Streptomyces phaeoluteigriseus: NFX46_02785
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Entry
NFX46_02785 CDS
T08568
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sphw
Streptomyces phaeoluteigriseus
Pathway
sphw00860
Porphyrin metabolism
sphw01100
Metabolic pathways
sphw01110
Biosynthesis of secondary metabolites
sphw01120
Microbial metabolism in diverse environments
sphw01240
Biosynthesis of cofactors
Module
sphw_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
sphw_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sphw_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sphw00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
NFX46_02785
Enzymes [BR:
sphw01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
NFX46_02785
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
NFX46_02785
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
USQ82789
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Position
603637..605340
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AA seq
567 aa
AA seq
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MSPTTLPAGPEHGHVTFLGAGPGDPGLLTLRAVEALAHADVLVAEHEVLDVVRTHARPGV
TVVHAEAGPYSGPLPGTGTPHPTVVDGTSTTAGSPAVRDAAHLVMEAARGGRRVVRAVSG
DPGLDTYAAEEMLACVAAGVPFEVVPGIAAAVGVPAYAGVPLRDAQGADVRFIDARTASD
RCWTEVGVSDGTVVVSTSLDSVAAAAGELVAAGRKPDTPMTVTVAGTTTRQRTWSATLGT
IAQTLKQAKVLPSPEGGRPVIAVVGERSAPAQRDQLAWFESKPLFGWKVLVPRTKEQAAS
LSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFE
EYGLDARAFAGIKVAAVGEQTAKALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPID
RVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSS
STVRNLVGIAGKPHNVTIIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALAEFGLRR
RAAAREAGDPVSRPSERRPGARRRRAT
NT seq
1704 nt
NT seq
+upstream
nt +downstream
nt
gtgagccccaccactcttcccgccggtccggaacacgggcacgtcaccttcctgggtgcc
ggacccggggatccgggactgctgactcttcgcgccgtggaggcgctggcgcacgcggac
gtcctcgtcgccgagcacgaggtgctcgacgtcgtccggacgcacgccaggcccggcgtc
accgtcgtgcacgcggaagccggcccgtattcgggccctcttccgggcacgggcacgccg
cacccgacggtcgttgacggcacgtcaacaaccgctgggagccccgctgtgcgggatgcc
gcacatcttgtcatggaggccgcacggggcggcaggcgggtcgtccgcgcggtgtccggg
gacccgggactggatacgtacgcggccgaggaaatgctcgcctgcgtggcggccggtgtt
cccttcgaggtcgtccccggcatcgcggccgccgtcggcgtgcccgcgtacgccggtgtg
ccgctgcgcgacgcgcagggcgcggacgtccggttcatcgacgcgcggaccgcgtccgac
cggtgctggaccgaggtcggcgtgtccgacgggaccgtcgtcgtgtccacgtcgctggac
tccgtggccgccgccgccggtgaactggtcgcggccgggcgcaagcccgacaccccgatg
accgtcaccgtcgccggtacgacgacccgtcagcggacctggagcgccaccctcggcacc
atcgcgcagacgctgaagcaggcgaaggtgctgccgtctcccgagggcggccggccggtc
atagccgtggtcggtgagcgttccgcccccgcccagcgcgaccagctcgcctggttcgag
tccaagccgctgttcggctggaaggtgctcgtaccgcgcaccaaggagcaggcggcatcg
ctctccgaccagctgcggtcctacggcgccgtgccgcacgaggtgccgaccatcgccgtc
gagccgccgcggacgccccagcagatggagcgggccgtcaaggggctggtgaccggacgg
tacgagtggatcgccttcacctcggtgaacgcggtcaaggccgtacgggagaagttcgag
gagtacgggctcgacgcccgcgccttcgccgggatcaaggtcgcggcggtgggcgagcag
accgccaaggcgctgatcgcgttcggtgtgaagccggacctggtgccgagcggggagcag
tccgcggccgggttgctggaggactggcctccctacgacccggtgttcgacccgatcgac
cgggtgttcctgccgcgggccgacatcgccaccgagacgctcgtcgccgggctcatcgaa
ctcgggtgggaggtcgacgacgtcaccgcctaccggaccgtgcgggcctcgccgccgccg
gccgagacgcgggaggcgatcaagggcggtgggttcgacgccgtgctgttcacgtcgtcg
tccaccgtgcggaacctggtcgggatcgcggggaagccgcacaacgtgacgatcatcgcg
tgcatcgggccggctacggccaagacggccgaggagcacgggctgcgggtggatgtgatg
gctcccgagccgtccgtgcacaagttggccgaggcgttggcggagttcgggctgcggcgg
cgggccgccgcgcgggaggccggggacccggtcagccggccgagcgagcggcggccgggg
gcgcggagacgccgggctacctga
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