Streptomyces rutgersensis: F0345_11645
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Entry
F0345_11645 CDS
T08623
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
srug
Streptomyces rutgersensis
Pathway
srug00860
Porphyrin metabolism
srug01100
Metabolic pathways
srug01110
Biosynthesis of secondary metabolites
srug01120
Microbial metabolism in diverse environments
srug01240
Biosynthesis of cofactors
Module
srug_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
srug_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
srug00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
F0345_11645
Enzymes [BR:
srug01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
F0345_11645
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
F0345_11645
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QNE81692
UniProt:
A0A7G7C276
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All DBs
Position
complement(2777592..2779256)
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AA seq
554 aa
AA seq
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MSPTTAVNSMFSDHGHVTFLGAGPGDPGLLTLRAVEALAAADVLVAEERVLDVVRAHARA
GADMPQLSTDEASTPVETRRIGDAANLVMGAARAGKRVVRAVQGDPGLDSEAVREMLACA
AEGVTFEVVPGIAEAVGVPAYAGVPLRDEAGADVRFVDARTATDRCWTELGASDGTVVVS
TSLDQAAATAGELVAAGRKPDTPMTLTVAGTTTRQRTWDATLGTVAQVLKQAKVLPSPEG
GRPVIAVVGEHCAPARRDQLSWFESKPLFGWKVLVPRTKEQAASLSDQLRSYGAVPHEVP
TIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKVAA
VGEQTADALIAFGVKPDLVPSGEQSAAGLLDDWPPYDPVFDPIDRVFLPRADIATETLVA
GLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVMFTSSSTVRNLVGIAGKPHNV
TVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALAAFGAERRMAALEAGESVARPSE
RRPGARRRRAASSS
NT seq
1665 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccaccgctgtaaattcaatgttctccgaccatgggcacgtcaccttcctg
ggtgccggtcccggcgacccggggcttctcactctgcgtgccgtcgaggcgctggccgcg
gccgacgtcctggtcgcggaggagcgggtgctcgacgtcgtcagggcgcacgccagggcg
ggcgcggacatgccgcagctgtccactgacgaggcgtcaacccccgtggagacccgccga
atcggcgacgccgccaatcttgtcatgggggccgcgcgcgccggaaagcgggtcgtgcgc
gccgtccagggcgacccggggctcgactccgaggccgtccgcgagatgctcgcctgcgcc
gccgagggcgtcaccttcgaggtggtcccgggcatcgcggaggcggtcggcgtacccgcg
tacgccggtgtcccgctgcgcgacgaggccggcgccgacgtgcgcttcgtcgacgcccgc
accgccaccgaccgctgctggaccgagttgggcgcgagcgacggcaccgtcgtcgtctcc
accagcctcgaccaggccgcggccaccgcgggcgaactggtggcggccgggcgcaagccc
gacaccccgatgacgctcaccgtcgccgggaccaccacccgccagcggacctgggacgcc
acgctcggcaccgtcgcgcaggtcctcaagcaggccaaggtgctgccctcgccggaaggc
ggccgtccggtcatagccgtggtcggtgagcactgtgccccggcccgccgcgaccagctc
tcctggttcgagtcgaagccgctgttcggctggaaggtcctggtgccgcgcaccaaggag
caggcggcctcgctctccgaccagctccgttcctacggcgcggtgccgcacgaggtgccg
accatcgccgtggagccgccgcgcaccccgcagcagatggagcgggccgtcaagggcctg
gtcaccggacgctacgagtggatcgccttcaccagcgtcaacgccgtcaaggcggtccgg
gagaagttcgaggagtacgggctcgacgcgcgggccttcgcgggcatcaaggtcgccgcc
gtcggcgagcagaccgcggacgcgctgatcgccttcggcgtcaagcccgacctcgtcccc
tcgggcgagcagtccgcggccgggctcctggacgactggccgccgtacgacccggtcttc
gacccgatcgaccgggtgttcctgccgcgcgccgacatcgccaccgagaccctggtggcc
gggctgatcgagctgggctgggaggtggacgacgtcaccgcctaccggacggtgcgcgcc
tcgccgccgccggccgagacccgcgaggcgatcaagggcggcggcttcgacgcggtcatg
ttcacctcgtcctcgaccgtccgcaacctggtcggcatcgccggcaagccgcacaacgtc
acggtcatcgcctgtatcgggcccgccaccgccaagacggcggaggagcacggcctgaga
gtggacgtgatggcgcccgagccctccgtgcacaagctggccgaggcactggccgccttc
ggcgcggagcgccggatggccgcgctggaggccggggagagcgtcgcgaggcccagcgag
cggcgccccggcgcccggcgccgcagggccgcctcctcctcgtga
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