Sus scrofa (pig): 396755 Help Entry 396755            CDS       T01009                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism ssc  Sus scrofa (pig) Pathway ssc04010   MAPK signaling pathway ssc04014   Ras signaling pathway ssc04015   Rap1 signaling pathway ssc04022   cGMP-PKG signaling pathway ssc04066   HIF-1 signaling pathway ssc04068   FoxO signaling pathway ssc04072   Phospholipase D signaling pathway ssc04150   mTOR signaling pathway ssc04151   PI3K-Akt signaling pathway ssc04152   AMPK signaling pathway ssc04211   Longevity regulating pathway ssc04213   Longevity regulating pathway - multiple species ssc04520   Adherens junction ssc04910   Insulin signaling pathway ssc04913   Ovarian steroidogenesis ssc04923   Regulation of lipolysis in adipocytes ssc04930   Type II diabetes mellitus ssc04931   Insulin resistance ssc04932   Non-alcoholic fatty liver disease ssc04960   Aldosterone-regulated sodium reabsorption ssc05010   Alzheimer disease ssc05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:ssc00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     396755 (INSR)    04014 Ras signaling pathway     396755 (INSR)    04015 Rap1 signaling pathway     396755 (INSR)    04066 HIF-1 signaling pathway     396755 (INSR)    04068 FoxO signaling pathway     396755 (INSR)    04072 Phospholipase D signaling pathway     396755 (INSR)    04022 cGMP-PKG signaling pathway     396755 (INSR)    04151 PI3K-Akt signaling pathway     396755 (INSR)    04152 AMPK signaling pathway     396755 (INSR)    04150 mTOR signaling pathway     396755 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     396755 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     396755 (INSR)    04923 Regulation of lipolysis in adipocytes     396755 (INSR)    04913 Ovarian steroidogenesis     396755 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     396755 (INSR)   09149 Aging    04211 Longevity regulating pathway     396755 (INSR)    04213 Longevity regulating pathway - multiple species     396755 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     396755 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     396755 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     396755 (INSR)    04932 Non-alcoholic fatty liver disease     396755 (INSR)    04931 Insulin resistance     396755 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ssc01001]     396755 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:ssc04090]     396755 (INSR) Enzymes [BR:ssc01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      396755 (INSR) Protein kinases [BR:ssc01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    396755 (INSR) CD molecules [BR:ssc04090]  Proteins   396755 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like B2 DUF4476 Motif Other DBs NCBI-GeneID:  396755 NCBI-ProteinID:  XP_020939599 Ensembl:  ENSSSCG00000013564 Vega:  OTTSUSG00000003509 LinkDB All DBs Position 2:71797209..71939923 Genome browser AA seq 1382 aa AA seqDB search MGAGGRRGAAALPLLVAVAALLVSAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYNLMNITRGAVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC TIINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPTRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE RQAEDSELYELDYCLKGLKLPSRTWSPPFETEGSQKHNQSEYEESSGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFIPRKSSSGPAAEDARPSRKRRALGDVGNITAAVPTIPGF SNTSSTSTPTSSEEHRPFEKVVNRESLVISGLRHFTGYRIELQACNQDAPEERCSVAAYV SARTMPEAKADDIIGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCV SRRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIG PLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR EKITLLRELGQGSFGMVYEGNARDIVKGEPETRVAVKTVNESASLRERIEFLNEASVMKG FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV RWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDN CPERVTDLMRMCWQFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEME FEDMESVPLDRSSHSQREEAGGRDGGSALGLKRNYEEHISYTHMNGGKKNGRILTLPRSN PS NT seq 4149 nt NT seq  +upstreamnt  +downstreamnt atgggcgctgggggcaggcggggggcggcggccctgccgctgctggtggccgttgccgcg ctgctggtgagcgccgcgggccacctgtaccctggagaggtgtgcccagggatggatatc cggaataaccttacacggctgcacgagttggccaactgctcggtcatcgaaggacatttg cagatcctgttgatgttcaaaacgcggcccgaggatttccgagacctcagtttccccaaa ctcatcatgatcactgattacttgctgctcttccgggtctacgggctggagagcctgaag gacctgttccccaacctcaccgtcatccggggctcacgcctcttctttaactatgcgctg gtcatctttgagatggttcacttgaaggagcttggcctctacaatttgatgaacatcacc aggggtgctgtccgcatcgagaagaacaatgagctctgctacctggcgaccattgactgg tcgcgcatcctggactctgtggaggataattacattgtgctgaacaaagacgacaacgag gagtgtggggacatttgcccaggcactgcgaagggcaagaccaattgccctgccaccgtc atcaatgggcaatttgtcgagcggtgttggacgcacagtcactgccagaaagtgtgcccg accatctgtaagtcgcacggctgcactgctgagggcctctgctgtcacagcgagtgtttg ggcaactgctctgagccagacgaccccaccaagtgcgtggcctgccgcaacttctacctg gacggcagatgcgtggagacctgcccgcccccctactaccacttccaagactggcgctgc gtgaacttcagcttctgccaggacctgcacaacaaatgcaagaactcaaggaggcagggc tgccaccagtacgtcattcacaacaacaagtgtatccctgagtgcccctcagggtacacg atgaattccagcaacttgatgtgcactccgtgcctaggcccctgtcccaaagtgtgtcac ctcctggaaggcgagaagaccatcgactcagtgacatccgcccaggagctccgaggctgc accattatcaacgggagcctaatcatcaacattcgaggaggcaacaacctggcagccgaa ctagaggccaaccttggactcattgaggagatttcagggtacctgaaaatccgccgatcc tatgccctcgtgtcactttccttcttccggaagttgcgtctgatccgaggggagacgttg gaaattgggaactattctttctatgccttggacaaccagaacctaaggcaactgtgggac tggagcaaacacaacctcaccatcactcaggggaaactcttcttccattataatcccaaa ctctgcttgtcggaaattcacaagatggaggaagtttctggaaccaaggggcgccaggag agaaatgatattgccctgaagaccaatggggaccaggcgtcctgtgaaaatgagttactt aaattttcttacattcggacatcttatgacaagatcttgctgaagtgggagccgtattgg ccccccgacttccgagacctcctggggttcatgctcttctacaaagaggccccttatcag aacgtgacggagtttgacgggcaggatgcgtgtggctccaacagctggacggtggtggac attgacccgcctacgaggtccaatgaccccaagtcccagaaccatcctgggtggctgatg cgtggtctcaagccctggacccagtatgccatctttgtcaagactttggtcaccttttct gatgaacgacgcacctatggagccaagagtgacatcatctacgtccagacagatgccaca aatccttccgtccccctggatcccatctcggtttctaattcctcgtcccagatcattctg aagtggaagcccccctctgaccccaacggcaacatcacacactacctggtgttctgggag aggcaggcggaggacagtgagctgtatgaactggattattgcctcaaagggttgaagctg ccctcccggacctggtccccaccattcgagactgaggggtcccagaagcacaatcagagt gagtacgaggaatcctctggggaatgctgctcctgcccaaagaccgactcacagatcctc aaggagctggaggaatcatcattcaggaaaacgtttgaagattacctacacaatgtggta ttcatccccagaaaatcctcttcaggccctgctgccgaggacgctaggccatccaggaaa cgcagggcccttggtgacgtggggaacataacggcggccgtgcccaccattccgggtttc tccaacacctcctccaccagcactcccacgagctcagaggagcacagaccctttgagaag gtggtgaacagagagtcactggtcatctctggcctgcgtcacttcactggctatcgcatt gagctgcaggcttgcaaccaagatgcccccgaagagaggtgcagtgtggctgcgtatgtc agcgccaggaccatgcctgaagccaaggcagatgatatcattggccctgtgacccatgaa atcttcgagaacaacgtcgttcacttgatgtggcaggagccgaaggaacccaatggtctg attgtgctgtacgaagtgagttaccgacgatacggtgatgaggagctgcatctctgcgtc tcccgcaggcattttgctctggagcgaggctgcaggctacgcgggctgccacctgggaat tacagcgttcgagttcgggccacctccctggcgggtaatggctcctggacagaggccacc tatttctacgtgacagactatttagacgtcccatcaaatattgcaaaaattatcattggc cccctcatctttgtctttctcttcagtgttgtgattggaagcatttatctattcctgagg aagaggcagccggatgggccactgggaccattgtatgcttcttcgaaccccgagtacctc agtgccagcgatgtatttccatgttctgtgtacgtgccggacgagtgggaggtgcctcgg gagaagatcacgctcctgcgcgagctggggcagggctccttcggcatggtgtacgaggga aacgccagggacatcgtcaagggtgagccggagacccgtgtggcggtgaagacggtcaac gagtcggccagcctgcgagagcggatcgagtttctcaacgaggcctccgtcatgaagggc ttcacctgccaccatgtggtccgcctcctgggggtggtgtccaaaggccagccaacactg gtggtgatggagttgatggctcacggagacttaaagagttacctgcgttccctgcggccg gaggctgagaataaccccggccgccctccccctaccctgcaagagatgattcagatggca gcagagattgctgatgggatggcatacctgaacgccaagaagtttgtacaccgggacctc gccgcacgaaattgcatggtcgcccatgattttaccgtcaaaatcggagactttggaatg accagagacatctacgaaacggattactaccggaaagggggcaagggtctactgcccgtg cgatggatggcacccgaatccctgaaggacggggtctttaccacttcttccgacatgtgg tcctttggcgtcgtcctttgggaaattaccagcttggcagaacagccttaccaaggcctt tcaaacgagcaggtgttgaaatttgtcatggatggaggctatctggatcaacctgacaat tgtccagagagagtcaccgacctgatgcgcatgtgctggcagttcaaccccaagatgcgg ccgaccttcctggagattgttgacctgctcaaggacgacctgcaccccagctttcccgaa gtctccttcttccacagcgaggagaacaaagcacccgagagcgaggagctggagatggag tttgaggacatggagagcgtccccctggaccggtcctcacactcgcagagggaggaggcc gggggtcgggatggagggtccgcgctggggctaaagaggaactatgaggagcacatctcc tacacccacatgaacggaggcaagaaaaatggccggattctgactctgccccggtcaaat ccttcctaa

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