Streptomyces phaeolivaceus: F9278_35170
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Entry
F9278_35170 CDS
T07107
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sphv
Streptomyces phaeolivaceus
Pathway
sphv00290
Valine, leucine and isoleucine biosynthesis
sphv00660
C5-Branched dibasic acid metabolism
sphv01100
Metabolic pathways
sphv01110
Biosynthesis of secondary metabolites
sphv01210
2-Oxocarboxylic acid metabolism
sphv01230
Biosynthesis of amino acids
Module
sphv_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sphv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
F9278_35170 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
F9278_35170 (leuC)
Enzymes [BR:
sphv01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
F9278_35170 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
F9278_35170 (leuC)
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Gene cluster
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
QFR00549
UniProt:
A0A5P8KCN4
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All DBs
Position
7621809..7623239
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AA seq
476 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKSGRKVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRVQLETLRANAAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GMTVVCGDSHTSTHGAFGGLAFGIGTSQVEHVLATQTLPLVRPKTMAITVEGELADGVTA
KDLILAIIARIGTGGGQGYVLEYRGPAIEQLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLKGRPHAPEGEDWDAAVAYWRTLRTDDDAEFDAEVIIDGTTLAPFVTWGTNPGQGAPL
SASVPDPASYEDASERLAAEKALEYMGLEAGQPLKSINVDTVFVGSCTNGRIEDLRAAAE
LIKGRKVADGVRMLVVPGSARVGLQAVSEGLDIVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLTDATAPAPAGV
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccccaggcc
ttcgacggtctccgcaagagcgggcgcaaggtgcgccggctcgacctgaccatcgcgacc
gaggaccacaacacccccacccttgacatcgacaagcccatcgcggacccggtctcccgc
gtacagttggagacactgcgcgccaacgccgccgagttcggtgtgcggctgcacccgctg
ggcgacgtcgagcagggtgtcgtgcacgtcgtcggcccgcagctgggtctgacccagccg
ggcatgaccgtcgtctgcggcgactcccacacctccacgcacggcgccttcggcggtctg
gcgttcggtatcggcacctcccaggtggagcatgtgctggccacccagacgctgccgctg
gtccgccccaagaccatggccatcaccgtcgagggcgagctggccgacggcgtcaccgcc
aaggacctgatcctggcgatcatcgccaggatcggcacgggcggcggccagggctatgtc
ctggagtatcgcggtcccgccatcgagcagctctcgatggaggcccggatgaccatctgc
aacatgtccatcgaggccggcgcccgtgcgggcatgatcgcccccgacgagaccaccttc
gcgtacctcaagggccgcccgcacgcccccgagggcgaggactgggacgcggccgtcgcg
tactggcggacgctgcggacggacgacgacgccgagttcgacgccgaggtgatcatcgac
ggcaccacgctggcgccgttcgtcacctggggcaccaaccccggccagggcgcgccgctt
tcggcgtccgtccccgacccggcttcgtacgaggacgcttcggagcgcctcgccgccgaa
aaggccctggagtacatggggttggaggccggccagccgctgaagtccatcaacgtggac
accgtcttcgtaggttcgtgcaccaacggccgcatcgaggacctgcgcgccgccgccgag
ctgatcaagggccgcaaagtcgccgacggcgtacggatgctggtcgtcccgggctccgcg
cgggtcggtctgcaggccgtctccgagggcctggacatcgtcttcaaggaggccggcgcc
gagtggcggcacgcgggctgctcgatgtgtctgggcatgaacccggaccagctggccccg
ggtgagcgctccgcgtccacctccaaccgcaacttcgaggggcggcagggcaagggcggc
cgtacccacctggtctccccgcaggtcgccgccgcgacggccgtgctgggccatctggcg
tcccccgccgacctgaccgacgccaccgcccccgcgcccgctggagtctga
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