Streptomyces rubrolavendulae: A4G23_03174
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Entry
A4G23_03174 CDS
T04616
Symbol
nasF_2
Name
(GenBank) Uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
srn
Streptomyces rubrolavendulae
Pathway
srn00860
Porphyrin metabolism
srn01100
Metabolic pathways
srn01110
Biosynthesis of secondary metabolites
srn01120
Microbial metabolism in diverse environments
srn01240
Biosynthesis of cofactors
Module
srn_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
srn_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
srn_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
srn00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
A4G23_03174 (nasF_2)
Enzymes [BR:
srn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
A4G23_03174 (nasF_2)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
A4G23_03174 (nasF_2)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AOT60303
UniProt:
A0A1D8G4F5
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Position
3688150..3689817
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AA seq
555 aa
AA seq
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MSPTTASKASSAFSACGHVTFLGAGPGDPGLLTLRAVEALAGADVLIAEPEVLDVVRGHA
RAGVSTPELTVVDDASMAAGVPVLRDAANLVMEAARGGKRVVRALSGDPGLDGDAGAEML
ACASAGIPFEVVPGVAAAVGVPAYAGVPLRDAQGADVRFVDARTASDRCWTEVGASDGTV
VVSTTLDSVAAAAGELVAAGRKPDTPLTVTIAGTTTRQRTWTATLGSIAQTLKQAKVLPS
PEGHRPVIAVVGERSAAAQRDQLAWFESKPLFGWKVLVPRTKEQAASLSDQLRSYGAVPS
EVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIK
VAAVGEQTAKALVDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATET
LVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKP
HNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVTKLAEALAEFGAKRRAAALEAGDPVTR
PSERRPGARRRRTTT
NT seq
1668 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccactgcatccaaggcttcctcggcgttctccgcgtgcgggcacgtcacc
ttcctcggcgccggacccggtgatccggggctgctgactctgcgcgccgtggaggcgctg
gcgggcgctgacgtactgatcgccgagcccgaagtgctcgacgtcgtacgcggccatgcc
cgagcgggggtgagcacgcccgagctgacggttgttgacgatgcgtcaatggccgccggg
gtcccggtgttgagggacgccgccaatcttgtcatggaggccgcgcggggcggcaagcgg
gtggtgcgtgcgctcagcggcgacccgggcctcgacggcgacgcgggcgccgagatgctc
gcctgcgcgtccgccggcatccccttcgaggtggtgcccggtgtcgccgcggcggtcggc
gtgcccgcgtacgccggtgtcccgctgcgggacgcgcagggcgcggacgtgcggttcgtg
gacgcccgtacggccagcgaccggtgctggacggaggtcggcgcgtccgacggcacggtc
gtcgtgtccacgacgctggactcggtcgccgctgccgccggtgagctggtcgcggccggg
cggaagccggacaccccgctgaccgtcaccatcgccggtacgacgacccggcagcggacg
tggaccgccacgctcggctcgatcgcccagacgctgaagcaggcgaaggtgctgccctcc
ccggagggccaccggcccgtcatagccgtggtcggtgagcgcagcgccgccgcccagcgc
gaccagctcgcgtggttcgagtccaagccgctgttcggctggaaggtcctcgtcccgcgc
accaaggagcaggcggcgtcgctctccgaccagctcaggtcgtacggggcggtgcccagc
gaggtcccgaccatcgcggtcgagccgccgcgcaccccgcagcagatggagcgggcggtc
aagggcctggtcaccggccgctacgagtggatcgccttcacctcggtcaacgccgtgaag
gccgtccgcgagaagttcgaggagtacgggctcgacgcccgcgccttcgccgggatcaag
gtcgcggcggtcggcgagcagaccgcgaaggccctggtcgacttcggcgtcaagccggac
ctggtgcccagcggcgagcagtccgcggccgggctcctggaggactggccgccgtacgac
ccggtcttcgacccgatcgaccgggtgttcctgccgcgcgccgacatcgccaccgagacg
ctggtggccgggctcatcgagctgggctgggaggtggacgacgtcacggcctaccggacc
gtgcgcgcgtcgccgcccccggcggagacccgcgaggcgatcaagggcggcggcttcgac
gcggtgctgttcacgtcgtcgtcgaccgtgcggaacctggtcggcatcgcgggcaagccg
cacaacgtcacggtgatcgcctgcatcggcccggccaccgccaagacggcggaggagcac
ggcctgcgcgtggacgtgctgtcgccggagccgtcggtgacgaagctggcggaggccctg
gcggagttcggcgcgaagcgccgcgccgccgcgctggaggcgggtgacccggtcacccgt
ccctccgagcggcgccccggcgcccgccgccgccgcacgacgacctga
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