Streptomyces rectiverticillatus: FGW37_14860
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Entry
FGW37_14860 CDS
T06927
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
srk
Streptomyces rectiverticillatus
Pathway
srk00860
Porphyrin metabolism
srk01100
Metabolic pathways
srk01110
Biosynthesis of secondary metabolites
srk01120
Microbial metabolism in diverse environments
srk01240
Biosynthesis of cofactors
Module
srk_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
srk_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
srk00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
FGW37_14860
Enzymes [BR:
srk01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
FGW37_14860
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
FGW37_14860
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QLE72713
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Position
complement(3413347..3414996)
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AA seq
549 aa
AA seq
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MNPTAPNHPVHGHVTFLGAGPGDPGLLTLRAVEALAAADVLIADPQVLDVVRTHARAHVD
MPAQTVTDEASKTADVPVLRDTANLVMTAARSGKRVVRAVHGDPGLDGDAADEMLACAAE
GITFEVVPGVATAVGVPAYAGVPLRDGKGGDVRFVDARTASATCWSEVGASEVTAVVSTT
LDSVVSAAGELVSAGRGPDTPMTVTVAGTTTRQRTWTATLGTLAQVLKAAKVLPSADGAQ
PVIAVVGERSAAEQRDRLSWFESKPLFGWNVLVPRTKEQSASLSDQLRSYGAVPSEVPTI
AVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKVAAVG
EQTAKSLIEFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATETLVAGL
IELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHNVTV
IACIGPATAKTAEEHGLRVDVLSPEPSVLKLAEALAEFGAARRDAALEAGDPVTRPSERR
PGSRRRARS
NT seq
1650 nt
NT seq
+upstream
nt +downstream
nt
ttgaaccccaccgccccgaaccaccccgtgcacgggcacgtcaccttcctcggtgccggc
cccggagacccgggactgctgacgctccgcgccgtggaggcgcttgcggccgcggacgtc
ctgatcgccgatccgcaggtgctcgacgtggtgcgcacgcatgcgcgcgcccatgtggac
atgcctgcccagacggttactgacgaggcatcaaaaaccgcggacgtccccgtccttagg
gacaccgccaatcttgtcatgacggccgcgcgcagcggcaagcgggtcgtccgtgccgtg
cacggcgaccccggcctcgacggcgacgccgccgacgagatgctcgcctgcgccgccgag
ggcatcaccttcgaggtggtccccggcgtcgccacggccgtcggcgtgcccgcctacgcc
ggtgtgccgctgcgtgacggcaagggcggcgacgtgcgcttcgtcgacgcccgcacggcc
tcggccacctgctggtccgaggtaggcgccagcgaggtcaccgccgtcgtctccaccacg
ctcgactccgtcgtctccgccgccggcgaactggtctccgccggccgcggccccgacacg
ccgatgaccgtcacggtcgccggcaccaccacccgccagcgcacctggaccgccaccctc
ggcaccctggcccaggtgctcaaggccgcgaaggtgctgccgtccgccgacggcgcccag
ccggtcatagccgtggtcggcgagcgcagcgctgccgagcagcgcgaccggctctcctgg
ttcgagtccaagccgctcttcggctggaacgtcctcgtgccgcgcaccaaggagcagtcc
gcctcgctctccgaccagctccgttcctacggcgccgtgcccagcgaggtcccgaccatc
gccgtcgagccgccgcgcaccccccagcagatggagcgcgcggtcaagggcctggtcacc
ggccgctacgagtggatcgccttcacctccgtgaacgccgtcaaggcggtgcgcgagaag
ttcgaggagtacgggctcgacgcgcgtgccttcgccggcatcaaggtcgcggccgtcggc
gagcagaccgccaagtcgctgatcgagttcggcgtcaagcccgacctcgtgccgtccggc
gagcagtccgccgccggcctgctggaggactggccgccctacgaccccgtcttcgacccg
atcgaccgcgtcttcctgccgcgcgccgacatcgccaccgagaccctggtggccggcctg
atcgagctgggctgggaggtcgacgacgtcaccgcctaccgcaccgtccgggcctcgccg
ccgccggccgagacccgcgaggccatcaagggcggcggtttcgacgccgtgctcttcacc
tcctcgagcacggtgcgcaacctcgtcggcatcgccggcaagccccacaatgtcaccgtc
atcgcctgtatcggcccggccaccgcgaagaccgcggaggaacacggcctgcgggtggac
gtgctgtctcccgagccttcggtgctcaagctcgccgaggcgctcgcggagttcggcgcg
gcccgccgggacgccgccctggaggccggcgacccggtcacccgcccgagcgagcgacgg
cccggatcgcgtagaagggcacggagttga
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