Streptomyces platensis: CP981_18125
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Entry
CP981_18125 CDS
T07341
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
spla
Streptomyces platensis
Pathway
spla00860
Porphyrin metabolism
spla01100
Metabolic pathways
spla01110
Biosynthesis of secondary metabolites
spla01120
Microbial metabolism in diverse environments
spla01240
Biosynthesis of cofactors
Module
spla_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
spla_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
spla00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CP981_18125
Enzymes [BR:
spla01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CP981_18125
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CP981_18125
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QEV53334
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Position
complement(4124020..4125669)
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AA seq
549 aa
AA seq
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MNPTAPNHSASGQVTFLGAGPGDPGLLTLRAVEALASADVLIADPQVLDVVRVHARAQVD
TPLQASADEASIPADVPALRDTANLVMAAARAGKRVVRAVSGDPGLDGYVAEEMLACAAE
GIVFEVVPGIAAAVGVPAYAGVPLRDAEGTDVRFVDARTADARCWAEVGASDATAVVSTS
LDSVAAAAGELVSAGRKPDTPLTVTVAGTTTRQRTWTATLGSVAQVLKAAKVLPSPDGGQ
PVIAVVGERSAAAQRDRLSWFESKPLFGWRVLVPRTKEQAASLSDQLVSYGAVSHEVPTI
AVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKVAAVG
EQTAKALVAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATETLVAGL
IELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHNVTV
IACIGPATAKTAEEHGLRVDVMSPEPSVHKLAEALADFGAARRDAALEAGDPVTRPSERR
PGSRRRARS
NT seq
1650 nt
NT seq
+upstream
nt +downstream
nt
ttgaaccccaccgccccaaaccactccgcctccggtcaggtcaccttcctgggtgccggg
ccgggagacccgggtctgctgacgctgcgtgccgtggaggcgctggcctccgcggacgta
ctgatcgccgacccgcaggtgctggacgtcgtgcgcgtgcatgcccgcgcacaggtggac
acaccactacaggcatcagctgacgaggcgtcaatccccgccgacgtcccggcccttagg
gacaccgccaatcttgtcatggcggccgcccgtgcgggcaagcgggtcgtacgtgccgtc
agcggagatcccggcctggacgggtacgtcgccgaggagatgctggcctgcgccgccgaa
ggcatcgtcttcgaggtcgtgcccggtatcgccgcggccgtcggcgtgcccgcgtacgcc
ggtgtcccgctgcgggacgccgagggcaccgacgtccgcttcgtcgacgcccgcaccgcc
gatgcgcgctgctgggccgaggtgggtgccagcgacgccaccgccgtcgtctccacctcc
ctcgactcggtggccgcggccgccggtgagctggtgtccgcgggccgcaagcccgacacc
ccgctgaccgtcaccgtcgccggcaccaccacccgccagcgcacctggaccgccaccctc
gggtcggtcgcgcaggtgctcaaggccgccaaggtgctgccgtcgccggacggcggccag
ccggtcatagccgtggtcggtgagcgcagtgccgccgcgcagcgcgaccgcctttcgtgg
ttcgagtccaagccgctcttcggctggcgggtgctcgtgccgcgtacgaaggagcaggcc
gcgtcgctctccgaccagctcgtctcgtacggcgcggtgtcgcacgaggtcccgaccatc
gccgtcgaaccgccgcgcaccccgcagcagatggagcgcgcggtcaagggcctggtcacc
ggccgctatgagtggatcgccttcacctcggtcaacgccgtcaaggccgtccgggagaag
ttcgaggagtacggcctcgacgcccgcgcgttcgccgggatcaaggtcgccgcggtcggc
gagcagaccgccaaggcgctggttgccttcggtgtgaagcccgacctggtgccgagcggt
gagcagtccgccgccggtctgctggaggactggccgccctacgacccggtcttcgacccg
atcgaccgcgtcttcctgccgcgtgccgacatcgccaccgagaccctggtcgccgggctg
atcgagctgggctgggaggtcgacgacgtcaccgcctaccggacggtgcgcgcctcgccg
ccgccggccgagacccgggaagccatcaagggcggcggcttcgacgcggtgctcttcacg
tcctcgtcgaccgtgcggaacctcgtcgggatcgccggcaagccgcacaacgtgacggtg
atcgcctgtatcggcccggccaccgccaagaccgccgaggagcacggactgcgggtggac
gtcatgtcgcccgagccgtcggtgcacaagctggccgaggcgctcgcggacttcggggcg
gcgcgccgcgatgccgcgctggaggccggggacccggtcacccgcccgagcgagcggcgg
cccggctcgcgccggagagcgcgcagctag
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