Streptomyces roseirectus: IAG44_17005
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Entry
IAG44_17005 CDS
T07860
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sroi
Streptomyces roseirectus
Pathway
sroi00860
Porphyrin metabolism
sroi01100
Metabolic pathways
sroi01110
Biosynthesis of secondary metabolites
sroi01120
Microbial metabolism in diverse environments
sroi01240
Biosynthesis of cofactors
Module
sroi_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
sroi_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sroi_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sroi00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
IAG44_17005
Enzymes [BR:
sroi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
IAG44_17005
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
IAG44_17005
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Motif
Pfam:
HEM4
TP_methylase
RodZ_C
Motif
Other DBs
NCBI-ProteinID:
QNP70966
UniProt:
A0A7H0IDV0
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Position
complement(4105572..4107257)
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AA seq
561 aa
AA seq
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MSPTTLPSGLDHGHVTFLGAGPGDPGLLTLRAVEALANADVLVAEHEVLDVVRTHARTGV
SVVPTDPAPGTIAPQPTVVDSASTTVALPVMRDAAHLVMEAARGGRRVVRAVSGDPGLDT
YAAAEMLACASAGVPFEVVPGVAAAVGVPAYAGVPLRDAQGADVRFVDARTASDRCWTEV
GASDGTVVVSTTLDAVAAAAGELVSAGRKPDTPLTVTVAGTTTRQRTWCATLGTIAQMLK
QAKVLPSPDGGRPVIAVVGERSAPAQRDQLAWFESKPLFGWKVLVPRTKEQAASLSEQLR
SYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDA
RAFAGIKVAAVGEQTAKALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPR
ADIATETLVAGLIDLGWEVDDVTAYRTVRASPPPADTREAIKGGGFDAVLFTSSSTVRNL
VGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSAQKLAEALAEFGMRRRAAALE
AGDAVTRPSERRPGGRRRRAT
NT seq
1686 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccacccttccctccggcctggaccacgggcacgtcacctttctgggtgcc
ggacccggggatccgggactgctgactctgcgcgccgtggaggcgctggcgaacgcggac
gtcctcgtcgccgagcacgaggtgctcgacgtcgtccggacgcacgcgcggaccggcgtc
tccgtcgtgcccacggaccccgccccgggcacgatcgcaccacagcccacggtagttgac
agtgcgtcaacgaccgtcgcgcttcccgtgatgcgggatgcggcacatcttgtcatggag
gccgcgcggggcggcaggcgggtcgtgcgtgcggtctccggtgatccgggacttgatacg
tacgccgccgccgaaatgctcgcctgcgcctccgccggggtgcccttcgaggtcgtgccc
ggtgtcgccgccgccgtcggcgtcccggcctacgccggggtgcccctgcgcgacgcgcag
ggggcggacgtccggttcgtggacgcccgtaccgcctccgaccggtgctggacggaggtg
ggggcgtccgacgggaccgtggtcgtgtcgacgaccctcgacgccgtcgccgcggccgcc
ggggagctggtgtccgccgggcgcaagccggacaccccgctgaccgtgaccgtcgccggg
acgacgacccggcagcggacctggtgcgcgaccctcgggaccatcgcgcagatgctgaag
caggccaaggtgctgccctcgccggacggcgggcggccggtgatagccgtcgtcggtgag
cggtcggcgccggcgcagcgggatcagctggcctggttcgagtcgaagccgctcttcggg
tggaaggtgctggtgccccggacgaaggagcaggccgcttcgctgtccgagcagctgcgg
tcctacggggccgtgccgcacgaggtgcccaccatcgccgtcgagccccctcgtacgccg
cagcagatggagcgggccgtcaaggggctcgtcaccgggcggtacgagtggatcgccttc
acctcggtcaacgcggtcaaggcggtgcgggagaagttcgaggagtacgggctcgacgcg
cgcgccttcgccgggatcaaggtcgcggcggtgggggagcagaccgccaaggcgctgatc
gccttcggcgtgaagccggatctcgtgcccagcggggagcagtccgccgccgggctgctg
gaggactggcctccctacgaccccgtcttcgatccgatcgaccgggtgttcctgcctcgg
gccgatatcgccacggagacgctggtcgccgggctcatcgatctcgggtgggaggtggac
gatgtcaccgcgtaccggacggttcgggcgtcgccgccgcctgccgatactcgggaggcg
atcaaggggggtgggttcgatgccgtgctgttcacgtcgtcgtccaccgtgcggaacctt
gtcgggatcgccgggaagccgcacaacgtgaccgtcatcgcctgtatcgggccggctacc
gccaagaccgccgaggagcatgggcttcgggtggatgtgatggctcctgagccgtccgcg
cagaagttggccgaggcgttggccgagttcgggatgcggcggagggctgccgcgctggag
gcgggggacgcggttactcggccgagtgagcggaggccggggggacggcggcggcgggcc
acctga
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