KEGG   Streptomyces qinzhouensis: FQU76_19805
Entry
FQU76_19805       CDS       T06686                                 
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
  KO
K13542  uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
Organism
sqz  Streptomyces qinzhouensis
Pathway
sqz00860  Porphyrin metabolism
sqz01100  Metabolic pathways
sqz01110  Biosynthesis of secondary metabolites
sqz01120  Microbial metabolism in diverse environments
sqz01240  Biosynthesis of cofactors
Module
sqz_M00121  Heme biosynthesis, plants and bacteria, glutamate => heme
sqz_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
sqz_M00926  Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:sqz00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    FQU76_19805
Enzymes [BR:sqz01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     FQU76_19805
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.75  uroporphyrinogen-III synthase
     FQU76_19805
SSDB
Motif
Pfam: HEM4 TP_methylase
Other DBs
NCBI-ProteinID: QDY78364
UniProt: A0A5B8JD94
LinkDB
Position
4543594..4545258
AA seq 554 aa
MSPTTNLSTAYDSAHGHVTFLGAGPGDPGLLTLRAVEALAGADVLIAEPDVLDVVRGHAR
ASVSTPELTVIDDASTAAGIPVLRDAVNLVMEAARSGRRVVRAVTGDPGLDADAGHEMLA
CAAEGIPFEVVPGIAAAVGVPAYAGVPLRDAQGADVRFVDARTASERCWSEVGASDGTVV
VSTTLDAVAAAAGELVAAGRKPDTPLTVTVAGTTTRQRTWAATLGTIAQVFKQGKVLPSP
EGHRPVIAVVGERSAPAQRDQLAWFESKPLFGWKVLVPRTREQAASLSDQLRSYGAVPHE
VPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKV
AAVGEQTAKALIDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATETL
VAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKPH
NVTVIACIGPATAKTAEEHGLRVDVLSPEPSVHRLAEALADFGAGRRAAAVEAGEHVTRP
SERRPGGRRRRTTT
NT seq 1665 nt   +upstreamnt  +downstreamnt
ttgagccccaccaccaacctgtccacggcgtacgactcggcacacgggcacgtcaccttc
ctcggcgccggtcccggcgatcccggactgctgaccctgcgggccgtcgaggccctcgcg
ggagccgacgtgctgatcgccgagcccgatgtgctcgacgtggtacgcggccacgcgcgg
gcgagcgtcagcacgcctgagctgacggtcattgacgatgcgtcaacagccgccggaatc
cccgtactcagggatgcggtcaatcttgtcatggaggccgcgcgctccggcaggcgggtc
gttcgagcggtgaccggcgatccggggctcgacgccgacgccggtcacgagatgctggcc
tgcgccgcggagggcattcccttcgaggtggtgcccggtatcgcggcggccgtgggcgtg
cccgcctatgccggggtgccgctgcgggacgcgcagggcgcggacgtccgtttcgtcgac
gcccggaccgcgagcgaacgctgctggtcggaggtgggggcgagcgacggcacggtcgtg
gtctcgaccacgctcgacgcggtcgccgccgcggcgggcgagctggtcgcggcgggccgc
aagccggacaccccgctgaccgtcaccgtcgccgggaccaccacccggcagcggacctgg
gccgcgacgctcggcacgatcgcgcaggtcttcaagcagggcaaggtgctgccgtccccg
gagggacaccggccggtgatagccgtggtcggtgagcgcagcgcgcccgcgcagcgcgat
cagctcgcatggttcgagtccaagccgctgttcggctggaaggtgctcgtcccgcggacg
agggagcaggcggcttccctgtcggaccagttgcgttcgtacggtgcggtgccgcacgag
gtgccgacgatcgcggtcgagccgccgcgtaccccgcagcagatggagcgggcggtcaag
ggcctggtcaccgggcggtacgagtggatcgccttcacctcggtgaacgcggtcaaggcg
gtccgggagaagttcgaggagtacgggctcgatgcccgcgccttcgccgggatcaaggtc
gcggcggtcggcgagcagaccgcgaaggcgctgatcgacttcggcgtcaagcccgatctg
gtgccgagcggcgagcagtcggccgccgggttgctggaggactggccgccgtacgacccg
gtcttcgacccgatcgaccgggtgttcctgccgcgggccgatatcgcgaccgagaccctg
gtcgcgggcctgatcgaactgggctgggaggtcgacgacgtcacggcctaccggaccgtg
cgggcctcgccgccgccggcggagacccgcgaggcgatcaagggcggtggcttcgacgcg
gtgctgttcacctcgtcgtcgaccgtacggaatctggtcgggatcgccgggaagccgcac
aatgtgacggtcatcgcgtgtatcggcccggcgacggcgaagaccgcggaggagcacggg
ctgcgggtggatgtgctgtccccggagccgtcggtgcaccggttggcggaggcgctggcc
gacttcggcgcggggcgccgggcggcggcggtcgaggcgggcgagcatgtcacccggccg
agtgagcggcgcccgggtggccgcagacggcgtacgacgacctga

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