Streptomyces parvulus: Spa2297_18595
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Entry
Spa2297_18595 CDS
T04685
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
spav
Streptomyces parvulus
Pathway
spav00860
Porphyrin metabolism
spav01100
Metabolic pathways
spav01110
Biosynthesis of secondary metabolites
spav01120
Microbial metabolism in diverse environments
spav01240
Biosynthesis of cofactors
Module
spav_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
spav_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
spav_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
spav00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Spa2297_18595
Enzymes [BR:
spav01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Spa2297_18595
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Spa2297_18595
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GFIT
Motif
Pfam:
HEM4
TP_methylase
RodZ_C
Motif
Other DBs
NCBI-ProteinID:
ANJ08804
UniProt:
A0A191V1C7
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Position
4090062..4091759
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AA seq
565 aa
AA seq
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MSPTTFPAGPEHGHVTFLGAGPGDPGLLTLRAVEALSHADVLVAEHEVLDVVRTHARQGV
SEVHTDADPSDPGTGAPQLKVVDGASTTSGVPAVRDAAHLVMEAARGGRRVVRAVTGDPG
LDAYAAEEMLACAAAGVPFEVVPGIANAVGVPAYAGVPLRDAEGADVRFVDARTASGRCW
TEVGASDGTVVVSTTLDSVAAAAGELVSAGRKPDTPLTVTIAGTTTRQRTWTATLGTVAQ
TLKQAKVLPSPDGGRPVIAVVGERSAPARRDQLSWFESKPLFGWKVLVPRTKEQAASLSD
QLTSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYG
LDARAFAGIKVAAVGEQTANALVAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVF
LPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPATTREAIKGGGFDAVLFTSSSTV
RNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVLKLAEALADFGNRRRAA
ALEAGDPVTRPSERRPGARRRRSST
NT seq
1698 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccacctttcccgccggtccggaacacgggcacgtcaccttcctgggtgcc
ggacccggagatccgggactgctgactctgcgcgccgtggaggcgctgtcgcacgcggac
gtcctcgtcgccgagcacgaggtgctcgacgtcgtacgcacgcacgcccggcagggcgtg
tccgaggtgcacacggatgccgatccgtcggatccgggcacaggcgcgccccagctgaag
gtagttgacggagcgtcaacgacctcgggcgtccccgccgtgcgggatgccgcacatctt
gtcatggaggccgcgcggggcggcaggcgggtcgtgcgtgcggtgaccggtgaccccggg
ctcgacgcgtacgccgccgaggagatgctggcctgcgccgcggccggggtgcccttcgag
gtggtcccgggcatcgcgaacgccgtcggcgtgcccgcgtacgccggtgtgccgctgcgg
gacgccgagggcgccgacgtgcggttcgtggacgcccgtacggcttccggccggtgctgg
accgaggtcggtgcctcggacggcacggtcgtcgtctcgacgacgctggactcggtggcc
gcggccgcgggtgagctggtgtcggcgggccgcaagccggacacgccgctgacggtgacg
atcgccggcacgacgacccggcagcggacctggaccgccacgctcggcacggtcgcgcag
acgctgaagcaggcgaaggtgctgccgtcgccggacggcggccgcccggtgatagccgtg
gtcggtgagcgctccgcccccgcccgccgcgaccagttgtcgtggttcgagtccaagccg
ctgttcggctggaaggtcctcgtgccgcggacgaaggagcaggcggcgtcgctctccgac
cagctgacgtcctacggcgccgtgccgcacgaggtcccgaccatcgcggtggagccgccg
cgcaccccgcagcagatggagcgggcggtcaagggcctggtcacgggccgctacgagtgg
atcgcgttcacctcggtcaacgcggtgaaggcggtccgggagaagttcgaggagtacggg
ctcgacgcccgcgccttcgccgggatcaaggtcgccgcggtcggcgagcagacggccaac
gcgctcgtcgccttcggcgtgaagccggacctggtgccgagcggcgagcagtccgcggcc
ggtctgctggaggactggccgccctacgacccggtcttcgacccgatcgaccgcgtcttc
ctgccccgggccgacatcgccacggagaccctggtggccgggctgatcgagctgggctgg
gaggtcgacgacgtcacggcctaccggacggtgcgcgcctcgccgccgccggccaccacc
cgcgaggcgatcaagggcggcggcttcgacgcggtgctcttcacgtcgtcgtcgacggtc
cgcaacctggtcggcatcgcgggcaagccgcacaacgtcacggtgatcgcgtgcatcggc
ccggcgacggccaagacggccgaggagcacggtctgcgggtcgacgtcatggccccggag
ccgtcggtgctgaagctggcggaggccctggccgacttcggcaaccggcgccgcgcggcg
gccctggaggccggcgacccggtgacccggccgagcgaacggcggccgggggcacgcagg
cggcggtcctccacgtga
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