Streptomyces rochei: SRO_3255
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Entry
SRO_3255 CDS
T06265
Name
(GenBank) uroporphyrin-III methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
srj
Streptomyces rochei
Pathway
srj00860
Porphyrin metabolism
srj01100
Metabolic pathways
srj01110
Biosynthesis of secondary metabolites
srj01120
Microbial metabolism in diverse environments
srj01240
Biosynthesis of cofactors
Module
srj_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
srj_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
srj_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
srj00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
SRO_3255
Enzymes [BR:
srj01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
SRO_3255
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
SRO_3255
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Motif
Pfam:
HEM4
TP_methylase
RodZ_C
Motif
Other DBs
NCBI-ProteinID:
BBC94431
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Position
complement(3622241..3623944)
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AA seq
567 aa
AA seq
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MSPTALPAAGPEHGHVTFLGAGPGDPGLLTLRAVEALSNADVLIAEPEVLDVIRTHARQG
VSVVHTDGNLSTSPPGTPQLTVVDGTSTTAAAPSPARDAAHLVMEAARGGRRVVRAVSGD
PGLDTDAAEEMLACAAAGVPFEVVPGVAAAVGVPAYAGVPLRDADGADVRFVDARTASDR
CWTEVGASDGTVVVSTTLDAVAAAAGELVSAGRKPDTPLTVTVAGTTTRQRTWSATLGTI
AQTLKQAKVLPSPDGGRPVIAVVGERSAAARRDQLSWFESKPLFGWKVLVPRTKEQSAAL
SEQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEE
YGLDARAFAGIKVAAVGEQTARALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDR
VFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSS
TVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVAKLAEALADFGAKRR
DAALESGDPVTRPSERRPGARRRRSTT
NT seq
1704 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccgcccttcctgccgccggtccggaacacgggcacgtcaccttcctcggt
gccggacccggggatccgggactgctgactctgcgcgccgtggaggcactgtcgaacgcg
gacgtcctgatcgccgagcccgaggtgctcgatgtgatccggacgcacgcgcggcagggc
gtctccgtcgtgcacaccgacgggaacctctccacgtcgccaccgggcacgccgcagctc
acggtcgttgacggcacgtcaaccaccgccgctgccccgtctcctgcccgggatgccgct
catcttgtcatggaggccgcgcggggcggcaggcgggtcgtgcgtgcggtctcgggtgac
cccgggctcgacacggacgccgccgaggagatgctggcgtgcgccgcggccggggtgccc
ttcgaggtggtacccggtgtcgccgccgcggtgggtgtgccggcgtacgccggtgtgccg
ctgcgggacgcggacggcgcggacgtccggttcgtggacgcccgtaccgcctcggaccgc
tgctggaccgaggtcggcgcctccgacggcacggtggtcgtctccacgaccctggacgcg
gtggccgccgcggcgggcgagctggtctcggccggccgcaagccggacaccccgctgacg
gtcaccgtcgccggtacgacgacgcgccagcgcacctggtccgcgacgctcggcaccatc
gcgcagacgctgaagcaggcgaaggtgctgccctcgccggacggtggccgcccggtgata
gcggtggtcggcgagcgttccgccgccgcccggcgcgaccagctctcatggttcgagtcc
aagccgctgttcggctggaaggtgctcgtgccgcgcacgaaggaacagtcggcggcgctc
tccgagcagctgcggtcctacggcgcggtgccgcacgaggtccccaccatcgcggtggag
ccgccgcgcacgccccagcagatggagcgcgcggtcaagggcctggtcaccggccgctac
gagtggatcgccttcacgtcggtcaacgcggtgaaggcggtgcgggagaagttcgaggag
tacggccttgacgctcgggcttttgcgggtatcaaggtggctgcggtgggcgagcagacg
gctcgcgcgctgatcgccttcggcgtgaagccggacctggtcccgagcggcgagcagtcg
gccgccggtctgctggaggactggcccccctacgacccggtcttcgacccgatcgaccgt
gtcttcctcccgcgcgcggacatcgccacggagaccctggtggccggtctgatcgagctg
ggctgggaggtcgacgacgtcacggcctaccgcaccgtgcgcgcctcgcccccgccggcc
gagacccgcgaggcgatcaagggcggcggcttcgacgcggtcctgttcacctcgtcctcc
acggtccgcaacctggtcggcatcgcgggcaagccgcacaacgtgacggtgatcgcctgc
atcggccccgcgacggcgaagacggccgaggaacacggcctccgcgtcgacgtcatggcc
ccggaaccctcggtcgcgaaactggccgaggccctggccgacttcggcgcgaagcgccgc
gacgcggcgctggagtcgggcgacccggtgacccgcccgagcgagcgccgaccgggggcg
cggaggcgtcgttcgacgacctga
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