Sus scrofa (pig): 100157745
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Entry
100157745 CDS
T01009
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
ssc
Sus scrofa (pig)
Pathway
ssc00562
Inositol phosphate metabolism
ssc01100
Metabolic pathways
ssc04014
Ras signaling pathway
ssc04015
Rap1 signaling pathway
ssc04020
Calcium signaling pathway
ssc04024
cAMP signaling pathway
ssc04070
Phosphatidylinositol signaling system
ssc04919
Thyroid hormone signaling pathway
ssc04933
AGE-RAGE signaling pathway in diabetic complications
ssc05205
Proteoglycans in cancer
Module
ssc_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
ssc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
100157745 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100157745 (PLCE1)
04015 Rap1 signaling pathway
100157745 (PLCE1)
04020 Calcium signaling pathway
100157745 (PLCE1)
04070 Phosphatidylinositol signaling system
100157745 (PLCE1)
04024 cAMP signaling pathway
100157745 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100157745 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100157745 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100157745 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ssc04131
]
100157745 (PLCE1)
Enzymes [BR:
ssc01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
100157745 (PLCE1)
Membrane trafficking [BR:
ssc04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
100157745 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
100157745 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
100157745
NCBI-ProteinID:
XP_020929664
LinkDB
All DBs
Position
14:105422628..105764736
Genome browser
AA seq
2316 aa
AA seq
DB search
MTSEEMAASVLLPVTQRKVVSAQLAVDESSEKGTDINFPKSLPIRQCGETSHTISQLNTL
TEESSGSNLHTNLSAAKETIMSDENSNEKCWERSMPDSVKNLNINCNNILKNHQRGLPQS
QFYETCESITEEDLCLETGIPSPLERKVFPGIQLEMDRPPMGMGPLGTQSAIIEMGRAHP
DSNPTVIHFRYEVDRRMPDTFCPLSDNLVLDDCGNCVLPGVGGEPKKNYLAYTCKLMELA
NNCDNKNRQLQYDPCDPLNDKSLCFEASFPKANVLCSRDSFCREDFTDNPPAKTFLSHFE
DFPDNCEDVEEDFLKSKRERSTWLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLGAW
SYIDQKRNGLSLPFRRVMGRLSTVVIRQDGRQCLSEAHWYPIYSAVRRGEETEETIGSLL
HFFTKPSASETAHERISIGPCLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGAR
SSLLSSFGGSTGRMMLKERQPGISMANSSALPSSSAGISKELIDLQPLIQFPEEVASILM
EQEQTIYRRVLPVDYLCFLTRDLGTPECQRSLPCLKASISASILTSQNGEHNALEDLVMR
FNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMW
QFMDQSDLETMRSLKDAMAQHESSCEYKKVVTRALHIPGCKVVPFCGVFLKELCEVLDGA
SGLMKLCPRYNSQEEALEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSRS
LEIEEEDSPSEGSSSRKNSLKDKARWQFIIGDLLDSENDIFEQPKDWDPHGSEEPQKAFD
HGTELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWIKPTTAS
LASAKAKLGVLSNTSEPGKFPLLGNAGLSGLVEGVLDLFSAKAVYMGHPNIDIHTVCVQN
KLSNMSLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQ
QWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPNMQRNNTLG
ISTTKKKKKILMRGESGEATDDEMAMRKAKTHKECRSRSGSDPQDINEQEESEANTITSP
PNPLPSRRAHSLTTAGSPNVAAGTSSPIRPVSSPVLSSSNKSPSSAWSSSSWHGRIKGGM
KGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDIYAVPCDRAGSEPAPLYTNLTI
DENTSGLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLG
VFGIGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSVSMCHQGLMSFEGFARFLMDKDNF
ASKNDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDC
WDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFITSDLPIIISIENHCSLPQQRKMAEI
FKTVFGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLA
SMQAQAYNGGSANPPPANNEEEEDEEDEYDYDYESLSDADVLTASPAPNSQEDNILEDRP
ENKSCNDKLQFEYNEEIPKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELS
DLVIYCQAVKFPGLSTLNASGSSRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSCE
GMRQAWEDSSSSVNPTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLR
TYPAATRIDSSNPNPLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLW
DKNCPMYQKFSPLERDLDSMEPAIYSLTIVSGQNVCPSNSTGSPCIEVDVLGMALDSCHF
RTKPIHRNTLNPMWNEQFLFRVHFEDLLFLRFAVVENNSSAVTAQRIIPLKALKRGYRHL
QLRNLHNEVLEISSLFINSRRMEENSSGSPMPASLMFNTEERKCLQTHRVTVHGVPGPEP
FTVFSINGGTKAKQLLQQILTIDQDTKPIATDYFLMEEKYFISKEKNECRKQPFQRAIGP
EEEIMQILSSWFPEEGYVGRIVLKTQQENLEEKSIVQDDKEMILSSEEESFFVQVHDVSP
EQPRTVIKAPRVSTAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKSSTPK
SSQRVLLDQECVFQAQSKWKGAGKFILKLKEQVQASREDKRKGISFASELKKLTKSTKQP
RGLTSPAPVLASESVQNKEEKPAGGLSSSDTVDYRQ
NT seq
6951 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaatggcagcttctgttctcttacctgtgactcagagaaaagtggta
tctgctcagttggctgtagatgaaagtagtgaaaagggcacagacatcaattttccaaag
tcccttcccatcaggcagtgtggagagacttctcataccatctcacaactgaacacactt
acagaagaatcttctggaagcaacttgcacacgaatctctcagcagcaaaggagacaata
atgagtgatgagaacagtaatgaaaagtgctgggagagaagcatgccagattctgtgaaa
aaccttaatattaactgcaacaacatattgaaaaatcatcagcgtggccttcctcagagc
cagttttatgaaacatgcgagtctatcacagaggaagacctgtgtttagaaactggaatc
ccttctccactggaaagaaaggtgttccctggaattcaactggaaatggacagacctccc
atgggcatgggtccattaggaactcaatcagccatcatagagatgggccgggcacaccct
gacagcaacccgacagtgattcactttcgttatgaagtggacagaagaatgccagacact
ttctgtcccctgtcagataacttggtcttggatgattgtggaaactgtgtactgcctggt
gttggtggggagccaaagaaaaattacttggcgtatacttgcaaactgatggaattggca
aataactgtgataataagaataggcagctgcagtatgatccttgtgaccctttgaatgac
aaatccttgtgctttgaagcctctttcccaaaggccaatgtgctatgttcaagggacagc
ttttgcagggaggattttactgacaatccacctgccaagacctttctgagccattttgag
gacttccctgataattgtgaagatgtagaagaagattttctcaaaagcaaaagggagcgg
tccacttggttagtgaggagattttgtaaaaacgacagagaagttaagaaatcggtgtat
accgggaccagggccattgtgagaactctgccttctggtcacattgggctgggagcttgg
agttacattgatcagaagagaaatggtctctcactgcctttcaggagagtcatgggacgg
ctgtcaacagtggtgatcaggcaagatgggcgccagtgtctgtcagaagcccactggtat
ccgatctacagtgcagtgagaaggggagaagaaacagaagagacaattggatccctcctc
cacttcttcacaaagccctcagcctctgagacagcccatgaaaggattagcatcggtccg
tgcttaaagcaatgtgttcgagacactgtttgtgaatatcgtgccaccctgcaaaggact
tccatatctcagtatatcactggctccctcttagaagccaccacatctctaggagcaaga
agtagccttctcagttcttttggaggatccactggacgaatgatgctgaaagaacgccaa
ccaggcatctctatggccaattccagtgcccttccttcaagttcagctgggatcagcaag
gaactgattgatctgcagcccctcatccagttcccagaggaagttgccagcatcctgatg
gagcaggagcaaaccatttaccgaagggtcttgccggttgactatctttgcttcttgacc
cgggacttgggcactccagaatgccagaggtcgttgccctgcctcaaagcatccatctca
gcatccattcttacctcccagaatggagagcataatgcccttgaagatcttgtgatgaga
tttaatgaggtgagctcctgggtgacgtggctgatcctcactgcaggctccatggaggag
aagcgggaagtcttctcgtacttggtgcatgtggccaaatgctgctggaacatgggcaac
tacaacgccgtcatggagttcttggccggcctcaggtcaagaaaagttttaaaaatgtgg
cagtttatggaccagtctgacctggagaccatgaggagcctgaaggatgccatggcccag
cacgaatcttcctgcgagtacaagaaggtggtgacacgggcactgcatatccctggctgc
aaggtggttccgttttgtggggtgtttctgaaggagctctgtgaggtgcttgatggagcc
tcgggccttatgaagctttgcccgaggtacaattcccaagaagaagctctagagtttgta
gctgattacagtggacaagataatttcttacaacgagtgggacagaatggcttaaagaat
tcagagaaggagtccactgtcaacagcatctttcagatcatcaggagctgcagtcgaagc
ctggagattgaggaggaggacagccccagtgaagggagcagctccaggaaaaattccttg
aaggataaagcccgatggcagtttataattggagatttattggattctgaaaatgacatc
tttgagcagcccaaagattgggaccctcatggatcagaagagccacagaaggcctttgac
catgggacagagctcatcccgtggtatgtgctgtccatccaagctgatgtgcaccagttc
ctgctacagggggccacagtcatccactatgaccaagacacacacctctctgcccgctgc
ttccttcagcttcagcctgacaacagcaccttgacctggataaagcccactactgcttcc
ctagccagtgctaaagcaaaacttggtgtgcttagtaacacatctgagcctggaaaattc
ccattattgggcaatgctggattaagtggcctggtggagggggtcttggatctgttttca
gcaaaggctgtgtacatgggacaccctaacattgatatacacactgtgtgtgttcagaac
aaactgagtaacatgtctctctctgagactggtgtgacactgctctatggacttcagacc
acggacaataggttattgcactttgtggcaccaaagcacacagctaaaatgctctttagc
ggattgttggaactcactagagccgtgagaaagatgaggaagttccctgaccaaagacag
cagtggcttcggaaacagtacgtcagcctctaccaggaggatggacgatatgaaggccca
actttggctcatgctgtggagttgtttggtggcagacgatggagtactcgaaaccccagc
cccgggacatcagcaaagagtgcagaaaagcccaacatgcagagaaacaacaccttgggt
ataagcaccaccaagaaaaagaagaaaatccttatgaggggggagagtggagaggcaacc
gacgatgagatggccatgcgaaaggccaaaacgcacaaagagtgtcggagccggagtggt
tctgatcctcaagacattaatgaacaagaggaatcagaggcgaataccatcacgagccct
cctaaccctctcccttccagaagagctcactctttgaccacggctgggtcccctaacgtg
gctgccgggacatcatctcccatcaggccagtgtcctcccctgtgctgtcttcttcaaac
aagagcccgtccagtgcctggagcagcagcagctggcatgggcggatcaaaggaggaatg
aagggctttcagagcttcatggtttcagacagcaacatgagttttgtggaatttgtcgag
ctgttcaaatcattcagtgtgaggagccgcaaggacctgaaggatctctttgacatctac
gccgtgccctgcgaccgagctggctctgagccggcccccctctacaccaacctgaccatt
gatgaaaacaccagcggtcttcagcctgatctagatttgttgaccagaaatgtctcggat
ttgggattattcattaagagtaaacagcagctgtctgacaaccagaggcaaatatctgat
gccattgctgctgcaagtatcgtgacaaacggcactggggtggagagcacatccctgggc
gtatttgggattggcatcctccagctcaatgacttcctagtgaattgccaaggagaacac
tgcacttatgatgaaattctcagcatcatccagaagtttgagcctagcgttagtatgtgt
catcagggactgatgtcatttgaaggatttgcaagatttctgatggataaagataatttt
gcctcgaaaaatgatgaatcgcaggagaacatcaaagaattgcagctgcccctctcctat
tattacattgaatcttcacacaatacctacctcacgggccatcagctcaaaggagaatcc
tcagtagaactctacagtcaggtcctgctgcaaggctgtaggagtgtagagttggactgc
tgggacggagatgatgggatgcccatcatttatcatggacatacactgacaaccaagatc
cccttcaaggaagtggttgaagccatcgatcgcagtgccttcatcacttctgatctgcct
atcatcatatcaattgagaaccactgttcattgcctcagcaacgaaaaatggcagaaatt
ttcaagactgtgtttggagaaaaactggtggctaaattcttatttgagagtgatttctca
gatgatccaatgcttccctcacctgaccaactcagaagaaaagtgcttcttaaaaataag
aagttaaaagcccatcagacaccagtggatatcttaaagcaaaaggctcatcagctagca
tccatgcaagctcaggcttataatggtggcagtgccaaccccccacctgctaataacgaa
gaagaggaagatgaagaggatgaatatgattatgactatgaatccctctctgacgctgat
gtccttactgcttctcctgctcctaacagtcaggaagacaacattctagaagacagacct
gaaaataaatcatgtaatgacaagcttcagtttgagtataatgaagaaatccccaagagg
ataaagaaagcagataattctgcttgcaacaaaggaaaggtttatgacatggaactggga
gaagaattttatcttcctcagaataaaaaagaaagcagacagatcgcaccagagctttct
gaccttgtcatctattgccaagcagtaaaatttccaggcctgtcaactctaaatgcatct
ggctctagcagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaatccgggc
agaatgagccccggggagacagcatcatttaacaaaacatctggaaaaagttcctgtgaa
ggaatgcggcaggcctgggaggactcttcttcctccgtcaacccaaccacgtccctcagc
gccatcatcagaactcccaaatgctatcatatctcctcgctcaacgaaaacgctgccaaa
cgtctgtgtcgcaggtattctcagaagctgatccagcacactgcctgccagctgctgagg
acctacccggctgccacccgcatcgactcatcgaaccccaaccccctcatgttctggctt
catgggatacagctcgtggcactcaactaccagaccgatgacctccctttacacttaaat
gctgccatgtttgaggccaacggtggctgtggttatgttctgaaacccccagttctgtgg
gacaaaaactgccccatgtatcagaagttctctcccttggaaagagacctggacagcatg
gagcccgccatctattctttaactattgtttctgggcagaatgtgtgcccgagtaacagc
acaggaagcccctgtatcgaggttgacgtcctgggcatggccctggatagctgccacttc
cgcacgaagcccatccatcgcaatactctgaaccccatgtggaacgaacagttcctcttc
cgggttcactttgaagatctcctgtttcttcgttttgccgtcgtggagaacaacagctca
gcagtcactgctcagagaatcataccactcaaggctctaaagcgaggatatcgacatctt
cagctgcgaaacctccacaatgaagtcttggaaatctctagtttattcataaacagcagg
aggatggaagagaattcctctggcagtcctatgccagcctctttgatgtttaatacagaa
gaaagaaaatgtttgcagacccatagagtcacagtacatggggtccctggaccagagccc
tttactgttttctctataaatggaggcaccaaggcaaagcagctcctccaacaaattctg
accattgatcaagacactaaacctattgccacagactattttttgatggaagaaaaatat
tttatatctaaagaaaagaatgaatgtaggaaacaaccattccaaagagccattggtcca
gaagaggagatcatgcagattttaagcagctggtttccagaagagggatatgttggcagg
attgtcttaaaaacccagcaagaaaacctggaagagaaaagcattgttcaagatgacaag
gagatgatcttgagctcagaggaggagagtttctttgtccaagtgcatgacgtttctcca
gagcaaccgcggacggtcatcaaagcgccccgtgtcagcaccgcccaggatgtcatccag
cagacgttatgcaaagccaaatattcctatagcatcctcagcaaccccaacccaagtgac
tatgtgcttttggaagaggtggtgaaagacaccaccaacaagaagtcttctaccccaaag
tcctcccagcgcgtccttttggatcaggagtgtgtgtttcaagcccaaagcaagtggaaa
ggtgcaggaaaattcatccttaagctaaaggaacaggtgcaggcatcccgagaagacaaa
agaaaaggcatctcttttgcaagtgaactcaagaagctcaccaagtcaactaaacagccc
cgaggactcacatcacctgctccggtcttggcctcagaaagcgtccagaacaaggaggag
aaacctgcgggtggcttgtcctccagtgacacagtagactatcggcagtga
DBGET
integrated database retrieval system
