Streptomyces paludis: DVK44_12955
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Entry
DVK44_12955 CDS
T06964
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
spad
Streptomyces paludis
Pathway
spad00860
Porphyrin metabolism
spad01100
Metabolic pathways
spad01110
Biosynthesis of secondary metabolites
spad01120
Microbial metabolism in diverse environments
spad01240
Biosynthesis of cofactors
Module
spad_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
spad_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
spad_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
spad00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
DVK44_12955
Enzymes [BR:
spad01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
DVK44_12955
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
DVK44_12955
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AXG78472
UniProt:
A0A345HP48
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Position
complement(2961943..2963604)
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AA seq
553 aa
AA seq
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MSPTTSDLPACSASGHVTFLGAGPGDPGLLTLRAVEALAGADVLIAEPDVLEVVRSHARA
GVSTPALTVVDDVSAAAGIPAIRDAANIVMEAARGGRRVVRAVTGDPGLDGDAGTEMLAC
AVAGIPFEVVPGVAAAVGVPAYAGVPLRDAQGADVRFVDARTANDRCWAEIGASDGTVVV
SATLETVAGAAGELVAAGRKPDTPLTVTVAGTTTRQRTWNATLGTIAQILKQAKVLPSPE
GHRPVIAVVGERSAAAQRDQLAWFESKPLFGWKVLVPRTKEQAASLSDQLRSYGAVPHEV
PTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKVA
AVGEQTAASLIDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATETLV
AGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHN
VTVIACIGPATAKTAEEHGLRVDVLSPEPSVHKLAEALAAFGAQRRLAAKEAGETVTRPS
ERRPGSRRRRTTT
NT seq
1662 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccacctctgaccttccggcctgctccgcatcggggcacgtcaccttccta
ggtgccggacccggagatccgggtctgctgacactccgcgccgtcgaggcgctcgcgggt
gctgacgtactgatcgccgagcctgatgtgctcgaagtcgtacggagccatgcgagggcg
ggtgtgagcacccccgcgctgacggttgtggacgatgtgtcagcagccgccgggatcccc
gcgatccgggatgcggccaatattgtcatggaggccgcgcggggcggcaggcgggtggtc
cgtgcggtcacgggcgacccggggctggacggtgacgcgggcaccgagatgctggcctgc
gctgtcgccggcatccccttcgaggtcgttccgggcgtcgccgccgcggtcggtgtgccg
gcgtacgccggagtgccgctgcgcgacgcccagggcgcggacgtccggttcgtcgacgcc
aggacggccaacgaccgctgctgggccgagatcggcgccagcgacggcacggtcgtggtc
tccgccaccctggagacggtcgccggcgccgccggtgagctggtcgcggccggccgtaaa
ccggacaccccgctgaccgtcaccgtcgcggggacgaccacccgccagcggacgtggaac
gccacgctcggcaccatcgcgcagatcctcaagcaggcgaaggtgctgccctccccggag
ggccaccggcccgtcatagccgtggtcggcgagcgcagcgcggcggcccagcgcgaccag
ctcgcgtggttcgagtccaagccgctgttcggctggaaggtcctcgtgccgcgcaccaag
gagcaggccgcgtcgctctccgaccagctcaggtcgtacggcgcggtcccgcacgaggtg
ccgacgatcgcggtcgagccgccgcgtacgccccagcagatggagcgggccgtcaagggc
ctggtcaccgggcggtacgagtggatcgccttcacctcggtcaacgcggtcaaggcggtg
cgcgagaagttcgaggagtacgggctcgacgcgcgcgccttcgccgggatcaaggtcgcc
gcggtcggcgagcagacggccgcctcgctgatcgacttcggcgtgaagcccgacctcgta
ccctccggggagcagtccgcggccgggctgctggaggactggccgccgtacgacccggtc
ttcgacccgatcgaccgggtgttcctgccgcgcgccgacatcgccacggagacgctggtg
gcgggcctgatcgagctgggctgggaggtcgacgacgtcaccgcgtaccgcacggtgcgc
gcctcgccgccgccggccgagacccgtgaggcgatcaagggcggcggcttcgacgccgtg
ctcttcacctcctcctcgaccgtacggaacctggtcgggatcgcgggcaagccgcacaac
gtgacggtgatcgcctgtatcggcccggcgacggcgaagaccgcggaggagcacggtctg
cgcgtcgacgtcctgtcgcccgagccgtcggtgcacaagctggcggaggccctggccgcg
ttcggcgcgcagcgccggctggcggcgaaggaagccggtgaaacggtcacccgcccgagc
gagcgccgtcccggcagccgcagaaggcgtacgacgacctga
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