Streptomyces peucetius subsp. caesius: CGZ69_23875
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Entry
CGZ69_23875 CDS
T07792
Name
(GenBank) 2-oxoglutarate dehydrogenase E1 component
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
speu
Streptomyces peucetius subsp. caesius
Pathway
speu00020
Citrate cycle (TCA cycle)
speu00630
Glyoxylate and dicarboxylate metabolism
speu00785
Lipoic acid metabolism
speu01100
Metabolic pathways
speu01110
Biosynthesis of secondary metabolites
speu01120
Microbial metabolism in diverse environments
speu01200
Carbon metabolism
speu01210
2-Oxocarboxylic acid metabolism
Module
speu_M00009
Citrate cycle (TCA cycle, Krebs cycle)
speu_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
speu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
CGZ69_23875
00630 Glyoxylate and dicarboxylate metabolism
CGZ69_23875
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CGZ69_23875
Enzymes [BR:
speu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
CGZ69_23875
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
CGZ69_23875
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
CGZ69_23875
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
CGZ69_23875
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Gene cluster
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Motif
Pfam:
E1_dh
Transket_pyr
2-oxoacid_dh
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
ATW52812
LinkDB
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Position
complement(5188747..5192550)
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AA seq
1267 aa
AA seq
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MSSQSPSNSSLSTDQAGQGQNPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GAAATADAPAAGAKQTQGDGAAPAPAPAAAAPAQPAAPAQPAAQAPAPAAPAAPAKAAPA
PAPAQPAKPAATKPAPAAKADAQPADGPEFVTLRGPAAAVAKNMNASLELPTATSVRAVP
VKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNWSFAEKDGKPTLVKPD
HVNFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVRRARNNKLTMDDFTGVT
VSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTY
DHRVIQGAASGEFLRIVANFLLGEENFYDEIFESLRIPYEPVRWLKDIDASHDDDVTKAA
RVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAVGGFAGKSMMK
LRDILGVLRESYCRTTGIEFMHIQDPKQRKWLQDRVERATTKPEREEQLRILRRLNAAEA
FETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVG
KSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHLEAVDPV
LEGVARAKQDVINKGGTDFTVLPIALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHVVI
NNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVV
IDLICYRRRGHNEGDNPQFTNPQMYNLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDF
QGQLEKVFAEVREATSHPAPAHVPDAEAEFPVAINTAVSQEVVKRIAESQVNIPDHITVH
PRLMPQMQRRAASVEDGTIDWGMGETLAIGSLLMEGTPVRLSGQDTRRGTFGQRHAVLVD
QETGEDYTPLLYLSEDQARYNVYDSLLSEYAAMGFEYGYSLARPDALVMWEAQFGDFVNG
AQTVVDEFISSAEQKWGQHSGVTLLLPHGYEGQGPDHSSARPERFLQMCAQDNMTVAMPT
LPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKAEEFTTGGFRPVIGDDSVDPAA
VRKVVFCAGKVYYDLEAERQKRGVTDTAIIRLERLYPLPGAELQAEIAKYPNAEKYLWTQ
EEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSAKRHQAEQQQL
VNEVFDA
NT seq
3804 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctcagtcccccagtaactcgagtctctcgaccgaccaagccgggcagggtcag
aaccctgccgctgcattcggcgccaatgagtggctcgtcgacgagatctaccagcagtac
ctccaggacccgaattcggtcgaccgtgcctggtgggacttcttcgccgactacaagccg
ggagcggccgccaccgcggacgcccccgccgctggagcgaagcagactcagggcgacgga
gccgcgccggctcccgccccggccgccgccgctccggcgcaacccgcagccccggcacag
cccgccgcccaggcgccggctcccgcggctcccgcggctcccgccaaggctgctcccgcg
cccgccccggcacagccggcgaagcccgccgcgaccaagccggccccggccgccaaggcc
gatgcccagccggccgacggccccgagttcgtgacgctgcgcggcccggccgccgcggtc
gcgaagaacatgaacgcctccctggagctgcccacggccacgtccgtgcgcgccgtcccg
gtgaagctgctcttcgacaaccgcatcgtcatcaacaaccatctcaagcgcgcccgtggc
gggaagatctccttcacccacctcatcgggtacgcgatggtgcaggccatcaaggccatg
ccgtcgatgaactggtccttcgccgagaaggacggcaagccgaccctggtcaagcccgac
cacgtgaacttcggtctggccatcgacctggtgaagccgaacggcgaccgccagctggtc
gtcgcgggcatcaagaaggccgagacgctgaacttcttcgagttctggcaggcctacgag
gacatcgtccgccgcgcccgcaacaacaagctgacgatggacgacttcaccggcgtcacc
gtctcgctgaccaaccccggcggcctcggcaccgtccactccgtgccgcgtctgatgccc
ggccagtcggtcatcatgggcgtcggctcgatggactacccggccgagttccagggcacc
tcccaggacaccctgaacaagctgggcatctccaaggtgatgaccctcacctcgacgtac
gaccaccgggtcatccagggcgccgcgtcgggcgagttcctgcggatcgtcgccaacttc
ctcctcggcgaggagaacttctacgacgagatcttcgagtcgctgcgcatcccctacgag
ccggtccgctggctcaaggacatcgacgcctcgcacgacgacgacgtcaccaaggccgcc
cgcgtcttcgagctgatccactcctaccgggtccgcggtcacgtcatggccgacaccgac
ccgctggagtaccgccagcgcaagcaccccgacctggacatcaccgagcacggcctcacg
ctctgggacctggagcgcgagttcgccgtcggcggcttcgccggcaagtcgatgatgaag
ctgcgcgacatcctgggcgtgctgcgtgagtcgtactgccgcaccacgggcatcgagttc
atgcacatccaggacccgaagcagcgcaagtggctgcaggaccgggtcgagcgcgccacc
accaagccggagcgcgaggagcagctgcgcatcctgcgccggctgaacgcggcggaggcc
ttcgagaccttcctgcagaccaagtacgtcggccagaagcgcttctcgctggagggcggc
gagtccgtcatcccgctgctcgacgcggtcatcgactcggccgccgagtcgcgcctcgac
gaggtcgtcatcggcatggcccaccgcggccggctcaacgtgcttgcgaacatcgtcggc
aagtcgtacgcccagatcttccgggagttcgagggcaacctcgacccgaagtcgatgcac
ggctccggcgacgtgaagtaccacctgggcgccgagggcaccttcaccggcctcgacggc
gagcagatcaaggtctccctggtcgccaacccctcccacctggaggccgtcgacccggtc
ctcgaaggtgtcgcccgcgccaagcaggacgtcatcaacaagggcggcacggacttcacg
gtcctgccgatcgccctgcacggtgacgcggccttcgccggccagggtgtcgtcgccgag
acgctgaacatgtcgcagctgcgcggctaccgcaccggcggcacggtccacgtcgtcatc
aacaaccaggtcggcttcacggccgcgccggagtcctcccgctcctccatgtacgcgacc
gacgtcgcccgcatgatcgaggcgccgatcttccacgtgaacggcgacgacccggaggcc
gtggtccgcgtcgcgcggctcgccttcgagttccgccaggcgttcaacaaggacgtcgtg
atcgacctcatctgctaccgccgccgcggtcacaacgagggcgacaacccgcagttcacc
aacccgcagatgtacaacctgatcgacaagaagcgttcggtgcgcaagctctacaccgag
tcgctcatcggtcgcggcgacatcacgctggaagaggccgagcaggcgctccaggacttc
cagggccagctggagaaggtcttcgcggaggtccgcgaggccaccagccacccggccccg
gcccatgtcccggacgccgaggccgagttcccggtcgcgatcaacacggcggtctcccag
gaggtcgtcaagcggatcgccgagtcccaggtcaacatccccgaccacatcaccgtgcac
ccgcggctcatgccgcagatgcagcgccgcgcggcgtccgtcgaggacggcacgatcgac
tggggcatgggcgagaccctcgccatcggctcgctgctgatggagggcacccccgtccgg
ctctccggccaggacacccgccgcggcacgttcggccagcgccacgcggtgctggtggac
caggagaccggcgaggactacaccccgctgctctacctgtccgaggaccaggcccgctac
aacgtctacgactcgctgctcagcgagtacgcggcgatgggcttcgagtacggctactcg
ctggcccgcccggacgcgctggtcatgtgggaggcgcagttcggtgacttcgtcaacggc
gcgcagaccgtggtcgacgagttcatctcctccgccgagcagaagtggggccagcactcc
ggcgtcacgctgctcctgccgcacggctacgagggccagggcccggaccactcgtccgcg
cgtcccgagcgcttcctgcagatgtgcgcgcaggacaacatgacggtcgccatgccgacc
ctgccgtcgaactacttccacctgctgcgctggcaggtccacaacccgcaccacaagccg
ctgatcgtcttcaccccgaagtcgatgctgcgtctgaaggccgcggcgtccaaggcggag
gagttcaccaccggcggcttccgcccggtgatcggcgacgactcggtcgacccggcggcc
gtccgcaaggtcgtcttctgcgccggcaaggtctactacgacctcgaggcggagcgtcag
aagcgcggcgtcacggacacggcgatcatccgactcgagcgtctgtacccgctgccgggt
gcggagctccaggcggagatcgccaagtaccccaacgccgagaagtacctgtggacgcag
gaggagccggcgaaccagggtgcctggccgttcatcgcgctcaacctgatcgaccacctc
gacctggccgtcggcgcggacgtcccgcacggcgagcgccttcgccgcatctcgcgcccc
cacggctcgtccccggccgtcggctccgcgaagcgccaccaggcggagcagcagcagctg
gtcaacgaggtcttcgacgcgtga
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