Streptomyces parvulus: Spa2297_02895
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Entry
Spa2297_02895 CDS
T04685
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
spav
Streptomyces parvulus
Pathway
spav00290
Valine, leucine and isoleucine biosynthesis
spav00660
C5-Branched dibasic acid metabolism
spav01100
Metabolic pathways
spav01110
Biosynthesis of secondary metabolites
spav01210
2-Oxocarboxylic acid metabolism
spav01230
Biosynthesis of amino acids
Module
spav_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
spav00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Spa2297_02895
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Spa2297_02895
Enzymes [BR:
spav01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
Spa2297_02895
4.2.1.35 (R)-2-methylmalate dehydratase
Spa2297_02895
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
ANJ06021
UniProt:
A0A191UTH7
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Position
complement(643850..645274)
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AA seq
474 aa
AA seq
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MSAAPATIIDKLWDGAVVCTEPDGPDLLYVDLHLVHEATSPQAFEGLRLSGHKVRRPDLT
LAVEDHNVPTDSLTVSDALGREQLETLRRNCADHGIALFPHGHRRQGVVHVVGPELGLVQ
PGMTVVCGDSHTSTHGAFGALAFGVGTSDVEHVLATQTVAVQKPRTMLVEFTGTPADGVT
AKDLMLALITRIGANGAHGHVVEYRGDAVRALSMESRMTMCNLSVEAGARAGLIAPDETT
FAYLAGRPGSPAGPAGREAVAHWRTLASDPGAVFDRTVTVDVSGLTPWVTWGTNPGQAVP
MAGTVPDPAAFTDPDERAAARRALDYMDLAPGTPMRDIAVDTVFIGSCTNGRLDDLRAAA
EVLRGRRVHDGVRVLVVPGSMDVRVHAEREGLHDVFTAAGAEWRLPGCSMCLGMNSDRLP
GSQRCASTSNRNYEGRQGPRARTHLVSPAVAAATAVAGRLALPADLPRGDQWNR
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcggccccggcgacgatcatcgacaagctctgggacggcgccgtcgtgtgcacc
gaacccgacgggcccgacctgctctacgtcgacctgcacctggtccacgaggcgacctcg
ccgcaggcgttcgagggcctgcggctgagcggccacaaggtgcgccgcccggacctgaca
ctcgccgtcgaggaccacaacgtcccgaccgactcgctgaccgtctccgacgccctcggc
cgggagcagctggagaccctgcgccgcaactgcgccgaccacggcatcgcgctgttcccg
cacggccaccgccggcagggcgtggtccacgtcgtcggccccgaactcggcctggtgcag
cccggcatgaccgtggtgtgcggagacagccacacctccacgcacggggccttcggcgcc
ctcgccttcggggtgggcaccagcgacgtcgaacacgtcctcgccacccagacggtggcc
gtgcagaagccccgcacgatgctcgtggagttcaccgggacaccggcggacggcgtcacg
gccaaggacctgatgctggccctcatcacccggatcggcgccaacggcgcgcacggccac
gtcgtggagtaccggggcgacgccgtacgcgcgctctccatggagagccggatgacgatg
tgcaacctcagcgtggaggccggggccagggccgggctgatcgcccccgacgagacgacc
ttcgcctacctcgcgggcaggcccggcagccccgcgggcccggccgggcgggaggcggtc
gcccactggcgcaccctggcgagcgaccccggcgccgtcttcgaccgcacggtgaccgtg
gacgtctcgggcctgaccccgtgggtgacctggggcaccaaccccggccaggccgtaccg
atggcgggcaccgtgcccgaccccgcggccttcaccgaccccgacgagcgggcggcggca
cgccgcgccctcgactacatggacctcgcccccggcacgccgatgcgggacatcgccgtc
gacacggtcttcatcggctcctgcaccaacggccggctggacgatctgcgggccgccgcc
gaggtactgcgcggccgccgggtccacgacggcgtgcgcgtcctggtggtgcccggttcc
atggacgtccgcgtccacgccgaacgcgagggactgcacgacgtcttcaccgccgccggg
gccgagtggcgcctgccgggctgctccatgtgcctcggcatgaacagcgaccggctcccc
ggcagccagcgctgcgcctcgaccagcaaccgcaactacgagggcaggcagggaccccgg
gcgaggacccacctggtgtcgcccgccgtcgccgccgccaccgcggtcgccggccggctg
gcactgcccgccgaccttccccgaggagaccagtggaaccgctga
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