Streptosporangium roseum: Sros_0550
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Entry
Sros_0550 CDS
T01137
Name
(GenBank) uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sro
Streptosporangium roseum
Pathway
sro00860
Porphyrin metabolism
sro01100
Metabolic pathways
sro01110
Biosynthesis of secondary metabolites
sro01120
Microbial metabolism in diverse environments
sro01240
Biosynthesis of cofactors
Module
sro_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
sro_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sro_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sro00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Sros_0550
Enzymes [BR:
sro01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Sros_0550
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Sros_0550
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
ACZ83574
UniProt:
D2B2U7
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Position
555719..557299
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AA seq
526 aa
AA seq
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MSSGSTTFERPAGFVAFVGAGPGDEGLLTLRGADLLSKADVVVLDQEAYGTLLRHCREGV
EVVEAADEDAVSLRTVTAAKGGRVVVRLCAGDPMFFSSITEEVAACAKAEVDFEIVPGVP
PATAVLTYAGIPAAVAVPEFRVVDATQVDDWSAHATGAGTLVIYNGVSGAVAIGKALIAA
GRPDSTPVAISSAGTTTEQYTVVTTLGRIAPDLKHAGMTEPALIVVGEAVGMRDQLSWFE
TKPLFGWRVLVPRTKEQSAGLVEQLRSYGAVPEEVPTISVEPPRTPQQMDRAIKGLVTGR
YEWVAFTSSNAVKAVREKFEEYGLDARAFAGLKVAAVGEATARALVQFGVKPDLMPSGEQ
SSDGLLAEWPPYDSMLDPINRVLLPRADIATETLVAGLTELGWECDDVTAYRTVRAAPPP
APIREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHNVTVIAVIGPQTAKTAEEFGLRVDVM
ADRPSASALAAALAEYGAKQRQAALAAGDVPRRPSQTRRGARRRAK
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
ttgagctccggaagtaccaccttcgagcgcccggccgggttcgtcgccttcgtgggggcg
ggccccggtgacgagggcctgctcacgctccgtggcgccgacctgctctcgaaggccgac
gtcgtcgtgctcgaccaggaggcgtacggcacgctgctgcgccactgccgggagggcgtc
gaggtcgtcgaagccgccgacgaggacgcggtctcgctgagaaccgtcacagcggccaag
ggcgggcgcgtcgtcgtgcggctctgcgccggcgacccgatgttcttctcctcgatcacc
gaggaggtcgcggcctgcgccaaggcggaggtggacttcgagatcgtgccgggcgtgccc
ccggcgacggcggtgctcacctacgcgggcatccccgccgcggtggcggtgccggagttc
cgggtcgtggacgcgacccaggtcgacgactggagcgcccacgccacgggcgccggcacc
ctggtgatctacaacggcgtctccggggccgtcgcgatcggcaaggcgctgatcgccgcg
ggccggccggactcgacgccggtcgcgatcagcagcgcgggcaccaccaccgagcagtac
accgtggtgaccacgctcggccggatcgcgcccgacctcaagcacgccgggatgaccgag
cccgcgctgatcgtggtcggcgaggccgtcggcatgcgtgaccagctgtcgtggttcgag
accaagccgctgttcggctggcgggtgctcgtacccaggaccaaggagcagtcggccggc
ctggtggagcagctgcgctcctacggcgcggtgccggaggaggtccccacgatctccgtc
gagccgccgcgcaccccgcagcagatggaccgggcgatcaagggcctggtcaccggccgc
tacgagtgggtggcgttcaccagctcgaacgcggtcaaggccgtgcgcgagaagttcgag
gagtacggcctggacgcccgcgcgttcgccgggctcaaggtcgcggccgtcggcgaggcc
accgcgcgggcgctggtgcagttcggcgtcaagccggacctcatgccgtcgggcgagcag
tcgtcggacggcctgctggccgagtggccgccgtacgactcgatgctcgacccgatcaac
cgggtgctgctgccccgggccgacatcgcgaccgagacgctggtcgcggggctgaccgag
ctcggctgggagtgcgacgacgtgaccgcctaccggaccgtccgcgcggcgccgccgccc
gcgccgatccgggaggccatcaagggcggcgggttcgacgcggtgctgttcacctcgtcg
agcaccgtgcgcaacctggtgggcatcgcgggcaagccgcacaacgtcacggtcatcgcc
gtgatcggcccgcagaccgccaagaccgccgaggagttcgggctccgcgtcgacgtgatg
gccgacaggccgtcggcttcggccctcgcggcggcgctggccgagtacggcgccaagcag
cggcaggccgcgctcgcggccggagacgtcccgcgcaggccctcccagacccggagaggt
gcccggcgccgcgccaagtaa
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