggcgcgggcgaatgcctttcggatagattgggac
gcccaccagccgaaggttccgtccttcctcggcacgcgtgttttcgagggatgggacctc
gccgaactcgcccgctatatcgactggacgccgttcttccagacctgggagctgaagggg
gtattcccgaaaatcctcgatgacgaacgccagggggctgccgctcgccagctcttcgag
gatgcgcaggcgatggtcgaaaagatcgtggccgaggcatggttcgccccgaaggccgtg
atcggcttctggccggccgccagcatgggcgacgacgtccgcctgtttgccgacgaggtg
cgcgaagccgagcttgccaccttcttcacgctccgccagcagatggtgaagcgcgacggc
cggccgaacgtcgcccttgccgacttcgtcgccccggcggcgagcggcaagcgggactat
gtcggcggtttcgtggtgacggccggcatcgaggaagtggcgatcgccgaacgcttcgaa
cgggcgaacgacgattattcctcgatcatggtcaaggcgcttgcggaccgcttcgcagag
gcctttgccgagcgcatgcatgaatatgtccgcaaggagctctggggctatgctccggac
gaagccttcacgccgcaggaattgatcgccgagccctatgccggcatccgccctgcgccc
ggctacccggcgcagcccgaccacacggaaaaggagacgcttttccggctcctggatgcg
gaagccgctatcggcgtccggctcaccgagagctatgcgatgtggccgggctcttcggta
tcgggcctctatgtcggccaccccgattcctattacttcggcgtcgcaaagatcgagcgc
gatcaggtggaggactatgccgatcgcaagcgcatgagcgtccgcgaggtcgagcgctgg
ctttcgccgatcctcaattacgtgccgatgccggagacggaagcggcggagtag
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