Streptomyces olivoreticuli: QZH56_19490
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Entry
QZH56_19490 CDS
T09517
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sov
Streptomyces olivoreticuli
Pathway
sov00860
Porphyrin metabolism
sov01100
Metabolic pathways
sov01110
Biosynthesis of secondary metabolites
sov01120
Microbial metabolism in diverse environments
sov01240
Biosynthesis of cofactors
Module
sov_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
sov_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sov_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sov00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
QZH56_19490
Enzymes [BR:
sov01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
QZH56_19490
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
QZH56_19490
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
WKK21061
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Position
4429090..4430739
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AA seq
549 aa
AA seq
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MNPTAPNHPVHGHVTFLGAGPGDPGLLTLRAVEALAAADVLIADPQVLDVVRAHARAHVD
MPAQTVTDESSKTADVPVLRDTANLVMTAARGGKRVVRAVLGDPGLDGNAGDEMLACATE
GITFEVVPGVATAVGVPAYAGVPLRDGKGTDVRFVDARTASATCWSEVGASEVTAVVSTT
LDSVVAAAGELVSAGRKPDTPLTVTVAGTTTRQRTWTATLGTIAQVLKAAKVLPSPDGGQ
PVIAVVGERSAAAQRDQLSWFESKPLFGWNVLVPRTKEQAASLSDQLRSYGAVPSEVPTI
AVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKVAAVG
EQTAKSLVEFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATETLVAGL
IELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHNVTV
IACIGPATAKTAEEHGLRVDVLSPEPSVHKLAEALADFGAARRDAALEAGDPVTRPSERR
PGSRRRARS
NT seq
1650 nt
NT seq
+upstream
nt +downstream
nt
ttgaaccccaccgccccgaaccaccccgtgcacgggcacgtcaccttcctcggtgccggc
cccggagacccgggactgctgacgctgcgcgccgtggaggcactggcggccgcggacgtc
ctgattgccgatccgcaggtgctcgatgtggtgcgcgcgcatgcgcgcgcccatgtggac
atgcctgcccagacggttactgacgagtcatcaaaaaccgctgatgtccctgtccttagg
gacaccgccaatcttgtcatgacggccgcgcgcggcggcaagcgggtcgtccgtgccgtc
ctcggcgaccccggcctcgacggcaacgccggcgacgagatgctggcctgcgccaccgag
ggcatcaccttcgaggtggtgccgggcgtcgcgacggccgtgggcgtgcccgcctacgcc
ggagtgccgctgcgcgacggcaagggcaccgacgtgcgcttcgtggacgcccgtacggcc
tcggccacctgctggtccgaggtcggcgcgagcgaggtcaccgcggtcgtctccaccacc
ctcgactcggtggtggccgcggccggcgagctggtctccgccgggcgcaagcccgacacc
ccgctgaccgtcacggtcgcgggcacgaccacgcgccagcgcacctggaccgccaccctc
ggcacgatcgcccaggtgctcaaggccgcgaaggtgctgccgtccccggacggcggccag
ccggtgatagccgtggtcggcgagcgcagcgcggccgcgcagcgcgaccagctctcgtgg
ttcgagtccaagccgctcttcggctggaacgtgctcgtcccgcggacaaaggagcaggcc
gcgtcgctctccgaccagctccggtcgtacggcgccgtgcccagcgaggtcccgaccatc
gcggtcgagccgccgcgcaccccgcagcagatggagcgcgcggtcaagggcctggtcacc
ggccgctacgagtggatcgccttcacctcggtgaacgcggtcaaggcggtccgcgagaag
ttcgaggagtacgggctcgacgcgcgtgccttcgcgggcatcaaggtcgcggccgtcggc
gagcagaccgcgaagtccctcgtcgagttcggtgtgaagcccgacctcgtgccgagcggc
gagcagtcggccgctgggctgctggaggactggccgccctacgacccggtcttcgacccg
atcgaccgcgtcttcctgccgcgcgccgacatcgccaccgagaccctggtggcggggctg
atcgagctgggctgggaggtcgacgacgtcacggcctaccggaccgtgcgggcctccccg
ccgccggccgagacccgcgaggcgatcaagggcggcggcttcgacgccgtgctcttcacc
tcgtcgtccaccgtgcgcaacctcgtcggcatcgccggcaagccgcacaacgtcaccgtc
atcgcctgcatcggcccggccaccgcgaagaccgcggaggagcacggcctgcgggtggac
gtgctgtcgcccgagccctcggtgcacaagctcgccgaggcgctcgcggacttcggcgcg
gcgcggcgcgatgccgccctggaggccggtgacccggtcacgcgcccgagcgagcgacgg
cccggatcgcgtaggagggcacgcagttga
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