Streptomyces noursei ATCC 11455: SNOUR_22540
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Entry
SNOUR_22540 CDS
T04806
Name
(GenBank) uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
snr
Streptomyces noursei ATCC 11455
Pathway
snr00860
Porphyrin metabolism
snr01100
Metabolic pathways
snr01110
Biosynthesis of secondary metabolites
snr01120
Microbial metabolism in diverse environments
snr01240
Biosynthesis of cofactors
Module
snr_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
snr_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
snr00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
SNOUR_22540
Enzymes [BR:
snr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
SNOUR_22540
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
SNOUR_22540
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Gene cluster
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Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
ANZ17781
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Position
5108183..5109844
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AA seq
553 aa
AA seq
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MNPTAPNHSASGQVTFLGAGPGDPGLLTLRAVEALASADVLIADPQVLDVVRVHARAQVD
TPLQASADEASIPGSPHGVSALRDTANLVMAAARAGKRVIRAVTGDPGLDGYVAEEMLAC
AAEGIVFEVVPGIAAAVGVPAYAGVPLRDAQGTDVRFIDARSADDRCWSELGTSDATAVV
STSLDSVAAAAGELVAAGRKPDTPMTVTVAGTTTRQRTWTATLGSVAQVLKAAKVLPSPD
GGQPVIAVVGERSAAAQRDQLSWFENKPLFGWRVLVPRTKEQAASLSDQLVSYGAVPHEV
PTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKVA
AVGEQTAKALVAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATETLV
AGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHN
VTVIACIGPATAKTAEEHGLRVDVMSPEPSVHKLAEALAEFGAARRDAALEAGDPVTRPS
ERRPGARRRRATP
NT seq
1662 nt
NT seq
+upstream
nt +downstream
nt
ttgaaccccaccgccccaaaccactccgcctccggtcaggtcaccttcctgggtgccggg
ccgggagacccgggtctgctgacgctgcgcgccgtggaagcgctggcctccgcggacgtc
ctcatcgccgacccgcaggtcctggacgtcgtgcgtgtgcacgcacgcgcacaggtggac
actccactgcaggcgtcagctgacgaggcgtcaatccccggcagtccccatggcgtttcc
gcccttagggacaccgccaatcttgtcatggcggctgcccgcgcgggcaagcgggtcatc
cgtgcggtgaccggtgaccccggcctcgacggctacgtcgccgaggagatgctggcctgc
gccgccgagggcatcgtcttcgaggtggtccccggcatcgccgccgcggtcggcgtgccc
gcgtacgccggtgtgccgctgcgcgacgcccagggcaccgacgtgcgcttcatcgacgcc
cgcagcgccgacgaccgctgctggtccgagctgggcaccagtgacgccaccgcggtggtc
tccaccagcttggactcggtggccgcggccgccggcgagctggtggccgccggccgcaag
ccggacaccccgatgaccgtcacggtcgccggcaccaccacccggcagcgcacctggacc
gccaccctcgggagcgtcgcccaggtgctgaaggccgccaaggtgctgccgtcgccggac
ggcggccagccggtcatagccgtggtcggcgagcgcagcgccgcggcgcagcgggaccag
ctctcgtggttcgagaacaagccgctgttcggctggcgggtgctggtgccgcggaccaag
gagcaggccgcgtcgctctccgaccagctcgtctcgtacggcgcggtgccgcacgaggtc
ccgaccatcgccgtcgaaccgccgcgcaccccgcagcagatggagcgcgcggtcaagggc
ctggtcaccggccgctacgagtggatcgccttcacctcggtcaacgccgtcaaggccgtc
cgggagaagttcgaggagtacgggctggacgcccgggcgttcgccgggatcaaggtcgcg
gcggtcggcgagcagaccgccaaggcgctggtggccttcggcgtgaagcccgacctggtg
ccgtccggcgagcagtccgcggccgggctgctggaggactggccgccctacgacccggtc
ttcgacccgatcgaccgcgtcttcctgccgcgcgccgacatcgccaccgagacgctggtg
gccggcctgatcgagctgggctgggaggtcgacgacgtcaccgcctaccggaccgtgcgc
gcctcgccgccgccggccgagacccgtgaggcgatcaagggcggcggcttcgacgcggtg
ctcttcacctcgtcctcgaccgtgcggaacctcgtcggcatcgccggcaagccgcacaac
gtgaccgtgatcgcgtgcatcggcccggccaccgccaagacggccgaggagcacgggctg
cgggtggacgtgatgtcgcccgagccgtcggtccacaagctggccgaggcgctcgcggag
ttcggcgcggcgcggcgcgacgccgcgctggaggccggcgacccggtgacgcggccgagc
gagcggcgcccgggtgcccgccggaggcgagccaccccgtag
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