Streptomyces nodosus: CP978_23920
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Entry
CP978_23920 CDS
T06839
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
snq
Streptomyces nodosus
Pathway
snq00290
Valine, leucine and isoleucine biosynthesis
snq00660
C5-Branched dibasic acid metabolism
snq01100
Metabolic pathways
snq01110
Biosynthesis of secondary metabolites
snq01210
2-Oxocarboxylic acid metabolism
snq01230
Biosynthesis of amino acids
Module
snq_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
snq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
CP978_23920 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CP978_23920 (leuC)
Enzymes [BR:
snq01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
CP978_23920 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
CP978_23920 (leuC)
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Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
QEV41192
UniProt:
A0A0B5DN45
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All DBs
Position
5299765..5301189
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLYIDLHLLHEVTSPQAFDGLRKSGRRVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPMARPRTMAITIDGELPEGVTA
KDLILAIIARIGTGGGQGYVLEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLKGRPHAPEGADWDAAVEYWKTLRTDDDAAFDAEVVIDAAELSPFVTWGTNPGQGAPL
SASVPDPASYEDASERLSAEKALEYMGLAAGQPLNSITVDTVFVGSCTNGRIEDLRAAAG
ILKDRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDAPAPAGV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggaaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgccgagggc
gagcccgacctcctctacatcgatctgcatctgctgcacgaggtgaccagcccccaggcc
ttcgacgggctgcgcaagagcggccgccgggtgcgccggctcgacctgaccatcgccacc
gaggaccacaacaccccgaccctcgacatcgacaagcccatcgcggacccggtctcccgt
gcccagctggagacgctgcgcaagaactgcgccgagttcggtgtccggctgcacccgctg
ggtgacgtcgagcagggcgtcgtgcatgtcgtgggaccgcagctgggcctgacccagccg
ggcaccacggtcgtctgcggtgactcccacacctcgacgcacggtgccttcggcgctctg
gcgttcggcatcggcacctcgcaggtcgagcatgtgctggccacccagacgctgccgatg
gcccgccccaggaccatggcgatcacgatcgacggcgaactgcccgagggcgtcaccgcc
aaggacctgatcctggcgatcatcgccaggatcggcaccggcggcggccagggctatgtc
ctggagtaccgcggctcggccatcgagaagctctcgatggaggcccggatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgctccggacgagaccaccttc
gcgtatctcaagggccgcccgcacgccccggagggcgccgactgggacgccgcggtggag
tactggaagaccctgcgcaccgacgacgacgccgcattcgacgccgaggtcgtcatcgac
gccgccgagctctcgccgttcgtcacctggggcaccaacccgggccagggcgcgccgctt
tcggcctccgtgcccgatcccgcctcgtacgaggacgcatcggagcgcctgtccgccgaa
aaagccctggagtacatgggattggcggccggacagccgctgaactccatcacggtggac
accgtcttcgtaggttcctgcaccaacggccgcatcgaggacctgcgggccgccgccggg
attctcaaggaccgcaaagtcgccgacggcgtacggatgctggtcgtccccggctccgcg
cgggtgggcctccaggccgtctccgagggcctggacgtggtcttcaaggaggccggcgcc
gaatggcggcacgcgggctgctcgatgtgcctcggcatgaaccccgaccagctggccccg
ggcgagcgctccgcctccacctccaaccgcaacttcgagggccggcagggcaagggcggc
cgcacccatctggtctccccgcaggtcgccgccgccaccgcggtcctcggccatctggcc
tccccggccgatctgtccgacgcccccgcgcccgcaggagtctga
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