Streptococcus pneumoniae TIGR4 (virulent serotype 4): SP_0176
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Entry
SP_0176 CDS
T00057
Symbol
ribAB
Name
(GenBank) 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II
KO
K14652
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:
4.1.99.12
3.5.4.25
]
Organism
spn
Streptococcus pneumoniae TIGR4 (virulent serotype 4)
Pathway
spn00740
Riboflavin metabolism
spn00790
Folate biosynthesis
spn01100
Metabolic pathways
spn01110
Biosynthesis of secondary metabolites
spn01240
Biosynthesis of cofactors
Module
spn_M00125
Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD
Brite
KEGG Orthology (KO) [BR:
spn00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00740 Riboflavin metabolism
SP_0176 (ribAB)
00790 Folate biosynthesis
SP_0176 (ribAB)
Enzymes [BR:
spn01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.25 GTP cyclohydrolase II
SP_0176 (ribAB)
4. Lyases
4.1 Carbon-carbon lyases
4.1.99 Other carbon-carbon lyases
4.1.99.12 3,4-dihydroxy-2-butanone-4-phosphate synthase
SP_0176 (ribAB)
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Gene cluster
GFIT
Motif
Pfam:
DHBP_synthase
GTP_cyclohydro2
PucR
Motif
Other DBs
NCBI-ProteinID:
AAK74357
UniProt:
A0A0H2UN41
Structure
PDB
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All DBs
Position
complement(168493..169698)
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AA seq
401 aa
AA seq
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MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTENVNFMATYAKGLICMPM
SESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEERGLTARMCVAEDITPSDF
RRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGLCCEIMNHDGKMMRTDDLIQF
SKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYGNFKAISYIDKLNGEHHLALIMG
NIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKAMKMIVENGSGVLLYLRQEGRGIGL
INKLKAYHLQDQGMDTLDANLALGFEGDLREYHIGAKMLKDLGLQSLHLLTNNPDKVEQL
EKYGITISSRISIEIEANPYDSFYLETKKNRMGHILNMEEK
NT seq
1206 nt
NT seq
+upstream
nt +downstream
nt
atggaatatcgaaaaatacaagaagcattagaagcattgcagaagggacgacttgttctt
gttatagacgacaaggatagagaaaatgaaggagacttaatttgttctgcacaagcagct
acaacagaaaatgttaattttatggctacttatgccaaaggattaatttgtatgcctatg
agcgaaagtttagctaatcaattaatgctttcacctatggttgaaaacaatacagataat
cataagactgcttttacagtttcaattgattataaagaaacgaccacaggtatttctgcc
gaggaaagaggactgaccgcacgtatgtgtgtagctgaagatataacaccctctgatttt
cgcaggccaggacacatgtttcctttaattgcaaaaaaaggtggtgtcctagaaagaaat
ggacacacagaagcaactgttgatttattaaaattagctggactaaaagagtgtggccta
tgttgtgaaataatgaatcatgatggcaaaatgatgagaacagatgatttaattcagttc
tcgaaaaaacacaacattccactaattaccatcaaagaattacaagaatatagaaaagta
tatgatcagctggtagaacgagtttcaactgtcaatatgcctactagatacggtaatttc
aaagcaattagctatatagataaactaaatggggaacatcatcttgctcttattatggga
aatatagaggatgaagccaatgtattatgtcgggtccactccgaatgtttaacaggagat
gttttaggctctttacgttgcgattgtggacagcaattcgataaggctatgaaaatgatt
gttgagaatggttcgggtgtcttactttacttgcgacaggagggacgaggaattggactt
atcaataaattaaaagcctatcatttacaagatcaaggcatggatacgcttgatgccaat
cttgcattaggctttgaaggtgatttaagagaatatcatattggagcaaaaatgcttaaa
gatctgggacttcagtcacttcatttactgacaaataatcctgacaaggttgaacagtta
gaaaaatatggaattaccatttccagtagaatatcaatcgaaatagaagccaatccttac
gatagtttttatttagaaacaaagaaaaatcgaatgggtcacattttaaatatggaggaa
aaataa
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