Streptomyces pristinaespiralis: SPRI_3353
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Entry
SPRI_3353 CDS
T04073
Name
(GenBank) uroporphyrin-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
spri
Streptomyces pristinaespiralis
Pathway
spri00860
Porphyrin metabolism
spri01100
Metabolic pathways
spri01110
Biosynthesis of secondary metabolites
spri01120
Microbial metabolism in diverse environments
spri01240
Biosynthesis of cofactors
Module
spri_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
spri_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
spri_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
spri00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
SPRI_3353
Enzymes [BR:
spri01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
SPRI_3353
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
SPRI_3353
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
ALC21659
UniProt:
A0A0M3QIK5
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All DBs
Position
complement(3908578..3910245)
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AA seq
555 aa
AA seq
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MSPTTSTHPPLPAHGHGHVTFLGAGPGDPGLLTLRAVEALAGADVLVAEPQVLDVVRGHA
RASVSTPELTVVDDVSTTVGIPVLRDAANLVMEAARGGKRVVRAVTGDPGLDTDAGQEML
ACAAAGIPFEVVPGVATAVGVPAYAGVPLRDEQGADVRFIDARTASDRCWSEVGASDGTA
VVSATLETVAAAAGELVAAGRKPDTPLTVTVAGTTTRQRTWTATLGTIAQTLKQAKVLPS
PDGHQPVIAVVGERSAAAQREQLAWFESKPLFGWKVLVPRTKEQAASLSDQLRSYGAVPH
EVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIK
VAAVGEQTAAALVDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATET
LVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKP
HNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVHRLAEALAEFGAARRAAAVEAGEHVTR
PSERRPGGRRRRTTT
NT seq
1668 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccacctcgacccatccgccccttccggcacacggacacgggcacgtcacc
ttcctgggtgccggtcccggcgatcccggtctgctgactctgcgcgccgtcgaggcgctg
gccggcgccgacgtgctggtcgccgagccgcaggtgctcgacgtcgttcgcggccatgcg
cgggcgagcgtgagcacgcctgaactgacggttgttgacgacgtgtcaacaaccgtcggg
atccccgtactcagggatgcggccaatcttgtcatggaggcagcacggggcggcaagcgg
gtcgtccgtgcggtgaccggtgaccccggcctggacaccgacgcaggtcaggagatgctc
gcctgcgccgcggcggggatccccttcgaggtcgtgcccggtgtggcgaccgcggtgggc
gtgcccgcgtacgcgggcgtcccgctccgtgacgagcagggcgcggacgtcaggttcatc
gacgcgcgcaccgcttccgaccgctgctggagcgaggtcggcgccagcgacggcacggcc
gtcgtctccgccacgctcgagacggtcgccgcggcggccggcgagctggtcgcggccggc
cgcaagccggacaccccgctcaccgtcaccgtggccggcacgaccacgcggcagcggacc
tggacggcgacgctcggcacgatcgcgcagaccctgaagcaggcgaaggtgctgccgtcc
cccgacggccaccagccggtcatagccgtggtcggtgagcgcagcgccgcggcacagcgc
gagcagctcgcgtggttcgagtccaagccgctgttcggctggaaggtgctcgtaccgcgc
acgaaggagcaggcggcctcgctctccgaccagcttcgttcctacggcgccgtgccgcac
gaggtcccgacgatcgccgtcgaaccgccgcgcacgccgcagcagatggagcgtgcggtc
aagggcctggtgaccggccgctacgagtggatcgccttcacgtccgtcaacgccgtgaag
gcggtgcgggagaagttcgaggagtacggcctcgacgcccgcgccttcgccgggatcaag
gtcgcggcggtcggcgagcagacggcggccgcgctggtggacttcggcgtgaagccggac
ctggtgccgagcggtgagcagtccgccgccgggctgctggaggactggccgccctacgac
ccggtcttcgacccgatcgaccgcgtcttcctgccgcgcgccgacatcgccaccgagacg
ctggtcgcgggcctcatcgagctcgggtgggaggtcgacgacgtgaccgcctaccggacg
gtgcgtgcgtcgccgccgccggcggagacccgcgaggcgatcaagggcggcggcttcgac
gccgtgctcttcacctcgtcgtcgacggtgcggaacctggtcggcatcgccggcaagccg
cacaacgtgaccgtgatcgcctgcatcggtccggccaccgcgaagaccgcggaggagcac
gggctgcgggtggacgtcctgtcccccgagccgtccgtgcaccggctggccgaggcgctg
gccgagttcggcgcggcccgccgcgccgccgcggtcgaggcgggcgagcacgtgacgcgc
ccgtcggagcgccgtccgggcggccggagacgtcgcacgacgacctga
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