Streptomyces prasinus: CP972_25220
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Entry
CP972_25220 CDS
T07676
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
spra
Streptomyces prasinus
Pathway
spra00290
Valine, leucine and isoleucine biosynthesis
spra00660
C5-Branched dibasic acid metabolism
spra01100
Metabolic pathways
spra01110
Biosynthesis of secondary metabolites
spra01210
2-Oxocarboxylic acid metabolism
spra01230
Biosynthesis of amino acids
Module
spra_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
spra00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
CP972_25220 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CP972_25220 (leuC)
Enzymes [BR:
spra01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
CP972_25220 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
CP972_25220 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
QEV08487
UniProt:
A0A5J6H404
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Position
5564807..5566234
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AA seq
475 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKSGRTVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRVQLETLRANCAEFGVRLHSLGDVEQGVVHVVGPQLGLTQP
GMTVVCGDSHTSTHGAFGGLAFGIGTSQVEHVLATQTLPLARPKTMAITVEGELPDGVTA
KDLILAVIARIGTGGGQGYILEYRGEAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLEGRPHAPKGEDWDAAVAYWKTLRTDDDAEFDAEVVIDATELSPFVTWGTNPGQGAPL
SAKVPDPASYEDASERLAAEKALEYMGLEAGQPLRSIGVDTVFVGSCTNGRIEDLRAVAE
IVKGRSVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLDTDAPTPAGV
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccacgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccccaggcc
ttcgacggcctccgcaagagcggccgcaccgtgcggcgcctcgacctcaccatcgcgacc
gaggaccacaacaccccgaccctcgacatcgacaagcccatcgccgacccggtctcccgg
gtccagctggagacgctgcgggcgaactgcgccgagttcggcgtccggctgcactcgctg
ggcgacgtcgagcagggcgtcgtgcacgtcgtcggaccccagctgggcctgacccagccc
ggcatgaccgtggtctgcggagactcgcacacctccacgcacggcgcgttcggcggcctg
gccttcggcatcggcacctcccaggtcgagcacgtcctcgccacccagacgctgccgctg
gcccgcccgaagaccatggccatcaccgtcgagggcgaactgcccgacggcgtcacggcc
aaggacctgatcctggcggtcatcgcgcgcatcggcaccggcggcggccagggctacatc
ctggagtaccgcggcgaggccatcgagaagctctcgatggaggcccgcatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagaccacgttc
gcctacctcgagggccgcccgcacgccccgaagggcgaggactgggacgcggccgtcgcc
tattggaagacgctgcgcaccgacgacgacgccgagttcgacgccgaggtcgtcatcgac
gccaccgagctgtccccgttcgtcacctggggcaccaacccgggccagggcgcgccgctg
tcggcaaaggtccccgaccccgcttcgtacgaagacgcctcggagcgcctcgccgccgaa
aaggccctggagtacatggggttggaagccggtcagccgctgcgctccatcggtgtggac
accgtcttcgtaggctcctgcaccaacgggcggatcgaggacctgcgcgccgtcgcggag
atcgtcaagggccgcagcgtcgccgacggggtacggatgctggtcgtcccgggctccgcg
cgggtgggactgcaggccgtctccgagggcctggacgtggtcttcaaggaggccggcgcc
gaatggcggcacgcgggttgctccatgtgcctgggcatgaaccccgaccagctcgccccc
ggtgagcgctccgcctccacctccaaccggaacttcgagggccggcagggcaagggcggc
cgtacccacctggtgtccccgcaggtcgccgccgccaccgcggtcctcggccacctggcc
tccccggccgacctcgacaccgacgcccccacgcccgctggagtctga
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