Streptomyces rapamycinicus: M271_22465
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Entry
M271_22465 CDS
T02907
Name
(GenBank) uroporphyrin-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
src
Streptomyces rapamycinicus
Pathway
src00860
Porphyrin metabolism
src01100
Metabolic pathways
src01110
Biosynthesis of secondary metabolites
src01120
Microbial metabolism in diverse environments
src01240
Biosynthesis of cofactors
Module
src_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
src_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
src00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
M271_22465
Enzymes [BR:
src01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
M271_22465
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
M271_22465
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AGP56008
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All DBs
Position
complement(5634358..5636022)
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AA seq
554 aa
AA seq
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MNPTAPNHPGCGHVTFLGAGPGDPGLLTLRAVEALATADVLIADPQVLDVVRQHVRPGVA
AEAQGTPQPADADGSSGTATIPVLRDSANLVMTAARGGKRVVRAVAGDPGLDGYAADEML
ACAAEGIVFEVVPGVAAAVGVPAYAGVPLRDAHSADVRFVDALSADERCWSEIGSSDATA
VVSATLETVAAAAGELVAAGRKPDTPLTVTVAGTTTRQRTWTATLGTIAQVLKAAKVLPS
PQGAQPVIAVVGEQSAAGRRDQLSWFESKPLFGWKVLVPRTKEQAASLSDQLRGYGAVPS
EVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIK
VAAVGEQTARSLIDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATET
LVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKP
HNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVLKLAEALADFGAARRQAAIEAGEPVTR
PSERRPGSRRRARS
NT seq
1665 nt
NT seq
+upstream
nt +downstream
nt
ttgaaccccaccgccccgaatcaccccggctgcggacacgtcaccttcctcggtgcgggc
cccggagatccgggcctgctgaccttgcgcgccgtggaggcactcgccaccgcggacgtg
ttgatcgccgaccctcaagtgctcgacgtggtgcgccagcacgtcaggccgggcgtggcc
gcggaggctcagggcacgccgcagccggcggacgctgatgggtcgtcaggcaccgccacc
atcccggtactcagggacagcgccaatcttgtcatgacggccgcgcgcggcggcaagcgg
gtcgtgcgcgcggtcgcgggcgaccccggcctcgacggatacgccgccgacgagatgctc
gcctgcgcggccgagggcatcgtcttcgaggtggtgcccggtgtggccgccgcggtgggc
gtgcccgcctacgcgggggtgccgctgcgggacgcccacagcgcggatgtgcgcttcgtg
gacgccctgagcgccgacgagcgctgctggagcgagatcggctcgtccgacgcgaccgcc
gtggtctccgcgacgctggagacggtggccgccgcggcgggtgagctggtggccgcgggc
cgcaagccggacaccccgctcaccgtcaccgtcgcgggcaccaccacccgccagcggacc
tggaccgcgacgctggggaccatcgcccaggtgctgaaggcggcgaaggtgctgccgtca
ccgcagggcgcccagccggtgatagccgtggtcggcgagcagagcgcggccggccggcgc
gatcagctgtcatggttcgagtccaagccgctgttcggctggaaggtcctggtgccgcgc
accaaggagcaggccgcctcgctctcggatcagctgcgcggctacggcgcggtgcccagt
gaggtgccgaccatcgccgtggagccgccgcgcaccccgcagcagatggagcgcgcggtc
aagggcctggtcaccgggcgctatgagtggatcgccttcacctcggtcaacgcggtcaag
gcggtgcgggagaagttcgaggagtacgggctcgacgcccgcgcgttcgccgggatcaag
gtcgcggcggtgggcgagcagaccgcgaggtcgctgatcgacttcggggtgaagccggat
ctggtgcccagcggtgagcagtccgcggccgggctgctggaggactggccgccgtacgac
ccggtgttcgacccgatcgaccgggtgttcctgccgcgtgccgacatcgccaccgagacc
ctggtcgccgggctgatcgagctgggctgggaggtcgacgacgtgaccgcgtaccgcacc
gtgcgcgcctcgccgccgccggccgagacccgggaggccatcaagggcggcgggttcgac
gcggtgctcttcacctcgtcgtccaccgtgcggaacctcgtcggcatcgcgggcaagccg
cacaatgtcactgtcatcgcctgtatcggcccggccaccgcgaagaccgcggaggagcac
ggactgcgggtggatgtgctgtcgcccgagccctcggtgctcaagctggccgaggcgctc
gcggacttcggggcggcgcggcggcaggccgcgatcgaggccggggagccggtcacccgc
ccgagcgagcgacggcctggttcgcgaaggagggcacgctcttga
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