Streptomyces spectabilis: CP982_24075
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Entry
CP982_24075 CDS
T07323
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sspb
Streptomyces spectabilis
Pathway
sspb00860
Porphyrin metabolism
sspb01100
Metabolic pathways
sspb01110
Biosynthesis of secondary metabolites
sspb01120
Microbial metabolism in diverse environments
sspb01240
Biosynthesis of cofactors
Module
sspb_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sspb_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sspb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CP982_24075
Enzymes [BR:
sspb01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CP982_24075
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CP982_24075
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QEV61401
UniProt:
A0A516RBE4
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Position
5489888..5491558
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AA seq
556 aa
AA seq
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MSPTSNLPGLPAHGHVTFLGAGPGDPGLLTLRAVEALARADVLIAEPDVLDVVRVHARGG
VDTPLPQSADGTSESAQAPTAAPAQAAANLVMEAARGGRRVVRAVTGDPGLDTDAADEML
ACAAEGIPFEVVPGIATAVGVPAYAGVPLRDAQGTDVRFVDARTASDRCWSEVGASDGTV
VVSTALDSVAAAAGELVAAGRKPDTPMTVTIAGTTTRQRTWTATLGTIAQVLKQAKVLPS
PDGGRPVIAVVGERSAAARRDQLSWFESKPLFGWRVLVPRTKEQAASLSDQLRSYGAVPH
EVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIK
VAAVGEQTAAALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATET
LVAGLIDLGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKP
HNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAAALAEFGARRRAAAIEAGDPVTR
PSERRPGARRRRAAAP
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccacctcgaaccttcccggccttcccgcacacgggcacgtcacctttctcggt
gccggacccggagatccgggactgctgactctgcgcgccgtcgaggcgctggcccgagcg
gatgtgctgatcgccgagccggatgttctcgatgtcgtacgcgtgcatgcccgagggggt
gtggacacaccgctgccccagtcggctgacggcacgtcagagagcgctcaggcgccgact
gccgcaccggctcaggctgcggccaatcttgtcatggaggcggcgcggggcggcaggcgg
gtcgtgcgtgcggtgaccggtgaccccggtctggacacggacgccgcggacgagatgctc
gcctgtgccgccgagggcatccccttcgaggtggtgccgggcatcgcgaccgcggtgggc
gtgcccgcctacgcgggggtgccgctgcgcgacgcgcagggcacggacgtgcgcttcgtc
gacgcgcggaccgcgtccgaccgctgctggagcgaggtcggggcgtcggacgggaccgtg
gtggtctcgacggccctggactcggtggcggcggccgcgggcgaactggtcgccgccggg
cgcaagcccgacacgccgatgacggtgaccatcgccggtacgacgacgcgccagcgcacc
tggacggcgacgcttggcaccatcgcgcaggtcctcaagcaggcgaaggtcctcccctcg
cccgacgggggccggcccgtcatagccgtggtcggtgagcgttccgccgccgcccggcgc
gaccagttgtcgtggttcgagtcgaagccgctcttcgggtggcgggtgctcgtgccgcgc
acgaaggagcaggcggcgtcgctctccgaccagctgcgttcgtacggcgcggtgccgcac
gaggtgccgacgatcgccgtcgagccgccgcgcacgccccagcagatggagcgggcggtc
aaggggctcgtgaccgggcgctacgagtggatcgccttcacctcggtgaacgcggtcaag
gcggtgcgcgagaagttcgaggagtacgggctcgacgcccgtgccttcgcgggcatcaag
gtcgccgccgtgggcgagcagacggccgccgcgctcatcgccttcggcgtgaagccggac
ctggtgccgagcggggagcagtccgccgcgggcctcctggaggactggccgccgtacgac
cccgtcttcgacccgatcgaccgggtgttcctgccccgcgccgacatcgccacggagacc
ctcgtcgccgggctcatcgacctcgggtgggaggtcgacgacgtcaccgcctaccggacc
gtgcgggcctcgccgccgcccgcggagacccgcgaggcgatcaagggcggcggcttcgac
gccgtgctcttcacgtcgagcagcacggtgcggaacctggtcggcatcgccggcaagccg
cacaacgtgaccgtgatcgcctgcatcgggcccgccaccgcgaagaccgcggaggagcac
ggcctgcgcgtggacgtgatggctccggagccgtccgtgcacaagctggcggcggccctc
gcggagttcggcgcccggcgccgggccgccgcgatcgaggcgggcgatcccgtcacgcga
cccagtgagcgtcggccgggggcccggcggcgccgggcggccgcgccgtag
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